张诗宜
Biomedical Engineering
上海交通大学
上海
Language: 英语, 汉语
Contact
抗癌 副作用 口服药物 不吸收 临床研究 药物传递 胃肠道 毒性 化疗 创新
Areas of Focus
  • 抗癌药物的副作用
  • 口服不吸收药物
Work Experience
  • 2013-2016 - 麻省理工学院 - 博士后研究员
  • 2016至今 - 上海交通大学 - 长聘副教授
Academic Background & Achievements
  • 2004-2008 本科:北京大学
  • 2008-2013 博士:华盛顿大学圣路易斯
  • 2013-2016 博士后研究:麻省理工学院
  • 国家级青年人才项目获得者
Publications
  • A Transformable Mucoadhesive Microgel Network for Noninvasive Multimodal Imaging and Radioprotection of a Large Area of the Gastrointestinal Tract, 张, S.*, 2023
  • CDK4/6 inhibitor modulating active and quiescent intestinal stem cells for prevention of chemotherapy-induced diarrhea, 张, S.*, 2023
  • DNA damage-mediated cellular senescence promotes hand–foot syndrome that can be relieved by thymidine prodrug, 张, S.*, 2022
  • Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil, 张, S.*, 2022
  • Challenging the fundamental conjectures in nanoparticle drug delivery for chemotherapy treatment of solid cancers, 张, S.*, 2022
  • Oral Supramolecular Adsorbent for Preventing Chemo-Induced Gastrointestinal Mucositis & Microbial Dysbiosis and for Enhancing Chemoimmunotherapy, 张, S.*, 2022
  • Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy, 张, S.*, 2022
  • Prophylactic effect of nitric oxide donors on rat models of EGFR inhibitors induced-cutaneous toxicities, 张, S.*, 2022
  • Nitric Oxide in Multikinase Inhibitor-induced Hand-Foot Skin Reaction, 张, S.*, 2022
  • GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib, 张, S.*, 2021
  • A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise, 张, S.*, 2021
  • Orally administered saccharide-sequestering nanocomplex to manage carbohydrate metabolism disorders, 张, S.*, 2021
  • Oral, Ultra–long-lasting Drug Delivery: Application Toward Malaria Elimination Goals, 张, S.*, 2016
  • A pH-responsive Supramolecular Polymer Gel as an Enteric Elastomer for Use in Gastric Devices, 张, S.*, 2015
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