Professor | 张竹青 | 数字化转型顾问

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Name	张竹青
Contact Information	zhuqingzhang@ucas.ac.cn
Language ability	中文, 英语
Province	北京

Upload Avatar (500 x 500)

Name

张竹青

Contact Information

zhuqingzhang@ucas.ac.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Work Experience	2005-2007 - 北京大学，化学与分子工程学院，理论生物中心 - 博士后 2008-2011 - 多伦多大学，医学院生物化学系 - 博士后 2011.6-现在 - 中国科学院大学，生命科学学院 - 副教授、教授

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Work Experience

2005-2007 - 北京大学，化学与分子工程学院，理论生物中心 - 博士后
2008-2011 - 多伦多大学，医学院生物化学系 - 博士后
2011.6-现在 - 中国科学院大学，生命科学学院 - 副教授、教授

Areas of Focus	生物大分子构象变化相关的模拟及计算工作蛋白质折叠和别构机制固有无序蛋白质的结构特征和功能关系蛋白质体系相分离的机制
Publications	Evaluation of sequences-based predictors for phase separating protein, Shaofeng Liao, Yujun Zhang, Yifei Qi, Zhuqing Zhang, 2023 Prediction of liquid-liquid phase separating proteins using machine learning, Xiaoquan Chu†, Tanlin Sun†, Qian Li, Youjun Xu, Zhuqing Zhang, Luhua Lai, Jianfeng Pei, 2022 LLPSDB v2.0: an updated database of proteins undergoing liquid-liquid phase separation in vitro, Xi Wang†, Xiang Zhou†, Qinglin Yan†, Shaofeng Liao, Wenqin Tang, Peiyu Xu, Yangzhenyu Gao, Qian Li, Zhihui Dou, Weishan Yang, Beifang Huang, Jinhong Li, Zhuqing Zhang, 2022 LLPSDB: a database of proteins undergoing liquid–liquid phase separation in vitro, Qian Li†, Xiaojun Peng†, Yuanqing Li, Wenqin Tang, Jia'an Zhu, Jing Huang, Yifei Qi and Zhuqing Zhang, 2020 How calcium ion binding induces the conformational transition of the calmodulin N-terminal domain-an atomic level characterization, Likun Zhao, Luhua Lai, Zhuqing Zhang, 2019 Characterization of the structural ensembles of p53 TAD2 by molecular dynamics simulations with different force fields, Yanhua Ouyang, Likun Zhao, Zhuqing Zhang, 2018 A critical comparison of coarse-grained structure-based approaches and atomic models of protein folding, Jie Hu, Tao Chen, Moye Wang, Hue Sun Chan, Zhuqing Zhang, 2017 Influences of heterogeneous native contact energy and many-body interactions on the prediction of protein folding mechanisms, Zhuqing Zhang, Yanhua Ouyang, Tao Chen, 2016 Transition paths, diffusive processes, and preequilibria of protein folding, Zhuqing Zhang, and Hue Sun Chan, 2012 Native Topology, Local-Nonlocal Coupling, and Nonnative Interactions: Principles of Protein Folding from Coarse-Grained Models, Hue Sun Chan, Zhuqing Zhang, Stefan Wallin and Zhirong Liu, 2011 Competition between Native Topology and Nonnative Interactions in Simple and Complex Folding Kinetics of Natural and Designed Proteins, Zhuqing Zhang, and Hue Sun Chan, 2010 Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential, Zhuqing Zhang, Hao Chen, Luhua Lai, 2007 Molecular dynamics simulations on the oligomer formation process of the GNNQQNY peptide from yeast prion protein Sup35, Zhuqing Zhang, Hao Chen, Hongjun Bai, Luhua Lai, 2007

Areas of Focus

生物大分子构象变化相关的模拟及计算工作
蛋白质折叠和别构机制
固有无序蛋白质的结构特征和功能关系
蛋白质体系相分离的机制

Publications

Evaluation of sequences-based predictors for phase separating protein, Shaofeng Liao, Yujun Zhang, Yifei Qi*, Zhuqing Zhang*, 2023
Prediction of liquid-liquid phase separating proteins using machine learning, Xiaoquan Chu†, Tanlin Sun†, Qian Li, Youjun Xu, Zhuqing Zhang*, Luhua Lai*, Jianfeng Pei*, 2022
LLPSDB v2.0: an updated database of proteins undergoing liquid-liquid phase separation in vitro, Xi Wang†, Xiang Zhou†, Qinglin Yan†, Shaofeng Liao, Wenqin Tang, Peiyu Xu, Yangzhenyu Gao, Qian Li, Zhihui Dou, Weishan Yang, Beifang Huang, Jinhong Li, Zhuqing Zhang*, 2022
LLPSDB: a database of proteins undergoing liquid–liquid phase separation in vitro, Qian Li†, Xiaojun Peng†, Yuanqing Li, Wenqin Tang, Jia'an Zhu, Jing Huang, Yifei Qi and Zhuqing Zhang*, 2020
How calcium ion binding induces the conformational transition of the calmodulin N-terminal domain-an atomic level characterization, Likun Zhao, Luhua Lai*, Zhuqing Zhang*, 2019
Characterization of the structural ensembles of p53 TAD2 by molecular dynamics simulations with different force fields, Yanhua Ouyang, Likun Zhao, Zhuqing Zhang*, 2018
A critical comparison of coarse-grained structure-based approaches and atomic models of protein folding, Jie Hu, Tao Chen, Moye Wang, Hue Sun Chan*, Zhuqing Zhang*, 2017
Influences of heterogeneous native contact energy and many-body interactions on the prediction of protein folding mechanisms, Zhuqing Zhang*, Yanhua Ouyang, Tao Chen, 2016
Transition paths, diffusive processes, and preequilibria of protein folding, Zhuqing Zhang, and Hue Sun Chan*, 2012
Native Topology, Local-Nonlocal Coupling, and Nonnative Interactions: Principles of Protein Folding from Coarse-Grained Models, Hue Sun Chan*, Zhuqing Zhang, Stefan Wallin and Zhirong Liu, 2011
Competition between Native Topology and Nonnative Interactions in Simple and Complex Folding Kinetics of Natural and Designed Proteins, Zhuqing Zhang, and Hue Sun Chan*, 2010
Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential, Zhuqing Zhang, Hao Chen, Luhua Lai*, 2007
Molecular dynamics simulations on the oligomer formation process of the GNNQQNY peptide from yeast prion protein Sup35, Zhuqing Zhang, Hao Chen, Hongjun Bai, Luhua Lai*, 2007

模拟计算构象变化生物大分子蛋白质折叠别构机制固有无序蛋白质结构特征功能关系相分离

张竹青 - 中国科学院大学

谢伟 - 中山大学

龚海鹏 - 清华大学

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