Professor | 周兆才 | 数字化转型顾问

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Name	周兆才
Contact Information	zhouzhaocai@fudan.edu.cn
Language ability	中文, 英文
Province	上海

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Name

周兆才

Contact Information

zhouzhaocai@fudan.edu.cn

Language ability

中文, 英文

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Life Sciences
Academic Background & Achievements	2004 博士: 中国科学技术大学 2009 研究员: 中国科学院上海生化与细胞所 2014 杰出青年科技创新人才: 中国科学院 2017 特聘研究员: 中国科学院分子细胞科学卓越创新中心 2020 特聘教授: 复旦大学
Work Experience	2004-2009 - 宾夕法尼亚大学 - 博士后研究员 2009-2014 - 中国科学院上海生化与细胞所 - 研究员 2017-2020 - 中国科学院分子细胞科学卓越创新中心 - 特聘研究员 2020-至今 - 复旦大学 - 特聘教授
Awards	2014: 中国科学院杰出青年科技创新人才 2017: 国家自然科学基金委医学部“杰青”资助

University/Lab Affiliation and Title

复旦大学

Faculty

Life Sciences

Academic Background & Achievements

2004 博士: 中国科学技术大学
2009 研究员: 中国科学院上海生化与细胞所
2014 杰出青年科技创新人才: 中国科学院
2017 特聘研究员: 中国科学院分子细胞科学卓越创新中心
2020 特聘教授: 复旦大学

Work Experience

2004-2009 - 宾夕法尼亚大学 - 博士后研究员
2009-2014 - 中国科学院上海生化与细胞所 - 研究员
2017-2020 - 中国科学院分子细胞科学卓越创新中心 - 特聘研究员
2020-至今 - 复旦大学 - 特聘教授

Awards

2014: 中国科学院杰出青年科技创新人才
2017: 国家自然科学基金委医学部“杰青”资助

Areas of Focus	肿瘤发生及免疫应答的分子细胞信号机制
Publications	A TNFR2-hnRNPK axis promotes primary liver cancer development via activation of YAP signaling in hepatic progenitor cells, Meng Y, Zhao Q, An L, Jiao S, Li R, Sang Y, Liao J, Nie P, Wen F, Ju J et al., 2021 Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer, Tang Y, Fang G, Guo F, Zhang H, Chen X, An L, Chen M, Zhou L, Wang W, Ye T et al., 2020 MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway, An L, Nie P, Chen M, Tang Y, Zhang, H, Guan J, Cao Z, Hou C, Wang W, Zhao Y et al., 2020 Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling, Xu J, Tang Y, Sheng X, Tian Y, Deng M, Du S, Lv C, Li G, Pan Y, Song Y et al., 2020 Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling, Tang Y, Chen M, Zhou L, Ma J, Li Y, Zhang H, Shi Z, Xu Q, Zhang X, Gao Z et al., 2019 TRAF3-interacting JNK-activating modulator promotes inflammation by stimulating translocation of Toll-like receptor 4 to lipid rafts, Li Y, Guan J, Wang W, Hou C, Zhou L, Ma J, Cheng Y, Jiao S, Zhou Z, 2019 Targeting IRF3 as a YAP agonist therapy against gastric cancer, Jiao S, Guan J, Chen M, Wang W, Li C, Wang Y, Cheng Y, Zhou Z, 2018 The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer, Chen M, Zhang H, Shi Z, Li Y, Zhang X, Gao Z, Zhou L, Ma J, Xu Q, Guan J et al., 2018 DNA-binding mechanism of the Hippo pathway transcription factor TEAD4, Shi Z, He F, Chen M, Hua L, Wang W, Jiao S, Zhou Z, 2017 VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer, Jiao S, Li C, Hao Q, Miao H, Zhang L, Li

Areas of Focus

肿瘤发生及免疫应答的分子细胞信号机制

Publications

A TNFR2-hnRNPK axis promotes primary liver cancer development via activation of YAP signaling in hepatic progenitor cells, Meng Y, Zhao Q, An L, Jiao S, Li R, Sang Y, Liao J, Nie P, Wen F, Ju J et al., 2021
Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer, Tang Y, Fang G, Guo F, Zhang H, Chen X, An L, Chen M, Zhou L, Wang W, Ye T et al., 2020
MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway, An L, Nie P, Chen M, Tang Y, Zhang, H, Guan J, Cao Z, Hou C, Wang W, Zhao Y et al., 2020
Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling, Xu J, Tang Y, Sheng X, Tian Y, Deng M, Du S, Lv C, Li G, Pan Y, Song Y et al., 2020
Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling, Tang Y, Chen M, Zhou L, Ma J, Li Y, Zhang H, Shi Z, Xu Q, Zhang X, Gao Z et al., 2019
TRAF3-interacting JNK-activating modulator promotes inflammation by stimulating translocation of Toll-like receptor 4 to lipid rafts, Li Y, Guan J, Wang W, Hou C, Zhou L, Ma J, Cheng Y, Jiao S, Zhou Z, 2019
Targeting IRF3 as a YAP agonist therapy against gastric cancer, Jiao S, Guan J, Chen M, Wang W, Li C, Wang Y, Cheng Y, Zhou Z, 2018
The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer, Chen M, Zhang H, Shi Z, Li Y, Zhang X, Gao Z, Zhou L, Ma J, Xu Q, Guan J et al., 2018
DNA-binding mechanism of the Hippo pathway transcription factor TEAD4, Shi Z, He F, Chen M, Hua L, Wang W, Jiao S, Zhou Z, 2017
VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer, Jiao S, Li C, Hao Q, Miao H, Zhang L, Li

肿瘤发生免疫应答分子信号细胞信号胃癌靶向治疗生物标志物器官生长稳态免疫治疗

陈丹英 - 北京大学

焦石 - 复旦大学

周兆才 - 复旦大学

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