Areas of Focus
- 胆固醇代谢性疾病药物药理学
- 非酒精性脂肪性肝炎药理学
Work Experience
- 2022-06 - 现在 - 中国科学院昆明植物研究所 - 研究员，研究组组长，引进杰出人才
- 2022-01 - 2022-06 - 武汉大学 生命科学学院 - 研究助理
- 2018-08 - 2022-05 - 上海科技大学 生命科学与技术学院 - 访问学者
- 2016-04 - 2018-07 - 中国科学院上海生物化学与细胞生物学研究所 - 访问学者
- 2016-02 - 2022-01 - 武汉大学 生命科学学院 - 博士后
Publications
- Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol, Xiao-Zheng Su, Lin-Fei Zhang, Kun Hu, Yang An, Qiao-Peng Zhang, Jian-Wei Tang, Bing-Chao Yan, Xing-Ren Li, Jie Cai, Xiao-Nian Li, Han-Dong Sun, Shi-You Jiang, Pema-Tenzin Puno, 2024
- Discovery of an insulin-induced gene binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting sterol regulatory element-binding protein-mediated lipogenesis, Shi-You Jiang, Xinglin Yang, Zimo Yang, JueWan Li, MengQiang Xu, YuXiu Qu, JingJie Tang, YunFeng Li, Liguo Wang, YiWen Shao, XinYuan Meng, Huili Hu, BaoLiang Song, Yu Rao, Wei Qi, 2022
- Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol, Shi-You Jiang, Hui Li, JingJie Tang, Jie Wang, Jie Luo, Bing Liu, JinKai Wang, XiongJie Shi, HaiWei Cui, Jie Tang, Fan Yang, Wei Qi, WenWei Qiu, BaoLiang Song, 2018
- Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase, Shi-You Jiang, JingJie Tang, Xiao Xu, Wei Qi, Suqian Wu, Chao Jiang, Jiaxu Hong, Jianjiang Xu, BaoLiang Song, Jie Luo, 2019
- Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol, XingZi Li, Shi-You Jiang, GuoQiang Li, QianRu Jiang, JueWan Li, ChenChen Li, YuQin Han, BaoLiang Song, XinRan Ma, Wei Qi, WenWei Qiu, 2022
- A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption, YingYu Zhang, ZhenYan Fu, Jian Wei, Wei Qi, Gulinaer Baituola, Jie Luo, YaJie Meng, ShuYuan Guo, Huiyong Yin, Shi-You Jiang, YunFeng Li, HongHua Miao, Yong Liu, Yan Wang, BoLiang Li, YiTong Ma, BaoLiang Song, 2018
- A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation, Shi-You Jiang, Jiacheng Du, Qinghua Kong, Chaocui Li, Yan Li, Handong Sun, Jianxin Pu, Bingyu Mao, 2015
- Interferon-Lambda3 (IFN-lambda 3) and Its Cognate Receptor Subunits in Tree Shrews (Tupaia belangeri): Genomic Sequence Retrieval, Molecular Identification and Expression Analysis, MingLi Li, WenWen Xu, YueDong Gao, Yan Guo, WenJu Wang, Chao Wang, Shi-You Jiang, Andrew Willden, JingFei Huang, HuaTang Zhang, 2013
- Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with beta-Catenin/TCF4 Interaction in Colorectal Cancer Cells, Xingyao Li, Jianxin Pu, Shi-You Jiang, Jia Su, Lingmei Kong, Bingyu Mao, Handong Sun, Yan Li, 2013
Awards
- 2022 - 中国门脉高压与肝硬化十大原创研究
- 2022 - 中国细胞生物学学会Discover Glo Explorer青年科学家奖
- 2022 - 上海科技大学第四届科研图像大赛一等奖
- 2022 - 上海科技大学第四届科研图像大赛二等奖
- 2022 - 上海科技大学第四届科研图像大赛三等奖
- 2017 - 中国科学院上海生物化学与细胞生物学研究所优秀显微镜图片
- 2016 - 中国科学院上海生物化学与细胞生物学研究所优秀显微镜图片
- 2013 - 中国细胞生物学学会显微摄影大赛三等奖
- 2013 - 奥林巴斯中国显微图像大赛
