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张蕾
Life Science
中国科学院大学
福建
Language: 中文, 英语
生物化学
分子生物学
生物医用材料
微生物学
药学
肿瘤机制
抗肿瘤药物
口服疫苗
蛋白质功能
基因调控
Areas of Focus
- 生物化学与分子生物学
- 生物医用材料
- 微生物学
- 药学
Work Experience
- 2023-06至今：中国科学院福建物质结构研究所博士导师
- 2019-12至今：中国科学院福建物质结构研究所研究员
- 2019-07至今：中国科学院大学硕士导师
- 2017-09至2018-09：美国圣约翰大学访问学者
- 2014-12至2019-12：中国科学院福建物质结构研究所副研究员
- 2012-02至2014-12：中国科学院福建物质结构研究所助理研究员
- 2010-09至2011-10：厦门大学科研助理
- 2007-08至2010-09：武汉大学博士后/讲师
Academic Background & Achievements
- 2000-09至2007-01：华中农业大学博士
- 1996-09至2000-06：华中农业大学学士
- 2010：获得武汉大学优秀博士后奖
Publications
- The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts, 通讯作者, 2024
- A Serum-Stable supramolecular drug carrier for chemotherapeutics fabricated by a Peptide-Photosensitizer conjugate, 第10作者, 2023
- A multi-functional nano-system combining PI3K-110α/β inhibitor overcomes P-glycoprotein mediated MDR and improves anti-cancer efficiency, 通讯作者, 2023
- CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells, 通讯作者, 2022
- Progress in the studies on the molecular mechanisms associated with multidrug resistance in cancers, 第1作者, 2022
- Ribociclib Inhibits P-gp-Mediated Multidrug Resistance in Human Epidermoid Carcinoma Cells, 第1作者, 2022
- Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086, 通讯作者, 2021
- Mechanisms of thrombosis and research progress on targeted antithrombotic drugs, 第1作者, 2021
- Recent progress in antitumor functions of the intracellular antibodies, 通讯作者, 2020
- A strategy for enhanced tumor targeting of photodynamic therapy based on Escherichia coli-driven drug delivery system, 未提及, 2020
- Plasminogen activator inhibitor (PAI) trap3, an exocellular peptide inhibitor of PAI-1, attenuates the rearrangement of F-actin and migration of cancer cells, 通讯作者, 2020
- The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer, 第1作者, 2020
- Research Progress of Structure Based Antitumor Drug Design, 第1作者, 2020
- Naftifine enhances photodynamic therapy against Staphylococcus aureus by inhibiting staphyloxanthin expression, 第6作者, 2020
- Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression, 第8作者, 2019
- Properties and applications of nanoparticle/microparticle conveyors with adjuvant characteristics suitable for oral vaccination, 未提及, 2018
Awards
- 第十五届福建省自然科学优秀学术论文一等奖 (2022)
