Professor | 熊兵 | 数字化转型顾问

Name	熊兵
Contact Information	bxiong@mail.shcnc.ac.cn
Language ability	中文, 英语
Province	上海

Name

熊兵

Contact Information

bxiong@mail.shcnc.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	研究生 - 博士

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

研究生 - 博士

Areas of Focus	药物化学有机化学
Publications	Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors, Hu, Jianping, Wang, Xin, Chen, Lin, Huang, Min, Tang, Wei, Zuo, Jianping, Liu, YuChih, Shi, Zhe, Liu, Rongfeng, Shen, Jingkang, Xiong, Bing, 2016 NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds, Yu, Junlan, Chen, Tiantian, Zhou, Chen, Lian, Fulin, Tang, Xulong, Wen, Yi, Shen, Jingkang, Xu, Yechun, Xiong, Bing, Zhang, Naixia, 2016 Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors, Tong-chao LIU, Xia PENG, Yu-chi MA, Yin-chun JI, Dan-qi CHEN, Ming-yue ZHENG, Dong-mei ZHAO, Mao-sheng CHENG, Mei-yu GENG, Jing-kang SHEN, Jing AI, Bing XIONG, 2016 Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity, Bing Xiong, 2015 Design and Optimization of a Series of 1-Sulfonylpyrazolo4,3-bpyridines as Selective c-Met Inhibitors, Ma, Yuchi, Sun, Guangqiang, Chen, Danqi, Peng, Xia, Chen, YueLei, Su, Yi, Ji, Yinchun, Liang, Jin, Wang, Xin, Chen, Lin, Ding, Jian, Xiong, Bing, Ai, Jing, Geng, Meiyu, Shen, Jingkang, 2015 Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization, Zhao, Lele, Wang, Yingqing, Cao, Danyan, Chen, Tiantian, Wang, Qi, Li, Yanlian, Xu, Yechun, Zhang, Naixia, Wang, Xin, Chen, Danqi, Chen, Lin, Chen, YueLei, Xia, Guangxin, Shi, Zhe, Liu, YuChih, Lin, Yijyun, Miao, Zehong, Shen, Jingkang, Xiong, Bing, 2015 Knowledge-based scoring functions in drug design: 2. Can the knowledge base be enriched?, Shen Qiancheng, Xiong Bing, Zheng Mingyue, Luo Xiaomin, Luo Cheng, Liu Xian, Du Yun, Li Jing, Zhu Weiliang, Shen Jingkang, Jiang Hualiang, 2011 Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor, Fong, Desiree H, Xiong, Bing, Hwang, Jiyoung, Berghuis, Albert M, 2011 Knowledge-Based Scoring Functions in Drug Design. 1. Developing a Target-Specific Method for Kinase-Ligand Interactions, Xue, Mengzhu, Zheng, Mingyue, Xiong, Bing, Li, Yanlian, Jiang, Hualiang, Shen, Jingkang, 2010 BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server, Xiong, Bing, Wu, Jie, Burk, David L, Xue, Mengzhu, Jiang, Hualiang, Shen, Jingkang, 2010 ScafBank: a public comprehensive Scaffold database to support molecular hopping, Yan, Bibo, Xue, Mengzhu, Xiong, Bing, Liu, Ke, Hu, Dingyu, Shen, Jingkang, 2009 The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation, Xiong, Bing, Burk, David L, Shen, Jianhua, Luo, Xiaomin, Liu, Hong, Shen, Jingkang, Berghuis, Albert M, 2008 DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks, Xiong, Bing, Liu, Ke, Wu, Jie, Burk, David L, Jiang, Hualiang, Shen, Jingkang, 2008

Areas of Focus

药物化学
有机化学

Publications

Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors, Hu, Jianping, Wang, Xin, Chen, Lin, Huang, Min, Tang, Wei, Zuo, Jianping, Liu, YuChih, Shi, Zhe, Liu, Rongfeng, Shen, Jingkang, Xiong, Bing, 2016
NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds, Yu, Junlan, Chen, Tiantian, Zhou, Chen, Lian, Fulin, Tang, Xulong, Wen, Yi, Shen, Jingkang, Xu, Yechun, Xiong, Bing, Zhang, Naixia, 2016
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors, Tong-chao LIU, Xia PENG, Yu-chi MA, Yin-chun JI, Dan-qi CHEN, Ming-yue ZHENG, Dong-mei ZHAO, Mao-sheng CHENG, Mei-yu GENG, Jing-kang SHEN, Jing AI, Bing XIONG, 2016
Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity, Bing Xiong, 2015
Design and Optimization of a Series of 1-Sulfonylpyrazolo4,3-bpyridines as Selective c-Met Inhibitors, Ma, Yuchi, Sun, Guangqiang, Chen, Danqi, Peng, Xia, Chen, YueLei, Su, Yi, Ji, Yinchun, Liang, Jin, Wang, Xin, Chen, Lin, Ding, Jian, Xiong, Bing, Ai, Jing, Geng, Meiyu, Shen, Jingkang, 2015
Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization, Zhao, Lele, Wang, Yingqing, Cao, Danyan, Chen, Tiantian, Wang, Qi, Li, Yanlian, Xu, Yechun, Zhang, Naixia, Wang, Xin, Chen, Danqi, Chen, Lin, Chen, YueLei, Xia, Guangxin, Shi, Zhe, Liu, YuChih, Lin, Yijyun, Miao, Zehong, Shen, Jingkang, Xiong, Bing, 2015
Knowledge-based scoring functions in drug design: 2. Can the knowledge base be enriched?, Shen Qiancheng, Xiong Bing, Zheng Mingyue, Luo Xiaomin, Luo Cheng, Liu Xian, Du Yun, Li Jing, Zhu Weiliang, Shen Jingkang, Jiang Hualiang, 2011
Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor, Fong, Desiree H, Xiong, Bing, Hwang, Jiyoung, Berghuis, Albert M, 2011
Knowledge-Based Scoring Functions in Drug Design. 1. Developing a Target-Specific Method for Kinase-Ligand Interactions, Xue, Mengzhu, Zheng, Mingyue, Xiong, Bing, Li, Yanlian, Jiang, Hualiang, Shen, Jingkang, 2010
BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server, Xiong, Bing, Wu, Jie, Burk, David L, Xue, Mengzhu, Jiang, Hualiang, Shen, Jingkang, 2010
ScafBank: a public comprehensive Scaffold database to support molecular hopping, Yan, Bibo, Xue, Mengzhu, Xiong, Bing, Liu, Ke, Hu, Dingyu, Shen, Jingkang, 2009
The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation, Xiong, Bing, Burk, David L, Shen, Jianhua, Luo, Xiaomin, Liu, Hong, Shen, Jingkang, Berghuis, Albert M, 2008
DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks, Xiong, Bing, Liu, Ke, Wu, Jie, Burk, David L, Jiang, Hualiang, Shen, Jingkang, 2008

药物设计化学合成药理学药物化学有机化合物抑制剂核磁共振基于片段的先导发现激酶-配体相互作用评分函数

董春娥 - 武汉大学

Area of Focus
药物化学 | 合成 | 有机化学 | 碳-杂键 | 不对称催化 | 仿生学 | 离子通道 | 化学合成 | 研究 | 药品

邹有全 - 武汉大学

陈铁根 - 中国科学院大学

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