Professor | 祝颖慧 | 数字化转型顾问

Name	祝颖慧
Contact Information	zhuyinghui@tongji.edu.cn
Language ability	中文, 英语
Province	上海

Name

祝颖慧

Contact Information

zhuyinghui@tongji.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	同济大学
Faculty	Life Sciences
Academic Background & Achievements	2010.9-2016.1 理学博士：中国科学院北京基因组研究所入选上海市海外高层次人才计划
Work Experience	2023.2至今 - 同济大学附属东方医院转化医学中心；研究员 2022.9至今 - 同济大学生命科学与技术学院/同济大学高等研究院；特聘研究员 2016.3-2020 - 美国希望之城国家医疗中心；博士后/在职科学家

University/Lab Affiliation and Title

同济大学

Faculty

Life Sciences

Academic Background & Achievements

2010.9-2016.1 理学博士：中国科学院北京基因组研究所
入选上海市海外高层次人才计划

Work Experience

2023.2至今 - 同济大学附属东方医院转化医学中心；研究员
2022.9至今 - 同济大学生命科学与技术学院/同济大学高等研究院；特聘研究员
2016.3-2020 - 美国希望之城国家医疗中心；博士后/在职科学家

Areas of Focus	急性白血病发病及耐药机制白血病的靶向免疫疗法开发
Publications	Phosphoproteomic Characterization and Kinase Signature Predict Response to Venetoclax plus 3+7 Chemotherapy in AML, Jin J, Hou SY, Yao YY, Mao LP, Yang M, Tong HY, Zeng T, Huang JY, Zhu YH, Wang HF, 2023 Identification of a novel NPM1 mutation in acute myeloid leukemia, Yao YY, Lin XJ, Wang C, Gu Y, Jin J, Zhu YH, Wang HF, 2023 CD38-directed, single-chain T cell-engager targets leukemia stem cells through IFNγ-induced CD38 expression, Murtadha M, Park M, Zhu YH, Caserta E, Napolitano O, Tandoh T, Moloudizargari M, Pozhitkov A, Singer M, Dona AA, Vahed H, Gonzalez A, Ly K, Ouyang C, Sanchez JF, Nigam L, Chowdhury A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams JC, Pichiorri F, 2024 Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer, Zhu YH, He X, Li S, Gan YC, Li Z, Wang HY, et al., and Li L, 2022 Targeting PRMT1-Mediated FLT3 Methylation Disrupts Maintenance of MLL- rearranged Acute Lymphoblastic Leukemia, Zhu YH, He X, Lin YC, Dong HJ, Zhang L, Chen XC, Wang ZH, Shen YD, Li M, Wang HY, Sun J, Nguyen LX, Zhang H, Jiang WJ, Yang YZ, Chen JJ, Müschen M, Chen CW, Konopleva MY, Sun WL, Jin J, Carlesso N, Marcucci G, Luo Y, and Li L, 2019 A Comprehensive Proteomics Analysis Reveals a Secretory Path- and Status-Dependent Signature of Exosomes Released from Tumor-Associated Macrophages, Zhu YH, Chen XW, Pan QF, Wang Y, Su SY, Jiang CC, Li Y, Xu NZ, Wu L, Lou XM, and Liu SQ, 2015 mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances, Chen XW, Zhu YH, Wang ZH, Zhu HS, Pan QF, Su SY, et al., Liu SQ, 2016 SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu YH, Ding ZH, Dong HJ, Feng YM, Du J, Wang HY, Wu XW, Zhang L, Yu XC, Lin A, McDonald T, Zhao DD, Wu H, Hua WK, Zhang B, Feng LF, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Peter DA, Jacqueline B, Andrea P, Samer K, Marcin K, Pichiorri F, Kuo YH, Carlesso N, Guido M, Jin HC, and Li L, 2018

Areas of Focus

急性白血病发病及耐药机制
白血病的靶向免疫疗法开发

Publications

Phosphoproteomic Characterization and Kinase Signature Predict Response to Venetoclax plus 3+7 Chemotherapy in AML, Jin J, Hou SY, Yao YY, Mao LP, Yang M, Tong HY, Zeng T, Huang JY, Zhu YH, Wang HF, 2023
Identification of a novel NPM1 mutation in acute myeloid leukemia, Yao YY, Lin XJ, Wang C, Gu Y, Jin J, Zhu YH, Wang HF, 2023
CD38-directed, single-chain T cell-engager targets leukemia stem cells through IFNγ-induced CD38 expression, Murtadha M, Park M, Zhu YH, Caserta E, Napolitano O, Tandoh T, Moloudizargari M, Pozhitkov A, Singer M, Dona AA, Vahed H, Gonzalez A, Ly K, Ouyang C, Sanchez JF, Nigam L, Chowdhury A, Ghoda L, Li L, Zhang B, Krishnan A, Marcucci G, Williams JC, Pichiorri F, 2024
Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer, Zhu YH, He X, Li S, Gan YC, Li Z, Wang HY, et al., and Li L, 2022
Targeting PRMT1-Mediated FLT3 Methylation Disrupts Maintenance of MLL- rearranged Acute Lymphoblastic Leukemia, Zhu YH, He X, Lin YC, Dong HJ, Zhang L, Chen XC, Wang ZH, Shen YD, Li M, Wang HY, Sun J, Nguyen LX, Zhang H, Jiang WJ, Yang YZ, Chen JJ, Müschen M, Chen CW, Konopleva MY, Sun WL, Jin J, Carlesso N, Marcucci G, Luo Y, and Li L, 2019
A Comprehensive Proteomics Analysis Reveals a Secretory Path- and Status-Dependent Signature of Exosomes Released from Tumor-Associated Macrophages, Zhu YH, Chen XW, Pan QF, Wang Y, Su SY, Jiang CC, Li Y, Xu NZ, Wu L, Lou XM, and Liu SQ, 2015
mTORC1 alters the expression of glycolytic genes by regulating KPNA2 abundances, Chen XW, Zhu YH, Wang ZH, Zhu HS, Pan QF, Su SY, et al., Liu SQ, 2016
SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu YH, Ding ZH, Dong HJ, Feng YM, Du J, Wang HY, Wu XW, Zhang L, Yu XC, Lin A, McDonald T, Zhao DD, Wu H, Hua WK, Zhang B, Feng LF, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Peter DA, Jacqueline B, Andrea P, Samer K, Marcin K, Pichiorri F, Kuo YH, Carlesso N, Guido M, Jin HC, and Li L, 2018

白血病急性发病机制耐药机制靶向免疫疗法开发临床应用多维组学

张巍 - 华东师范大学

伏学坤 - 南方科技大学

赵春华 - 上海大学

Area of Focus
干细胞 | 生物学 | 临床应用 | 间充质 | 转化 | 研究 | 开发 | 治疗 | 再生医学 | 细胞系统

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