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张晓明
Medical School
中国科学院大学
上海
Language: 中文, 英语, 法语
Contact
精准免疫学 流式细胞术 多光谱成像 免疫细胞组学 转录组学 表观遗传组学 计算生物学 感染性疾病 肿瘤 自身免疫疾病
Areas of Focus
  • 人类重大疾病的精准免疫学研究
  • B细胞的发育和功能研究
Work Experience
  • 2012-02 至今 - 中科院上海巴斯德研究所 - 研究员
  • 2007-10 至 2012-01 - 法国巴斯德研究所 - 博士后
Academic Background & Achievements
  • 2004-10 至 2007-09 博士: 法国巴黎第六大学
  • 教育部高等学校科学研究优秀成果奖, 二等奖, 2009
Publications
  • A blueprint for tumor-infiltrating B cells across human cancers, Jiaqiang Ma, Yingcheng Wu, Lifeng Ma, Jia Fan, Guoji Guo, Xiaoming Zhang, Qiang Gao, 2024
  • Neutrophil profiling illuminates anti-tumor antigen-presenting potency, Yingcheng Wu, Jiaqiang Ma, Xupeng Yang, Jia Fan, Xiaoming Zhang, Qiang Gao, 2024
  • A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy, Meng, Lu, Zha, Jialu, Zhou, Bingjie, Cao, Long, Jiang, Congli, Zhu, Yuanfei, Li, Teng, Lu, Lu, Zhang, Junqi, Yang, Heng, Feng, Jian, Gu, Zhifeng, Tang, Hong, Jiang, Lubin, Li, Dianfan, Lavillette, Dimitri, Zhang, Xiaoming, 2023
  • Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage, Bao, Shihua, Chen, Zechuan, Qin, Dengke, Xu, Huihui, Deng, Xujing, Zhang, Ruixiu, Ma, Jiaqiang, Lu, Zhouping, Jiang, Shan, Zhang, Xiaoming, 2023
  • Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level, Wu, Yingcheng, Yang, Shuaixi, Ma, Jiaqiang, Chen, Zechuan, Song, Guohe, Rao, Dongning, Cheng, Yifei, Huang, Siyuan, Liu, Yifei, Jiang, Shan, Liu, Jinxia, Huang, Xiaowu, Wang, Xiaoying, Qiu, Shuangjian, Xu, Jianmin, Xi, Ruibin, Bai, Fan, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Gao, Qiang, 2022
  • Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+dermatomyositis with therapeutic implications, Ye, Yan, Chen, Zechuan, Jiang, Shan, Jia, Fengyun, Li, Teng, Lu, Xia, Xue, Jing, Lian, Xinyue, Ma, Jiaqiang, Hao, Pei, Lu, Liangjing, Ye, Shuang, Shen, Nan, Bao, Chunde, Fu, Qiong, Zhang, Xiaoming, 2022
  • Two Distinct Immune Cell Signatures Predict the Clinical Outcomes in Patients With Amyopathic Dermatomyositis With Interstitial Lung Disease, Ye, Yan, Zhang, Xueliang, Li, Teng, Ma, Jiaqiang, Wang, Ran, Wu, Chunmei, Wang, Runci, Bao, Chunde, Ye, Shuang, Shen, Nan, Guo, Qiang, Fu, Qiong, Zhang, Xiaoming, 2022
  • Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression, Song, Guohe, Shi, Yang, Zhang, Meiying, Goswami, Shyamal, Afridi, Saifullah, Meng, Lu, Ma, Jiaqiang, Chen, Yi, Lin, Youpei, Zhang, Juan, Liu, Yuming, Jin, Zijie, Yang, Shuaixi, Rao, Dongning, Zhang, Shu, Ke, Aiwu, Wang, Xiaoying, Cao, Ya, Zhou, Jian, Fan, Jia, Zhang, Xiaoming, Xi, Ruibin, Gao, Qiang, 2020
  • Highly immunosuppressive HLADR(hi) regulatory T cells are associated with unfavorable outcomes in cervical squamous cell carcinoma, Yang, Huijuan, Ye, Shuang, Goswami, Shyamal, Li, Teng, Wu, Jingwen, Cao, Chunmei, Ma, Jiaqiang, Lu, Bin, Pei, Xuan, Chen, Yanan, Yu, Jing, Xu, Huihui, Qiu, Liwei, Afridi, Saifullah, Xiang, Libing, Zhang, Xiaoming, 2020
  • Lupus-associated atypical memory B cells are mTORC1-hyperactivated and functionally dysregulated, Wu, Chunmei, Fu, Qiong, Guo, Qiang, Chen, Sheng, Goswami, Shyamal, Sun, Shuhui, Li, Teng, Cao, Xingjian, Chu, Fuying, Chen, Zechuan, Liu, Mei, Liu, Yuanhua, Fu, Ting, Hao, Pei, Hao, Yi, Shen, Nan, Bao, Chunde, Zhang, Xiaoming, 2019
Awards
  • 教育部高等学校科学研究优秀成果奖, 二等奖, 2009
Post a Project

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