Professor | 张蕾 | 数字化转型顾问

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Name	张蕾
Contact Information	zhangl@fjirsm.ac.cn
Language ability	中文, 英语
Province	福建

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Name

张蕾

Contact Information

zhangl@fjirsm.ac.cn

Language ability

中文, 英语

Province

福建

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2000-09至2007-01：华中农业大学博士 1996-09至2000-06：华中农业大学学士 2010：获得武汉大学优秀博士后奖
Work Experience	2023-06至今：中国科学院福建物质结构研究所博士导师 2019-12至今：中国科学院福建物质结构研究所研究员 2019-07至今：中国科学院大学硕士导师 2017-09至2018-09：美国圣约翰大学访问学者 2014-12至2019-12：中国科学院福建物质结构研究所副研究员 2012-02至2014-12：中国科学院福建物质结构研究所助理研究员 2010-09至2011-10：厦门大学科研助理 2007-08至2010-09：武汉大学博士后/讲师
Awards	第十五届福建省自然科学优秀学术论文一等奖 (2022)

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2000-09至2007-01：华中农业大学博士
1996-09至2000-06：华中农业大学学士
2010：获得武汉大学优秀博士后奖

Work Experience

2023-06至今：中国科学院福建物质结构研究所博士导师
2019-12至今：中国科学院福建物质结构研究所研究员
2019-07至今：中国科学院大学硕士导师
2017-09至2018-09：美国圣约翰大学访问学者
2014-12至2019-12：中国科学院福建物质结构研究所副研究员
2012-02至2014-12：中国科学院福建物质结构研究所助理研究员
2010-09至2011-10：厦门大学科研助理
2007-08至2010-09：武汉大学博士后/讲师

Awards

第十五届福建省自然科学优秀学术论文一等奖 (2022)

Areas of Focus	生物化学与分子生物学生物医用材料微生物学药学
Publications	The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts, 通讯作者, 2024 A Serum-Stable supramolecular drug carrier for chemotherapeutics fabricated by a Peptide-Photosensitizer conjugate, 第10作者, 2023 A multi-functional nano-system combining PI3K-110α/β inhibitor overcomes P-glycoprotein mediated MDR and improves anti-cancer efficiency, 通讯作者, 2023 CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells, 通讯作者, 2022 Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers, 第1作者, 2022 Ribociclib Inhibits P-gp-Mediated Multidrug Resistance in Human Epidermoid Carcinoma Cells, 第1作者, 2022 Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086, 通讯作者, 2021 Mechanisms of thrombosis and research progress on targeted antithrombotic drugs, 第1作者, 2021 Recent progress in antitumor functions of the intracellular antibodies, 通讯作者, 2020 A strategy for enhanced tumor targeting of photodynamic therapy based on Escherichia coli-driven drug delivery system, 未提及, 2020 Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells, 通讯作者, 2020 The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer, 第1作者, 2020 Research Progress of Structure Based Antitumor Drug Design, 第1作者, 2020 Naftifine enhances photodynamic therapy against Staphylococcus aureus by inhibiting staphyloxanthin expression, 第6作者, 2020 Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression, 第8作者, 2019 Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination, 未提及, 2018

Areas of Focus

生物化学与分子生物学
生物医用材料
微生物学
药学

Publications

The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts, 通讯作者, 2024
A Serum-Stable supramolecular drug carrier for chemotherapeutics fabricated by a Peptide-Photosensitizer conjugate, 第10作者, 2023
A multi-functional nano-system combining PI3K-110α/β inhibitor overcomes P-glycoprotein mediated MDR and improves anti-cancer efficiency, 通讯作者, 2023
CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells, 通讯作者, 2022
Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers, 第1作者, 2022
Ribociclib Inhibits P-gp-Mediated Multidrug Resistance in Human Epidermoid Carcinoma Cells, 第1作者, 2022
Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086, 通讯作者, 2021
Mechanisms of thrombosis and research progress on targeted antithrombotic drugs, 第1作者, 2021
Recent progress in antitumor functions of the intracellular antibodies, 通讯作者, 2020
A strategy for enhanced tumor targeting of photodynamic therapy based on Escherichia coli-driven drug delivery system, 未提及, 2020
Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells, 通讯作者, 2020
The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer, 第1作者, 2020
Research Progress of Structure Based Antitumor Drug Design, 第1作者, 2020
Naftifine enhances photodynamic therapy against Staphylococcus aureus by inhibiting staphyloxanthin expression, 第6作者, 2020
Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression, 第8作者, 2019
Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination, 未提及, 2018

生物化学分子生物学生物医用材料微生物学药学肿瘤机制抗肿瘤药物口服疫苗蛋白质功能基因调控

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