Areas of Focus
- 抗感染性疾病药物研发
- 分子模拟与药物设计
- 高性能计算应用
Work Experience
- 2011-10到现在 - 中国科学院上海药物所 - 研究员
- 2004-07到2011-09 - 中国科学院上海药物所 - 副研究员
Academic Background & Achievements
- 2002-07到2004-07 博士后: 中国科学院上海生科院
- 1997-09到2002-07 博士: 吉林大学
Publications
- 高性能计算在药物设计和分子模拟领域的应用, 于坤千, 2016
- Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus, 于坤千, 2016
- Progress in Studies of Structure, Mechanism and Antagonists Interaction of GPCR Co-Receptors for HIV, 于坤千, 2014
- Exploring the RING-Catalyzed Ubiquitin Transfer Mechanism by MD and QM/MM Calculations., 于坤千, 2014
- Induced opening of influenza virus neuraminidaseN2150-loopsuggestsan important role in inhibitor binding, 于坤千, 2013
- How Does Influenza Virus A Escape from Amantadine, 于坤千, 2010
- Why are oseltamivir and zanamivir effective to the newly emerged influenza A virus (A/H1N1), 于坤千, 2009
- Current strategies for the discovery of K+ channel modulators, 于坤千, 2009
- Discovery of a novel CCR5 antagonist lead compound through fragment assembly, 于坤千, 2008
- Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase, 于坤千, 2007
Awards
- 卢嘉锡青年人才奖 (2010): 中国科学院
