Professor | 赵博 | 数字化转型顾问

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Name	赵博
Contact Information	zhaobo@mail.kiz.ac.cn
Language ability	中文, 英语
Province	云南

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Name

赵博

Contact Information

zhaobo@mail.kiz.ac.cn

Language ability

中文, 英语

Province

云南

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2013-06 理学博士学位: 中国科学院大学 2003-09--2007-06 学士学位: 烟台大学
Work Experience	2020-09~现在 - 中国科学院昆明动物研究所 - 研究员 2017-06~2020-07 - Wistar研究所（美国费城） - 博士后 2016-01~2017-05 - 中国科学院昆明动物研究所 - 副研究员 2013-07~2015-12 - 中国科学院昆明动物研究所 - 助理研究员
Awards	国际干细胞学会年会旅行奖 (2016): 一等奖云南省科研机构联合会优秀论文奖 (2016): 一等奖国际干细胞学会年会旅行奖 (2015): 一等奖

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2013-06 理学博士学位: 中国科学院大学
2003-09--2007-06 学士学位: 烟台大学

Work Experience

2020-09~现在 - 中国科学院昆明动物研究所 - 研究员
2017-06~2020-07 - Wistar研究所（美国费城） - 博士后
2016-01~2017-05 - 中国科学院昆明动物研究所 - 副研究员
2013-07~2015-12 - 中国科学院昆明动物研究所 - 助理研究员

Awards

国际干细胞学会年会旅行奖 (2016): 一等奖
云南省科研机构联合会优秀论文奖 (2016): 一等奖
国际干细胞学会年会旅行奖 (2015): 一等奖

Areas of Focus	基因组稳定调控干细胞类器官技术环境污染毒理
Publications	Lnc956 -TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis, 第11作者, 2023 TXNRD1 drives innate immune response in senescent cells to promote tumor immune surveillance and age-associated inflammation, 第2作者, 2023 Purification of Long Non-coding RNAs on Replication Forks Using iROND (Isolate RNAs on Nascent DNA), 第11作者, 2023 EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1,TRF2,and RAD50, 第11作者, 2023 RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma, 第11作者, 2022 Sensitization of ovarian tumor to immune checkpoint blockade by boosting senescence-associated secretory phenotype, 第2作者, 2021 EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition, 第3作者, 2020 Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia, 第4作者, 2020 Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence, 第1作者, 2020 KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells, 第4作者, 2019 ARID1A promotes genomic stability through protecting telomere cohesion, 第1作者, 2019 In vitro culture of cynomolgus monkey embryos beyond early gastrulation, 第10作者, 2019 mouseembryonicstemcellshaveincreasedcapacityforreplicationforkrestartdrivenbythespecificfiliaflopedproteincomplex, 第1作者, 2018 BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer, 第4作者, 2017 Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability, 第1作者, 2015 Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal, 第2作者, 2013 In vitro generation of myofibroblasts-like cells from liver epithelial progenitor cells of rhesus monkey (Macaca mulatta), 第7作者, 2011

Areas of Focus

基因组稳定调控
干细胞类器官技术
环境污染毒理

Publications

Lnc956 -TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis, 第11作者, 2023
TXNRD1 drives innate immune response in senescent cells to promote tumor immune surveillance and age-associated inflammation, 第2作者, 2023
Purification of Long Non-coding RNAs on Replication Forks Using iROND (Isolate RNAs on Nascent DNA), 第11作者, 2023
EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1,TRF2,and RAD50, 第11作者, 2023
RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma, 第11作者, 2022
Sensitization of ovarian tumor to immune checkpoint blockade by boosting senescence-associated secretory phenotype, 第2作者, 2021
EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition, 第3作者, 2020
Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia, 第4作者, 2020
Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence, 第1作者, 2020
KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells, 第4作者, 2019
ARID1A promotes genomic stability through protecting telomere cohesion, 第1作者, 2019
In vitro culture of cynomolgus monkey embryos beyond early gastrulation, 第10作者, 2019
mouseembryonicstemcellshaveincreasedcapacityforreplicationforkrestartdrivenbythespecificfiliaflopedproteincomplex, 第1作者, 2018
BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer, 第4作者, 2017
Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability, 第1作者, 2015
Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal, 第2作者, 2013
In vitro generation of myofibroblasts-like cells from liver epithelial progenitor cells of rhesus monkey (Macaca mulatta), 第7作者, 2011

基因组稳定 Dna复制干细胞类器官毒理学环境污染细胞生物学遗传学分子生物学癌症研究

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