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陈贵泉
Medical School
南京大学
江苏
Language: 英语, 中文
神经干细胞
胶质前体细胞
分子机制
神经退行性疾病
阿尔茨海默病
药物筛选
细胞生物学
遗传学
神经科学
疾病机制
Areas of Focus
- 神经干细胞和胶质前体细胞命运决定的分子机制
- 神经退行死亡的分子机制
- AD药物的筛选及作用机制的研究
Academic Background & Achievements
- 2005 - 神经科学博士: 爱丁堡大学
- 研究神经系统相关疾病的机理
Publications
- Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but not into basal progenitors in the developing hippocampus, Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji M, Chen G, 2022
- A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice, Teng X, Hu P, Chen Y, Zang Y, Ye X, Ou J, Chen G, Shi YS, 2022
- Akt regulates Sox10 expression to control oligodendrocyte differentiation via phosphorylating FoxO1, Wang H, Liu M, Ye Z, Zhou C, Bi H, Wang L, Zhang C, Fu H, Shen Y, Yang J, Hu Y, Chen G, 2021
- Pen-2 negatively regulates the differentiation of oligodendrocyte precursor cells into astrocytes in the central nervous system, Hou J, Bi H, Ye Z, Huang W, Zou G, Zou X, Shi Y, Shen Y, Ma Q, Kirchhoff F, Hu Y, Chen G, 2021
- Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system, Wang H, Liu M, Zou G, Wang L, Duan W, He X, Ji M, Zou X, Hu Y, Yang J, Chen G, 2021
- Neuron-specific deletion of presenilin enhancer 2 causes progressive astrogliosis and age-related neurodegeneration in the cortex independent of the Notch signaling, Bi H, Zhou C, Zhang Y, Cai X, Ji M, Yang J, Chen G, Hu Y, 2021
- In vivo brain imaging of amyloid-β aggregates in Alzheimer's disease with a near-infrared fluorescent probe, Wu J, Shao C, Ye X, Di X, Li D, Zhao H, Zhang B, Chen G, Liu H-K, Qian Y, 2021
- Klf2-Vav1-Rac1 axis promotes axon regeneration after peripheral nerve injury, Wang Q, Gong L, Mao S, Yao C, Liu M, Wang Y, Yang J, Yu B, Chen G, Gu X, 2021
- Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis, Shao C, Yuan J, Liu Y, Wang X, Gu J, Chen G, Zhang B, Liu H, Zhao J, Zhu H, Qian Y, 2020
- Loss of PP2A disrupts the retention of radial glial progenitors in the telencephalic niche to impair the generation of late-born neurons during cortical development, Huang C, Liu T, Wang Q, Hou W, Zhou C, Song Z, Shi YS, Gao X, Chen G, Yin Z, Hu Y, 2020
- Aβ-sheet-targeted theranostic agent for diagnosing and preventing aggregation of pathogenic peptides in Alzheimer’s disease, Ma X, Wang Y, Hua J, Xu C, Yang T, Yuan J, Chen G, Guo Z, Wang X, 2020
- Conditional inactivation of Pen-2 in the developing neocortex leads to rapid switch of apical progenitors to basal progenitors, Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, Zou X, Shi Y, Zheng Y, Lu J, Chen G, 2019
