Professor | 邵璇 | 数字化转型顾问

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Name	邵璇
Contact Information	shaoxuan@ioz.ac.cn
Language ability	中文, 英文
Province	北京市

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Name

邵璇

Contact Information

shaoxuan@ioz.ac.cn

Language ability

中文, 英文

Province

北京市

University/Lab Affiliation and Title	中国科学院
Faculty	Institute of Zoology
Academic Background & Achievements	2006 - 学士学位: 河北大学 2014 - 理学博士: 中国科学院动物研究所成就: 在PNAS、Journal of Pineal Research等期刊发表论文15篇
Work Experience	2021 - 至今 - 中国科学院动物研究所 - 副研究员生殖病理学研究组成员
Awards	国家自然科学基金 - 面上项目国家自然科学基金 - 青年科学基金项目

University/Lab Affiliation and Title

中国科学院

Faculty

Institute of Zoology

Academic Background & Achievements

2006 - 学士学位: 河北大学
2014 - 理学博士: 中国科学院动物研究所
成就: 在PNAS、Journal of Pineal Research等期刊发表论文15篇

Work Experience

2021 - 至今 - 中国科学院动物研究所 - 副研究员
生殖病理学研究组成员

Awards

国家自然科学基金 - 面上项目
国家自然科学基金 - 青年科学基金项目

Areas of Focus	妊娠适应性调节滋养层细胞代谢
Publications	Orchestrated feedback regulation between melatonin and sex hormones involving GPER1-PKA-CREB signaling in the placenta., Shao X#, Yang Y#, Liu Y#, Wang Y#, Zhao Y, Yu X, Liu J, Li YX, Wang YL., 2023 The mystery of the life tree: the placenta., Shao X#, Yu W#, Yang Y#, Wang F, Yu X, Wu H, Ma Y, Cao B, Wang YL., 2022 Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at mid-gestation highlights the defective impacts on fetal health., Chen J#, Du L#, Wang F#, Shao X#, Wang X, Yu W, Bi S, Chen D, Pan X, Zeng S, Huang L, Liang Y, Li Y, Chen R, Xue F, Li X, Wang S, Zhuang M, Liu M, Lin L, Yan H, He F, Yu L, Jiang Q, Xiong Z, Zhang L, Cao B, Wang YL, Chen D., 2022 Placental development and Pregnancy-Associated Diseases., Yu X#, Wu Hong#, Yang Y, Wang F, Wang YL, Shao X., 2022 Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia., Li G#, Wang Y#, Cao G#, Ma Y, Li YX, Zhao Y, Shao X, Wang YL., 2022 Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply., Shao X#, Cao G#, Chen D#, Liu J, Yu B, Liu M, Li YX, Cao B, Sadovsky Y, Wang YL., 2021 Quantitative chemoproteomics reveals O-GlcNAcylation of Cystathionine γ-lyase (CSE) represses trophoblast syncytialization., Liu J#, Shao X#, Qin W#, Yanling Zhang#, Dang F, Yang Q, Yu X, Li YX, Chen X, Wang C, Wang YL., 2021 Single-cell immune landscape of human recurrent miscarriage., Wang F#, Jia W#, Fan M#, Shao X#. Li Z, Liu Y, Ma Y, Shao X, Li YX, Li R, Tu Q, Wang YL., 2021 miR-210 regulates placental adaptation to maternal hypoxic stress during pregnancy., Bian X, Liu J, Yang Q, Liu Y, Jia W, Zhang X, Li YX, Shao X, Wang YL., 2021 Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation., Ma Y#, Yang Q#, Fan M#, Zhang L, Gu Y, Jia W, Li Z, Wang F, Li YX, Wang J, Li R, Shao X, Wang YL., 2020 Uterine Scarring Leads to Adverse Pregnant Consequences by Impairing the Endometrium Response to Steroids., Li Z#, Bian X#, Ma Y, Yang Q, Jia W, Liu J, Wang F, Liu M, Li YX, Shao X, Wang YL., 2020 Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia., Shao X#, Wang Y#, Liu Y#, Guo X, Li D, Huo R, Jia W, Cao G, Li YX, Liu M, Sha J, Zhao Y, Wang YL., 2019 Placental defects are involved in most gene mutations that cause embryonic and fetal death., Shao X, Tan C, Chen D, Wang YL., 2018 Testosterone Represses Estrogen Signaling by Upregulating miR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia., Shao X#, Liu Y#, Liu M, Wang Y, Yan L, Wang H, Ma L, Li YX, Zhao Y, Wang YL., 2017 MicroRNA-210 contributes to preeclampsia by down-regulating KCMF1., Luo R#, Shao X#, Xu P, Liu Y, Wang Y, Zhao Y, Liu M, Ji L, Li YX, Chang C, Qiao J, Peng C, Wang YL., 2014

