Professor | 于坤千 | 数字化转型顾问

Name

于坤千

Contact Information

yukunqian@simm.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2002-07到2004-07 博士后: 中国科学院上海生科院 1997-09到2002-07 博士: 吉林大学
Work Experience	2011-10到现在 - 中国科学院上海药物所 - 研究员 2004-07到2011-09 - 中国科学院上海药物所 - 副研究员
Awards	卢嘉锡青年人才奖 (2010): 中国科学院

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	抗感染性疾病药物研发分子模拟与药物设计高性能计算应用
Publications	高性能计算在药物设计和分子模拟领域的应用, 于坤千, 2016 Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus, 于坤千, 2016 Progress in Studies of Structure, Mechanism and Antagonists Interaction of GPCR Co-Receptors for HIV, 于坤千, 2014 Exploring the RING-Catalyzed Ubiquitin Transfer Mechanism by MD and QM/MM Calculations., 于坤千, 2014 Induced opening of influenza virus neuraminidaseN2150-loopsuggestsan important role in inhibitor binding, 于坤千, 2013 How Does Influenza Virus A Escape from Amantadine, 于坤千, 2010 Why are oseltamivir and zanamivir effective to the newly emerged influenza A virus (A/H1N1), 于坤千, 2009 Current strategies for the discovery of K+ channel modulators, 于坤千, 2009 Discovery of a novel CCR5 antagonist lead compound through fragment assembly, 于坤千, 2008 Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase, 于坤千, 2007

Areas of Focus

抗感染性疾病药物研发
分子模拟与药物设计
高性能计算应用

Publications

高性能计算在药物设计和分子模拟领域的应用, 于坤千, 2016
Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus, 于坤千, 2016
Progress in Studies of Structure, Mechanism and Antagonists Interaction of GPCR Co-Receptors for HIV, 于坤千, 2014
Exploring the RING-Catalyzed Ubiquitin Transfer Mechanism by MD and QM/MM Calculations., 于坤千, 2014
Induced opening of influenza virus neuraminidaseN2150-loopsuggestsan important role in inhibitor binding, 于坤千, 2013
How Does Influenza Virus A Escape from Amantadine, 于坤千, 2010
Why are oseltamivir and zanamivir effective to the newly emerged influenza A virus (A/H1N1), 于坤千, 2009
Current strategies for the discovery of K+ channel modulators, 于坤千, 2009
Discovery of a novel CCR5 antagonist lead compound through fragment assembly, 于坤千, 2008
Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase, 于坤千, 2007

药物研发感染性疾病分子模拟药物设计高性能计算计算生物学药物生物技术模拟计算化学生物信息学

徐志建 - 中国科学院大学

张乃霞 - 中国科学院大学

朱维良 - 中国科学院大学

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