Professor | 杨章华 | 数字化转型顾问

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Name	杨章华
Contact Information	zhanghuayang@zju.edu.cn
Language ability	中文, 英语
Province	浙江

Upload Avatar (500 x 500)

Name

杨章华

Contact Information

zhanghuayang@zju.edu.cn

Language ability

中文, 英语

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	2016 博士: 厦门大学在国际期刊上发表了15篇论文论文总被引用数超过3200次

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

2016 博士: 厦门大学
在国际期刊上发表了15篇论文
论文总被引用数超过3200次

Areas of Focus	程序性细胞死亡炎症反应天然免疫
Publications	A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade, 杨章华, 吴晓宁, 何鹏, 王晓, 吴杰, 艾涛, 钟春泉, 吴晓, 丛阳, 朱瑞, 李辉, 蔡志勇, 莫文, 韩家淮, 2020 A ZBP1 isoform blocks ZBP1-mediated cell death, 蔡志勇, 吴鹏, 梁浩, 谢一中, 张博翔, 何成龙, 杨成瑞, 李辉, 莫文, 杨章华, 2024 Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity, 吴晓, 杨章华, 吴杰, 韩家淮, 2023 Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to TNF-induced death, 何鹏, 艾涛, 乔明, 杨章华, 韩家淮, 2024 Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases, 吴晓, 杨章华, 郑阳, 吴杰, 韩家淮, 2024 Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, 吴晓宁, 杨章华, 王晓坤, 张宇, 万华, 宋阳, 陈晓, 邵杰, 韩家淮, 2014 Dual ligand engagement for noncanonical inflammasome activation, 杨章华, 韩家淮, 2022 Detection of necroptosis by phospho-MLKL immunohistochemical labeling, 何鹏, 艾涛, 杨章华, 吴杰, 韩家淮, 2021 Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death, 李翔, 张鹏, 尹志, 徐飞, 杨章华, 金杰, 曲杰, 刘志, 齐辉, 姚成, 帅军, 2022 Glycogen synthase kinase 3 drives thymocyte egress by suppressing beta-catenin activation of Akt, 刘成, 马龙, 王勇, 赵杰, 陈鹏, 陈晓, 王勇, 胡阳, 刘阳, 贾翔, 杨章华, 尹翔, 吴杰, 吴松, 郑浩, 马晓, 孙翔, 何阳, 林龙, 傅阳, 廖凯, 周翔, 江山, 傅刚, 唐杰, 韩伟, 陈晓龙, 范伟, 洪阳, 韩家淮, 黄翔, 李伯安, 肖宁, 肖成, 傅刚, 刘文华, 2021 RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes, 李翔, 钟春泉, 吴瑞, 徐翔, 杨章华, 蔡松, 吴晓, 陈晓, 尹志, 何强, 李东, 徐飞, 闫阳, 齐辉, 谢成, 帅军, 韩家淮, 2021 Gut stem cell necroptosis by genome instability triggers bowel inflammation, 王锐, 李辉, 吴杰, 蔡志勇, 李波, 倪华, 邱翔, 陈浩, 刘伟, 杨章华, 刘明, 胡杰, 梁阳, 蓝鹏, 韩家淮, 莫文, 2020 Quantification of Dynamic Protein Interactions and Phosphorylation in LPS Signaling Pathway by SWATH-MS, 吴晓, 杨东, 赵飞, 杨章华, 王东, 乔明, 方阳, 李伟, 吴瑞, 何鹏, 丛阳, 陈成, 胡龙, 闫阳, 谢成, 吴阳, 韩家淮, 钟春泉, 2019 RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, 张宇, 苏松松, 赵山, 杨章, 钟春泉, 陈晓, 蔡强, 杨章华, 黄东, 吴瑞, 韩家淮, 2017 Gasdermin D is an executor of pyroptosis and required for interleukin-1 beta secretion, 何伟, 万华, 胡龙, 陈鹏, 王晓, 黄志, 杨章华, 钟春泉, 韩家淮, 2015

Areas of Focus

程序性细胞死亡
炎症反应
天然免疫

Publications

A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade, 杨章华, 吴晓宁, 何鹏, 王晓, 吴杰, 艾涛, 钟春泉, 吴晓, 丛阳, 朱瑞, 李辉, 蔡志勇, 莫文, 韩家淮, 2020
A ZBP1 isoform blocks ZBP1-mediated cell death, 蔡志勇, 吴鹏, 梁浩, 谢一中, 张博翔, 何成龙, 杨成瑞, 李辉, 莫文, 杨章华, 2024
Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity, 吴晓, 杨章华, 吴杰, 韩家淮, 2023
Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to TNF-induced death, 何鹏, 艾涛, 乔明, 杨章华, 韩家淮, 2024
Bypassing PELO-mediated ATPase activation of the NLR is a common pathogenic cause of NLR-associated autoinflammatory diseases, 吴晓, 杨章华, 郑阳, 吴杰, 韩家淮, 2024
Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, 吴晓宁, 杨章华, 王晓坤, 张宇, 万华, 宋阳, 陈晓, 邵杰, 韩家淮, 2014
Dual ligand engagement for noncanonical inflammasome activation, 杨章华, 韩家淮, 2022
Detection of necroptosis by phospho-MLKL immunohistochemical labeling, 何鹏, 艾涛, 杨章华, 吴杰, 韩家淮, 2021
Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death, 李翔, 张鹏, 尹志, 徐飞, 杨章华, 金杰, 曲杰, 刘志, 齐辉, 姚成, 帅军, 2022
Glycogen synthase kinase 3 drives thymocyte egress by suppressing beta-catenin activation of Akt, 刘成, 马龙, 王勇, 赵杰, 陈鹏, 陈晓, 王勇, 胡阳, 刘阳, 贾翔, 杨章华, 尹翔, 吴杰, 吴松, 郑浩, 马晓, 孙翔, 何阳, 林龙, 傅阳, 廖凯, 周翔, 江山, 傅刚, 唐杰, 韩伟, 陈晓龙, 范伟, 洪阳, 韩家淮, 黄翔, 李伯安, 肖宁, 肖成, 傅刚, 刘文华, 2021
RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes, 李翔, 钟春泉, 吴瑞, 徐翔, 杨章华, 蔡松, 吴晓, 陈晓, 尹志, 何强, 李东, 徐飞, 闫阳, 齐辉, 谢成, 帅军, 韩家淮, 2021
Gut stem cell necroptosis by genome instability triggers bowel inflammation, 王锐, 李辉, 吴杰, 蔡志勇, 李波, 倪华, 邱翔, 陈浩, 刘伟, 杨章华, 刘明, 胡杰, 梁阳, 蓝鹏, 韩家淮, 莫文, 2020
Quantification of Dynamic Protein Interactions and Phosphorylation in LPS Signaling Pathway by SWATH-MS, 吴晓, 杨东, 赵飞, 杨章华, 王东, 乔明, 方阳, 李伟, 吴瑞, 何鹏, 丛阳, 陈成, 胡龙, 闫阳, 谢成, 吴阳, 韩家淮, 钟春泉, 2019
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, 张宇, 苏松松, 赵山, 杨章, 钟春泉, 陈晓, 蔡强, 杨章华, 黄东, 吴瑞, 韩家淮, 2017
Gasdermin D is an executor of pyroptosis and required for interleukin-1 beta secretion, 何伟, 万华, 胡龙, 陈鹏, 王晓, 黄志, 杨章华, 钟春泉, 韩家淮, 2015

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