徐进新
xu_jinxin@gibh.ac.cn
中文, 英文
广东
中国科学院大学
Medical School
  • 2006-09--2012-06 博士: 中国科学技术大学
  • 2002-09--2006-06 本科: 江西师范大学
  • 2024-04~现在 - 中国科学院广州生物医药与健康研究院 - 研究员
  • 2017-01~2024-04 - 中国科学院广州生物医药与健康研究院 - 副研究员
  • 2012-07~2016-12 - 中国科学院广州生物医药与健康研究院 - 助理研究员
表遗传调控因子在发育和癌症发生中的作用机制研究
囊泡运输及信号转导调控机制研究
  • Biochemical and Biophysical Research Communicationsnull, Not mentioned, 2023
  • Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins, Yulong Zhang, Rui Chen, Yan Dong, Jiabin Zhu, Kai Su, Jinsong Liu, Jinxin Xu, 2022
  • Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2, Jinxin Xu, Xin Jiang, Yulong Zhang, Yan Dong, Changli Ma, Hanqiu Jiang, Taisen Zuo, Rui Chen, Yubin Ke, He Cheng, Howard Wang, Jinsong Liu, 2022
  • Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist, Xishan Wu, Hui Shen, Yan Zhang, Chao Wang, Qiu Li, Cheng Zhang, Xiaoxi Zhuang, Chenchang Li, Yudan Shi, Yanli Xing, Qiuping Xiang, Jinxin Xu, Donghai Wu, Jinsong Liu, Yong Xu, 2021
  • Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition, Jinxin Xu, Xiaowen Tang, Yiguang Zhu, Zhijun Yu, Kai Su, Yulong Zhang, Yan Dong, Weiming Zhu, Changsheng Zhang, Ruibo Wu, Jinsong Liu, 2020
  • DDX24 Mutations Associated With Malformations of Major Vessels to the Viscera, Pengfei Pang, Xiaojun Hu, Bin Zhou, Junjie Mao, Yu Liang, Zaibo Jiang, Mingsheng Huang, Ruihong Liu, Youyong Zhang, Jiesheng Qian, Jinsong Liu, Jinxin Xu, Yaqin Zhang, Maoheng Zu, Yiming Wang, Huanhuan He, Hong Shan, 2019
  • Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer, Yan Zhang, Xishan Wu, Xiaoqian Xue, Chenchang Li, Junjian Wang, Rui Wang, Cheng Zhang, Chao Wang, Yudan Shi, Lingjiao Zou, Qiu Li, Zenghong Huang, Xiaojuan Hao, Kerry Loomes, Donghai Wu, HongWu Chen, Jinxin Xu, Yong Xu, 2019
  • Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding, Na Wang, Qingan Zou, Jinxin Xu, Jiancun Zhang, Jinsong Liu, 2018
  • SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding, Jinxin Xu, Leilei Zhang, Yinghua Ye, Yongli Shan, Chanjuan Wan, Junfeng Wang, Duanqing Pei, Xiaodong Shu, Jinsong Liu, 2017
  • Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain, Kai Su, Tingting Xu, Zhijun Yu, Jiabin Zhu, Yulong Zhang, Minhao Wu, Ying Xiong, Jinsong Liu, Jinxin Xu, 2017
  • Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A(2) group IIE, Shulin Hou, Tingting Xu, Jinxin Xu, Linbing Qu, Yong Xu, Ling Chen, Jinsong Liu, 2017
  • Structural insights into the binding mechanism of IDO1 with hydroxylamidine based inhibitor INCB14943, You Wu, Tingting Xu, Jinsong Liu, Ke Ding, Jinxin Xu, 2017
  • Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis, Yiguang Zhu, Jinxin Xu, Xiangui Mei, Zhan Feng, Liping Zhang, Qingbo Zhang, Guangtao Zhang, Weiming Zhu, Jinsong Liu, Changsheng Zhang, 2016
  • Structure of product-bound SMG1 lipase: active site gating implications, Shaohua Guo, Jinxin Xu, Ioannis V Pavlidis, Dongming Lan, Uwe T Bornscheuer, Jinsong Liu, Yonghua Wang, 2015
  • Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended Phox Homology (PX) Domain Critical for Inhibition of SNX10-induced Vacuolation, Jinxin Xu, Tingting Xu, Bin Wu, Yinghua Ye, Xiaojuan You, Xiaodong Shu, Duanqing Pei, Jinsong Liu, 2012
表观遗传学 调控 发育 癌症 机制 囊泡运输 信号转导 生物大分子 疾病 治疗

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