Professor | 刘雅兰 | 数字化转型顾问

Name	刘雅兰
Contact Information	liuyl@wh.iov.cn
Language ability	中文, 英语
Province	湖北

Name

刘雅兰

Contact Information

liuyl@wh.iov.cn

Language ability

中文, 英语

Province

湖北

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2005-09--2010-06 博士学位: 中国科学院武汉病毒研究所 1999-09--2003-06 理学学士: 湖北大学
Work Experience	2018-09~现在 - 中国科学院武汉病毒研究所 - 副研究员 2010-07~2018-08 - 中国科学院武汉病毒研究所 - 助理研究员 2005-09~2010-06 - 中国科学院武汉病毒研究所 - 博士学位 2003-08~2005-06 - 湖北省公安县第一高级中学 - 生物教师 1999-09~2003-06 - 湖北大学 - 理学学士

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2005-09--2010-06 博士学位: 中国科学院武汉病毒研究所
1999-09--2003-06 理学学士: 湖北大学

Work Experience

2018-09~现在 - 中国科学院武汉病毒研究所 - 副研究员
2010-07~2018-08 - 中国科学院武汉病毒研究所 - 助理研究员
2005-09~2010-06 - 中国科学院武汉病毒研究所 - 博士学位
2003-08~2005-06 - 湖北省公安县第一高级中学 - 生物教师
1999-09~2003-06 - 湖北大学 - 理学学士

Areas of Focus	病毒与宿主相互作用的分子机制 HSV-2/HIV-1的共感染及抑制自复制RNA疫苗 HIV-1抑制剂抗病毒药物研究
Publications	Tat-dependent conditionally replicating adenoviruses expressing diphtheria toxin A for specifically killing HIV-1-infected cells, 第11作者, 2024 Advances in saRNA Vaccine Research against Emerging/Re-Emerging Viruses, 第11作者, 2023 Migrasomes released by HSV-2-infected cells serve as a conveyance for virus spread, 第11作者, 2023 Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22), 第11作者, 2022 A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration, 第11作者, 2021 Herpes Simplex Virus Type 2 Glycoprotein D Inhibits NF-kB Activation by Interacting with p65, 第11作者, 2021 Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells, 第7作者, 2020 Self-assembled fluorescent Ce(III) coordination polymer as ratiometric probe for HIV antigen detection, 第9作者, 2019 Hsv-2 glycoprotein j promotes viral protein expression and virus spread, 第1作者, 2018 Tick-borne encephalitis virus nonstructural protein ns5 induces rantes expression dependent on the rna-dependent rna polymerase activity, 第11作者, 2018 Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4 + T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4, 第12作者, 2018 DC-SIGN promotes Japanese encephalitis virus transmission from dendritic cells to T cells via virological synapses, 第11作者, 2017 Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E, 第11作者, 2017 DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein, 第14作者, 2016 HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway, 第11作者, 2016 HSV-2 Immediate-Early Protein US1 Inhibits IFN-beta Production by Suppressing Association of IRF-3 with IFN-beta Promoter, 第2作者, 2015 Sensitivity of transmitted and founder human immunodeficiency virus type 1 envelopes to carbohydrate-binding agents griffithsin, cyanovirin-N and Galanthus nivalis agglutinin, 第5作者, 2015 Immunization with HSV-2 gB-CCL19 Fusion Constructs Protects Mice against Lethal Vaginal Challenge, 第10作者, 2015 Inhibition of HIV-1 infection of primary CD4(+) T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9, 第6作者, 2015 Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins, 第1作者, 2015 Contribution of N-linked glycans on HSV-2 gB to cell-cell fusion and viral entry, 第9作者, 2015 Binding of HIV-1 virions to α4β7 expressing cells and impact of antagonizing α4β7 on HIV-1 infection of primary CD4+ T cells, 第5作者, 2014 Human cytomegalovirus UL94 is a nucleocytoplasmic shuttling protein containing two NLSs and one NES, 第1作者

Areas of Focus

病毒与宿主相互作用的分子机制
HSV-2/HIV-1的共感染及抑制
自复制RNA疫苗
HIV-1抑制剂
抗病毒药物研究

Publications

Tat-dependent conditionally replicating adenoviruses expressing diphtheria toxin A for specifically killing HIV-1-infected cells, 第11作者, 2024
Advances in saRNA Vaccine Research against Emerging/Re-Emerging Viruses, 第11作者, 2023
Migrasomes released by HSV-2-infected cells serve as a conveyance for virus spread, 第11作者, 2023
Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22), 第11作者, 2022
A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration, 第11作者, 2021
Herpes Simplex Virus Type 2 Glycoprotein D Inhibits NF-kB Activation by Interacting with p65, 第11作者, 2021
Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells, 第7作者, 2020
Self-assembled fluorescent Ce(III) coordination polymer as ratiometric probe for HIV antigen detection, 第9作者, 2019
Hsv-2 glycoprotein j promotes viral protein expression and virus spread, 第1作者, 2018
Tick-borne encephalitis virus nonstructural protein ns5 induces rantes expression dependent on the rna-dependent rna polymerase activity, 第11作者, 2018
Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4 + T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4, 第12作者, 2018
DC-SIGN promotes Japanese encephalitis virus transmission from dendritic cells to T cells via virological synapses, 第11作者, 2017
Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E, 第11作者, 2017
DC-SIGN as an attachment factor mediates Japanese encephalitis virus infection of human dendritic cells via interaction with a single high-mannose residue of viral E glycoprotein, 第14作者, 2016
HSV-2 glycoprotein gD targets the CC domain of tetherin and promotes tetherin degradation via lysosomal pathway, 第11作者, 2016
HSV-2 Immediate-Early Protein US1 Inhibits IFN-beta Production by Suppressing Association of IRF-3 with IFN-beta Promoter, 第2作者, 2015
Sensitivity of transmitted and founder human immunodeficiency virus type 1 envelopes to carbohydrate-binding agents griffithsin, cyanovirin-N and Galanthus nivalis agglutinin, 第5作者, 2015
Immunization with HSV-2 gB-CCL19 Fusion Constructs Protects Mice against Lethal Vaginal Challenge, 第10作者, 2015
Inhibition of HIV-1 infection of primary CD4(+) T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9, 第6作者, 2015
Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins, 第1作者, 2015
Contribution of N-linked glycans on HSV-2 gB to cell-cell fusion and viral entry, 第9作者, 2015
Binding of HIV-1 virions to α4β7 expressing cells and impact of antagonizing α4β7 on HIV-1 infection of primary CD4+ T cells, 第5作者, 2014
Human cytomegalovirus UL94 is a nucleocytoplasmic shuttling protein containing two NLSs and one NES, 第1作者

病毒宿主相互作用分子机制 Hsv-2 Hiv-1 共感染抑制 Rna疫苗

胡勤学 - 中国科学院大学

张建超 - 南方科技大学

Area of Focus
肿瘤 | 发生 | 转移 | 分子 | 机制 | 癌症 | 生物学 | 细胞 | 生物化学 | 分子生物学

蓝柯 - 武汉大学

Area of Focus
疱疹病毒 | 癌症 | 病毒学 | 致病机理 | 新发 | 感染 | 病毒 | 机制 | 研究 | 分子

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