Professor | 杨帆 | 数字化转型顾问

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Name

杨帆

Language ability

英语, 中文

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	2006.09-2012.06 加州大学戴维斯分校，生理学博士 2002.09-2006.06 浙江大学，生命科学学士中国神经科学学会离子通道与受体分会委员中国神经科学学会离子通道与受体分会副秘书长中国毒理学会生物毒素专业委员会常委国家优青项目获得者浙江省杰青项目获得者
Work Experience	2012.11-2017.6 - 加州大学戴维斯分校 - 博士后研究员 2017.6-至今 - 浙江大学医学院 - 研究员
Awards	国家优青项目: 获得者浙江省杰青项目: 获得者

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	膜蛋白的功能与动态构象变化基于蛋白质三维结构的生物大分子理性设计
Publications	Structures and mechanisms of the Arabidopsis auxin transporter PIN3, Su NN., Zhu A., Tao X., Ding Z J., Chang S., Ye F., Zhang Y., Zhao C., Chen Q., Wang J., Zhou C Y., Guo Y., Jiao S., Zhang S., Wen H., Ma L., Ye S., Zheng S J., F. Yang, Wu S, Guo JT, 2022 Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands, Su NN., WX. Zhen, H. Zhang, LY. Xu, YT Jin, XY. Chen, C. Zhao, QR. Wang, XY. Wang, SW. Li, H. Wen, W. Yang, JT. Guo, F. Yang, 2022 Structure-guided peptide engineering of a positive allosteric modulator targeting the outer pore of TRPV1 for long-lasting analgesia, Zhang, H., JJ. Lin, YK. Xie, XZ. Song, JY. Sun, BL. Zhang, YK. Qi, ZZ. Xu, F. Yang, 2023 Rational design of a modality-specific inhibitor of TRPM8 channel against oxaliplatin-induced cold allodynia, A. Aierken, YK. Xie, WQ. Dong, A. Apaer, JJ. Lin, ZH. Zhao, SL. Yang, ZZ. Xu, F. Yang, 2021 De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects, Xu, L., Zhang, H., Y. Wang, X. Lu, Z. Zhao, C. Ma, S. Yang, V. Yarov-Yarovoy, YH. Tian, J. Zheng, F. Yang, 2021

Areas of Focus

膜蛋白的功能与动态构象变化
基于蛋白质三维结构的生物大分子理性设计

Publications

Structures and mechanisms of the Arabidopsis auxin transporter PIN3, Su NN., Zhu A., Tao X., Ding Z J., Chang S., Ye F., Zhang Y., Zhao C., Chen Q., Wang J., Zhou C Y., Guo Y., Jiao S., Zhang S., Wen H., Ma L., Ye S., Zheng S J., F. Yang, Wu S, Guo JT, 2022
Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands, Su NN., WX. Zhen, H. Zhang, LY. Xu, YT Jin, XY. Chen, C. Zhao, QR. Wang, XY. Wang, SW. Li, H. Wen, W. Yang, JT. Guo, F. Yang, 2022
Structure-guided peptide engineering of a positive allosteric modulator targeting the outer pore of TRPV1 for long-lasting analgesia, Zhang, H., JJ. Lin, YK. Xie, XZ. Song, JY. Sun, BL. Zhang, YK. Qi, ZZ. Xu, F. Yang, 2023
Rational design of a modality-specific inhibitor of TRPM8 channel against oxaliplatin-induced cold allodynia, A. Aierken, YK. Xie, WQ. Dong, A. Apaer, JJ. Lin, ZH. Zhao, SL. Yang, ZZ. Xu, F. Yang, 2021
De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects, Xu, L., Zhang, H., Y. Wang, X. Lu, Z. Zhao, C. Ma, S. Yang, V. Yarov-Yarovoy, YH. Tian, J. Zheng, F. Yang, 2021

膜蛋白动态构象变化 Trp通道 Trpv1 Trpm8 镇痛蛋白质三维结构生物大分子理性设计离子通道

杨巍 - 浙江大学

张兴 - 浙江大学

Area of Focus
膜蛋白 | 结构 | 功能 | 病原体 | 核糖体 | 病毒 | 感染 | 线粒体 | 离子通道 | 光合作用

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