Upload Avatar (500 x 500)
赵博
Life Science
中国科学院大学
云南
Language: 中文, 英语
基因组稳定
Dna复制
干细胞
类器官
毒理学
环境污染
细胞生物学
遗传学
分子生物学
癌症研究
Areas of Focus
- 基因组稳定调控
- 干细胞类器官技术
- 环境污染毒理
Work Experience
- 2020-09~现在 - 中国科学院昆明动物研究所 - 研究员
- 2017-06~2020-07 - Wistar研究所（美国费城） - 博士后
- 2016-01~2017-05 - 中国科学院昆明动物研究所 - 副研究员
- 2013-07~2015-12 - 中国科学院昆明动物研究所 - 助理研究员
Academic Background & Achievements
- 2007-09--2013-06 理学博士学位: 中国科学院大学
- 2003-09--2007-06 学士学位: 烟台大学
Publications
- Lnc956 -TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis, 第11作者, 2023
- TXNRD1 drives innate immune response in senescent cells to promote tumor immune surveillance and age-associated inflammation, 第2作者, 2023
- Purification of Long Non-coding RNAs on Replication Forks Using iROND (Isolate RNAs on Nascent DNA), 第11作者, 2023
- EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1,TRF2,and RAD50, 第11作者, 2023
- RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma, 第11作者, 2022
- Sensitization of ovarian tumor to immune checkpoint blockade by boosting senescence-associated secretory phenotype, 第2作者, 2021
- EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition, 第3作者, 2020
- Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia, 第4作者, 2020
- Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence, 第1作者, 2020
- KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells, 第4作者, 2019
- ARID1A promotes genomic stability through protecting telomere cohesion, 第1作者, 2019
- In vitro culture of cynomolgus monkey embryos beyond early gastrulation, 第10作者, 2019
- mouseembryonicstemcellshaveincreasedcapacityforreplicationforkrestartdrivenbythespecificfiliaflopedproteincomplex, 第1作者, 2018
- BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer, 第4作者, 2017
- Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability, 第1作者, 2015
- Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal, 第2作者, 2013
- In vitro generation of myofibroblasts-like cells from liver epithelial progenitor cells of rhesus monkey (Macaca mulatta), 第7作者, 2011
Awards
- 国际干细胞学会年会旅行奖 (2016): 一等奖
- 云南省科研机构联合会优秀论文奖 (2016): 一等奖
- 国际干细胞学会年会旅行奖 (2015): 一等奖
