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熊兵
Medical School
中国科学院大学
上海
Language: 中文, 英语
Contact
药物设计 化学合成 药理学 药物化学 有机化合物 抑制剂 核磁共振 基于片段的先导发现 激酶-配体相互作用 评分函数
Areas of Focus
  • 药物化学
  • 有机化学
Academic Background & Achievements
  • 研究生 - 博士
Publications
  • Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors, Hu, Jianping, Wang, Xin, Chen, Lin, Huang, Min, Tang, Wei, Zuo, Jianping, Liu, YuChih, Shi, Zhe, Liu, Rongfeng, Shen, Jingkang, Xiong, Bing, 2016
  • NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds, Yu, Junlan, Chen, Tiantian, Zhou, Chen, Lian, Fulin, Tang, Xulong, Wen, Yi, Shen, Jingkang, Xu, Yechun, Xiong, Bing, Zhang, Naixia, 2016
  • Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors, Tong-chao LIU, Xia PENG, Yu-chi MA, Yin-chun JI, Dan-qi CHEN, Ming-yue ZHENG, Dong-mei ZHAO, Mao-sheng CHENG, Mei-yu GENG, Jing-kang SHEN, Jing AI, Bing XIONG, 2016
  • Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity, Bing Xiong, 2015
  • Design and Optimization of a Series of 1-Sulfonylpyrazolo4,3-bpyridines as Selective c-Met Inhibitors, Ma, Yuchi, Sun, Guangqiang, Chen, Danqi, Peng, Xia, Chen, YueLei, Su, Yi, Ji, Yinchun, Liang, Jin, Wang, Xin, Chen, Lin, Ding, Jian, Xiong, Bing, Ai, Jing, Geng, Meiyu, Shen, Jingkang, 2015
  • Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization, Zhao, Lele, Wang, Yingqing, Cao, Danyan, Chen, Tiantian, Wang, Qi, Li, Yanlian, Xu, Yechun, Zhang, Naixia, Wang, Xin, Chen, Danqi, Chen, Lin, Chen, YueLei, Xia, Guangxin, Shi, Zhe, Liu, YuChih, Lin, Yijyun, Miao, Zehong, Shen, Jingkang, Xiong, Bing, 2015
  • Knowledge-based scoring functions in drug design: 2. Can the knowledge base be enriched?, Shen Qiancheng, Xiong Bing, Zheng Mingyue, Luo Xiaomin, Luo Cheng, Liu Xian, Du Yun, Li Jing, Zhu Weiliang, Shen Jingkang, Jiang Hualiang, 2011
  • Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor, Fong, Desiree H, Xiong, Bing, Hwang, Jiyoung, Berghuis, Albert M, 2011
  • Knowledge-Based Scoring Functions in Drug Design. 1. Developing a Target-Specific Method for Kinase-Ligand Interactions, Xue, Mengzhu, Zheng, Mingyue, Xiong, Bing, Li, Yanlian, Jiang, Hualiang, Shen, Jingkang, 2010
  • BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server, Xiong, Bing, Wu, Jie, Burk, David L, Xue, Mengzhu, Jiang, Hualiang, Shen, Jingkang, 2010
  • ScafBank: a public comprehensive Scaffold database to support molecular hopping, Yan, Bibo, Xue, Mengzhu, Xiong, Bing, Liu, Ke, Hu, Dingyu, Shen, Jingkang, 2009
  • The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation, Xiong, Bing, Burk, David L, Shen, Jianhua, Luo, Xiaomin, Liu, Hong, Shen, Jingkang, Berghuis, Albert M, 2008
  • DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks, Xiong, Bing, Liu, Ke, Wu, Jie, Burk, David L, Jiang, Hualiang, Shen, Jingkang, 2008
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