Professor | 王可品 | 数字化转型顾问

Name	王可品
Contact Information	wang_kepin@gibh.ac.cn
Language ability	中文, 英文
Province	广东

Name

王可品

Contact Information

wang_kepin@gibh.ac.cn

Language ability

中文, 英文

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2011-09到2016-07 理学博士: 中国科学院大学 2007-09到2011-07 工学学士: 安徽大学
Work Experience	2022-12到现在 - 中国科学院广州生物医药与健康研究院 - 研究员 2018-07到2022-12 - 中国科学院广州生物医药与健康研究院 - 副研究员 2018-01到2018-06 - 中国科学院广州生物医药与健康研究院 - 副研究员(试聘) 2016-07到2017-12 - 中国科学院广州生物医药与健康研究院 - 助理研究员
Awards	中国科学院广州分院2021-2022年度优秀青年科技工作者: 2023

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2011-09到2016-07 理学博士: 中国科学院大学
2007-09到2011-07 工学学士: 安徽大学

Work Experience

2022-12到现在 - 中国科学院广州生物医药与健康研究院 - 研究员
2018-07到2022-12 - 中国科学院广州生物医药与健康研究院 - 副研究员
2018-01到2018-06 - 中国科学院广州生物医药与健康研究院 - 副研究员(试聘)
2016-07到2017-12 - 中国科学院广州生物医药与健康研究院 - 助理研究员

Awards

中国科学院广州分院2021-2022年度优秀青年科技工作者: 2023

Areas of Focus	基因修饰大动物模型构建与应用新型基因编辑技术开发与优化
Publications	Enhancing prime editor flexibility with coiled-coil heterodimers, 王可品, 2024 Exonuclease editor promotes precision of gene editing in mammalian cells, 王可品, 2024 Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos, 王可品, 2023 Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription, 王可品, 2023 Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation, 王可品, 2023 Genome editing pig models with elements for controllable gene expression, 王可品, 2023 Genome-Wide CRISPR/Cas9 Screen Reveals a Role for SLC35A1 in the Adsorption of Porcine Deltacoronavirus, 王可品, 2022 AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns, 王可品, 2022 Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression, 王可品, 2022 CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I, 王可品, 2021 Improving Cpf1-mediated base editing system by combining dCas9/ dead sgRNA with human APOBEC3A variants, 王可品, 2021 Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses, 王可品, 2020 ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, 王可品, 2020 Efficient base editing for multiple genes and loci in pigs using base editors, 王可品, 2019 XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, 王可品, 2018 Engineering crispr/cpf1 with trna promotes genome editing capability in mammalian systems, 王可品, 2018 Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing, 王可品, 2017 Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering, 王可品, 2016

Areas of Focus

基因修饰大动物模型构建与应用
新型基因编辑技术开发与优化

Publications

Enhancing prime editor flexibility with coiled-coil heterodimers, 王可品, 2024
Exonuclease editor promotes precision of gene editing in mammalian cells, 王可品, 2024
Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos, 王可品, 2023
Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription, 王可品, 2023
Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation, 王可品, 2023
Genome editing pig models with elements for controllable gene expression, 王可品, 2023
Genome-Wide CRISPR/Cas9 Screen Reveals a Role for SLC35A1 in the Adsorption of Porcine Deltacoronavirus, 王可品, 2022
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns, 王可品, 2022
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression, 王可品, 2022
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I, 王可品, 2021
Improving Cpf1-mediated base editing system by combining dCas9/ dead sgRNA with human APOBEC3A variants, 王可品, 2021
Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses, 王可品, 2020
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, 王可品, 2020
Efficient base editing for multiple genes and loci in pigs using base editors, 王可品, 2019
XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, 王可品, 2018
Engineering crispr/cpf1 with trna promotes genome editing capability in mammalian systems, 王可品, 2018
Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing, 王可品, 2017
Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering, 王可品, 2016

基因修饰大动物模型基因编辑 Crispr 基因组生物技术分子生物学基因工程动物模型研究

田瑞琳 - 南方科技大学

张鹏 - 武汉大学

尹君 - 武汉大学

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们