Areas of Focus
- 肿瘤免疫治疗研究
- 人源化小鼠研究
Work Experience
- 2016-07~现在 - 中国科学院广州生物医药与健康研究院 - 副研究员
- 2012-07~2013-09 - 中国科学院广州生物医药与健康研究院 - 研究实习员
Academic Background & Achievements
- 2013-09--2016-06 博士学位: 中国科学院广州生物医药与健康研究院
- 2009-09--2012-07 医学硕士: 汕头大学
- 2005-09--2009-07 理学学士: 烟台大学
Publications
- CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation, 第8作者, 2019
- Linifanib exerts dual anti-obesity effect by regulating adipocyte browning and formation, 第5作者, 2019
- DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells, 第3作者, 2018
- InVitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity, 合作组作者, 2018
- Emerging role of C5a/C5aR IL-17A axis in cGVHD, 合作组作者, 2018
- Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia, 第3作者, 2018
- A novel generation 1928zT2 CAR T cells induce remission in extramedullary relapse of acute lymphoblastic leukemia, 第5作者, 2018
- The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells, 第7作者, 2017
- Low-dose decitabine enhances chidamide-induced apoptosis in adult acute lymphoblast leukemia, especially for p16-deleted patients through DNA damage, 第4作者, 2017
- Toll-like Receptor 2 Costimulation Potentiates the Antitumor Efficacy of CAR T Cells, 第7作者, 2017
- Anti-GPC3 CAR T cells suppress the growth of tumour cells in patient-derived xenografts of hepatocellular carcinoma, 第1作者, 2017
- Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia, 第1作者, 2017
- Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption, 第4作者, 2016
- GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways, 第2作者, 2016
- Identification of growth factors that promote the proliferation and drug resistance of human primary acute B lymphoblastic cells, 第2作者, 2016
- Influenza Virus Induces Inflammatory Response in Mouse Primary Cortical Neurons with Limited Viral Replication, 第3作者, 2016
- Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models, 第2作者, 2016
- Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2016
- CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia, 第1作者, 2016
- Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2015
- A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor, 第6作者, 2015
- Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments, 第2作者, 2015
- Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes, 第2作者, 2015
- ANGPTL7 regulates the expansion and repopulation of human
Awards
- 2019: 二等奖, 人源化小鼠及其临床前评估平台的建立及应用, 省级
- 2017: 中国专利优秀奖, 国家级
- 2017: 广东省专利优秀奖, 省级
