Areas of Focus
- 生物大分子模拟
- 生物反应机理
- 人工智能方法
Work Experience
- 2012/03-2013/01 北京大学，深圳研究生院/化学生物学与生物技术学院，研究助理
- 2013/02-2016/01 上海交通大学，生命科学技术学院，博士后
- 2016/01-至今，上海交通大学，生命科学技术学院，助理研究员
Academic Background & Achievements
- 2002/09-2006/07 北京大学，化学与分子工程学院，化学专业，本科
- 2006/09-2011/12 北京大学，化学与分子工程学院，物理化学专业，博士
Publications
- Ning Kang, Xiao-Lei Wang*, Yaxue Zhao*, Discovery of small molecule agonists targeting neuropeptide Y4 receptor using homology modeling and virtual screening. Chem Biol Drug Des., 2019, 00: 1–9., Ning Kang, Xiao-Lei Wang*, Yaxue Zhao*, 2019
- Zhang Zhang, Dong Wang*, Xiao-Lei Wang, Yan Xu*, Regulation of ester synthesis activity of Rhizopus Chinensis lipase. Chem. J. Chinese U., 2019, 40: 747–754., Zhang Zhang, Dong Wang*, Xiao-Lei Wang, Yan Xu*, 2019
- Guang Liu, Wencheng Fu, Zhenyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi-Lei Zhao, Zixin Deng, Geng Wu*, Xinyi He*, Structural basis for the recognition of sulfur in phosphorothioated DNA. Nat. Commun., 2018, 9: 4689., Guang Liu, Wencheng Fu, Zhenyi Zhang, Yao He, Hao Yu, Yuli Wang, Xiaolei Wang, Yi-Lei Zhao, Zixin Deng, Geng Wu*, Xinyi He*, 2018
- Chao Zhou, Ting Shi, Yilei Zhao, Xiaolei Wang*, Theoretical analysis of oxygen diffusion in the micro-channels of quinoline oxygenase. Chem. J. Chinese U., 2017, 38: 1813–1821., Chao Zhou, Ting Shi, Yilei Zhao, Xiaolei Wang*, 2017
- Tingting Wu, Qiang Huang, Xiao-Lei Wang, Ting Shi, Linquan Bai, Jingdan Liang, Zhijun Wang, Zixin Deng, Yi-Lei Zhao*, Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA. Sci. Rep., 2017, 7: 42823., Tingting Wu, Qiang Huang, Xiao-Lei Wang, Ting Shi, Linquan Bai, Jingdan Liang, Zhijun Wang, Zixin Deng, Yi-Lei Zhao*, 2017
- Xiong-Ping Chen, Ting Shi, Xiao-Lei Wang, Jitao Wang, Qihua Chen, Linquan Bai, Yi-Lei Zhao*, Theoretical Studies on the Mechanism of Thioesterase-Catalyzed Macrocyclization in Erythromycin Biosynthesis. ACS Catal. 2016, 6: 4369–4378., Xiong-Ping Chen, Ting Shi, Xiao-Lei Wang, Jitao Wang, Qihua Chen, Linquan Bai, Yi-Lei Zhao*, 2016
- Yan-Bing Qi, Xiao-Lei Wang, Ting Shi, Shuchang Liu, Zhen-Hao Xu, Xiqing Li, Xuling Shi, Ping Xu, Yi-Lei Zhao*, Multicomponent kinetic analysis and theoretical studies on the phenolic intermediates in the oxidation of eugenol and isoeugenol catalyzed by laccase. Phys. Chem. Chem. Phys., 2015, 17: 29597–29607., Yan-Bing Qi, Xiao-Lei Wang, Ting Shi, Shuchang Liu, Zhen-Hao Xu, Xiqing Li, Xuling Shi, Ping Xu, Yi-Lei Zhao*, 2015
- Limeng Chen, Xiao-Lei Wang, Ting Shi, Tingting Wu, Zixin Deng, Yi-Lei Zhao*, Theoretical study on the relationship between Rp-phosphorothioation and base-step in S-DNA: based on energetic and structural analysis. J. Phys. Chem. B, 2015, 119: 474–481., Limeng Chen, Xiao-Lei Wang, Ting Shi, Tingting Wu, Zixin Deng, Yi-Lei Zhao*, 2015
- Yanbing Qi, Jiren Zhu, Yaojin Sun, Yun Du, Jianjun Chu, Ting Shi, Yilei Zhao*, Xiaolei Wang*, Theoretical studies of the binding-affinity and reactivity between laccase and phenolic substrates. Chem. J. Chinese U., 2014, 35: 776–783., Yanbing Qi, Jiren Zhu, Yaojin Sun, Yun Du, Jianjun Chu, Ting Shi, Yilei Zhao*, Xiaolei Wang*, 2014
- Xiao-Lei Wang, Jun-Min Quan*, Intermediate-Assisted Multifunctional Catalysis in the Conversion of Flavin to 5,6-Dimethylbenzimidazole by BluB: A Density Functional Theory Study. J. Am. Chem. Soc., 2011, 133: 4079–4091., Xiao-Lei Wang, Jun-Min Quan*, 2011
Awards
- 2018年上海交通大学博士后奖励基金
