Professor | 蒋治武 | 数字化转型顾问

Name	蒋治武
Contact Information	jiang_zhiwu@gibh.ac.cn
Language ability	中文, 英文
Province	广东

Name

蒋治武

Contact Information

jiang_zhiwu@gibh.ac.cn

Language ability

中文, 英文

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2013-09--2016-06 博士学位: 中国科学院广州生物医药与健康研究院 2009-09--2012-07 医学硕士: 汕头大学 2005-09--2009-07 理学学士: 烟台大学
Work Experience	2016-07~现在 - 中国科学院广州生物医药与健康研究院 - 副研究员 2012-07~2013-09 - 中国科学院广州生物医药与健康研究院 - 研究实习员
Awards	2019: 二等奖, 人源化小鼠及其临床前评估平台的建立及应用, 省级 2017: 中国专利优秀奖, 国家级 2017: 广东省专利优秀奖, 省级

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2013-09--2016-06 博士学位: 中国科学院广州生物医药与健康研究院
2009-09--2012-07 医学硕士: 汕头大学
2005-09--2009-07 理学学士: 烟台大学

Work Experience

2016-07~现在 - 中国科学院广州生物医药与健康研究院 - 副研究员
2012-07~2013-09 - 中国科学院广州生物医药与健康研究院 - 研究实习员

Awards

2019: 二等奖, 人源化小鼠及其临床前评估平台的建立及应用, 省级
2017: 中国专利优秀奖, 国家级
2017: 广东省专利优秀奖, 省级

Areas of Focus	肿瘤免疫治疗研究人源化小鼠研究
Publications	CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation, 第8作者, 2019 Linifanib exerts dual anti-obesity effect by regulating adipocyte browning and formation, 第5作者, 2019 DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells, 第3作者, 2018 InVitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity, 合作组作者, 2018 Emerging role of C5a/C5aR IL-17A axis in cGVHD, 合作组作者, 2018 Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia, 第3作者, 2018 A novel generation 1928zT2 CAR T cells induce remission in extramedullary relapse of acute lymphoblastic leukemia, 第5作者, 2018 The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells, 第7作者, 2017 Low-dose decitabine enhances chidamide-induced apoptosis in adult acute lymphoblast leukemia, especially for p16-deleted patients through DNA damage, 第4作者, 2017 Toll-like Receptor 2 Costimulation Potentiates the Antitumor Efficacy of CAR T Cells, 第7作者, 2017 Anti-GPC3 CAR T cells suppress the growth of tumour cells in patient-derived xenografts of hepatocellular carcinoma, 第1作者, 2017 Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia, 第1作者, 2017 Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption, 第4作者, 2016 GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways, 第2作者, 2016 Identification of growth factors that promote the proliferation and drug resistance of human primary acute B lymphoblastic cells, 第2作者, 2016 Influenza Virus Induces Inflammatory Response in Mouse Primary Cortical Neurons with Limited Viral Replication, 第3作者, 2016 Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models, 第2作者, 2016 Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2016 CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia, 第1作者, 2016 Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2015 A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor, 第6作者, 2015 Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments, 第2作者, 2015 Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes, 第2作者, 2015 ANGPTL7 regulates the expansion and repopulation of human

Areas of Focus

肿瘤免疫治疗研究
人源化小鼠研究

Publications

CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation, 第8作者, 2019
Linifanib exerts dual anti-obesity effect by regulating adipocyte browning and formation, 第5作者, 2019
DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells, 第3作者, 2018
InVitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity, 合作组作者, 2018
Emerging role of C5a/C5aR IL-17A axis in cGVHD, 合作组作者, 2018
Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia, 第3作者, 2018
A novel generation 1928zT2 CAR T cells induce remission in extramedullary relapse of acute lymphoblastic leukemia, 第5作者, 2018
The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells, 第7作者, 2017
Low-dose decitabine enhances chidamide-induced apoptosis in adult acute lymphoblast leukemia, especially for p16-deleted patients through DNA damage, 第4作者, 2017
Toll-like Receptor 2 Costimulation Potentiates the Antitumor Efficacy of CAR T Cells, 第7作者, 2017
Anti-GPC3 CAR T cells suppress the growth of tumour cells in patient-derived xenografts of hepatocellular carcinoma, 第1作者, 2017
Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia, 第1作者, 2017
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption, 第4作者, 2016
GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways, 第2作者, 2016
Identification of growth factors that promote the proliferation and drug resistance of human primary acute B lymphoblastic cells, 第2作者, 2016
Influenza Virus Induces Inflammatory Response in Mouse Primary Cortical Neurons with Limited Viral Replication, 第3作者, 2016
Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models, 第2作者, 2016
Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2016
CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia, 第1作者, 2016
Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized, 第1作者, 2015
A New Strategy to Target Acute Myeloid Leukemia Stem and Progenitor Cells Using Chidamide, a Histone Deacetylase Inhibitor, 第6作者, 2015
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments, 第2作者, 2015
Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes, 第2作者, 2015
ANGPTL7 regulates the expansion and repopulation of human

Car T细胞恶性肿瘤免疫治疗临床前评估临床转化 Pdx模型人源化小鼠模型肝脏人源化肿瘤异种移植免疫缺陷

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