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竺淑佳
Life Science
中国科学院大学
上海
Language: 英语, 中文, 法语
突触蛋白
结构
功能
自身免疫性脑炎
分子机制
病理生理学
神经药理学
结构生物学
计算生物学
配体门控离子通道
Areas of Focus
- 突触蛋白的结构与功能
- 自身免疫性脑炎的分子机制及病理生理学研究
- 基于结构与计算生物学的神经药理学
Academic Background & Achievements
- 2009-09--2013-09 博士: 法国巴黎第六大学
- 2006-09--2009-06 硕士: 华东师范大学
- 2002-09--2006-06 本科: 浙江工业大学
Publications
- Structural basis of ketamine action on human NMDA receptors, Zhang Y*, Ye F*, Zhang T*, Lv S, Zhou L, Du D, Lin H, Guo F, Luo C#, Zhu S#, 2021
- Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors, Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, Zhang X, Paoletti P, Zhu S#, 2021
- Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits, Zhang J*, Zhang M*, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S#, 2023
- Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors, Zhang J*, Chang S*, Xu P*, Miao M, Wu H, Zhang Y, Zhang T, Wang H, Zhang J, Xie C, Song N, Luo C#, Zhang X#, Zhu S#, 2018
- Mechanism of NMDA receptor inhibition and activation, Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E, 2016
- Genetically encoding a light-switch in an ionotropic glutamate receptor reveals subunit-specific interfaces, Zhu S*, Riou M*, Yao A, Carvalho S, Rodriguez P, Bensaude O, Paoletti P#, Ye S#, 2014
- Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain, Zhu S, Stroebel D, C.Andrea Y, Taly A, Paoletti P, 2013
- Cryo-EM structure of human heptameric Pannexin 1 channel, Qu R*, Dong L*, Zhang J, Yu X#, Wang L#, Zhu S#, 2020
- Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors, Zeng Y, Zheng Y, Zhang T, Ye F, Zhan L, Kou Z, Zhu S#, Gao Z#, 2022
- NMDA receptors as therapeutic targets for depression treatment: Evidence from clinical to basic research, Lv S, Yao K, Zhang Y, Zhu S#, 2023
- Mechanisms of PiT2-loop7 Missense Mutations Induced Pi Dyshomeostasis, Sun, H, Xu, X, Ma T, Cui J, Liu M, Xiong B. Zhu S#, Liu J#, 2022
- Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profiling, Zhou Y, Liu Z, Zhang J, Dou T, Chen J, Ge G, Zhu S#, Wang F#, 2019
- Structure and symmetry inform gating principles of ionotropic glutamate receptors, Zhu S, Gouaux E, 2017
- Controlling NMDA Receptor Subunit Composition Using Ectopic Retention Signals, Stroebel D, Carvalho S, Grand T, Zhu S, Paoletti P, 2014
- Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines, Mony L, Zhu S, Carvalho S, Paoletti P, 2011
- Allosteric modulators of NMDA receptors: multiple sites and mechanisms, Zhu S, Paoletti P, 2015