Areas of Focus

妊娠适应性调节
滋养层细胞代谢

Publications

Orchestrated feedback regulation between melatonin and sex hormones involving GPER1-PKA-CREB signaling in the placenta., Shao X#, Yang Y#, Liu Y#, Wang Y#, Zhao Y, Yu X, Liu J, Li YX, Wang YL*., 2023
The mystery of the life tree: the placenta., Shao X#, Yu W#, Yang Y#, Wang F, Yu X, Wu H, Ma Y, Cao B*, Wang YL*., 2022
Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at mid-gestation highlights the defective impacts on fetal health., Chen J#, Du L#, Wang F#, Shao X#, Wang X, Yu W, Bi S, Chen D, Pan X, Zeng S, Huang L, Liang Y, Li Y, Chen R, Xue F, Li X, Wang S, Zhuang M, Liu M, Lin L, Yan H, He F, Yu L, Jiang Q, Xiong Z, Zhang L, Cao B*, Wang YL*, Chen D*., 2022
Placental development and Pregnancy-Associated Diseases., Yu X#, Wu Hong#, Yang Y, Wang F, Wang YL*, Shao X*., 2022
Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia., Li G#, Wang Y#, Cao G#, Ma Y, Li YX, Zhao Y*, Shao X*, Wang YL*., 2022
Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply., Shao X#, Cao G#, Chen D#, Liu J, Yu B, Liu M, Li YX, Cao B*, Sadovsky Y*, Wang YL*., 2021
Quantitative chemoproteomics reveals O-GlcNAcylation of Cystathionine γ-lyase (CSE) represses trophoblast syncytialization., Liu J#, Shao X#, Qin W#, Yanling Zhang#, Dang F, Yang Q, Yu X, Li YX, Chen X, Wang C*, Wang YL*., 2021
Single-cell immune landscape of human recurrent miscarriage., Wang F#, Jia W#, Fan M#, Shao X#. Li Z, Liu Y, Ma Y, Shao X, Li YX, Li R*, Tu Q*, Wang YL*., 2021
miR-210 regulates placental adaptation to maternal hypoxic stress during pregnancy., Bian X, Liu J, Yang Q, Liu Y, Jia W, Zhang X, Li YX, Shao X*, Wang YL*., 2021
Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation., Ma Y#, Yang Q#, Fan M#, Zhang L, Gu Y, Jia W, Li Z, Wang F, Li YX, Wang J, Li R*, Shao X*, Wang YL*., 2020
Uterine Scarring Leads to Adverse Pregnant Consequences by Impairing the Endometrium Response to Steroids., Li Z#, Bian X#, Ma Y, Yang Q, Jia W, Liu J, Wang F, Liu M, Li YX, Shao X*, Wang YL*., 2020
Association of imbalanced sex hormone production with excessive procoagulation factor SerpinF2 in preeclampsia., Shao X#, Wang Y#, Liu Y#, Guo X, Li D, Huo R, Jia W, Cao G, Li YX, Liu M, Sha J, Zhao Y, Wang YL*., 2019
Placental defects are involved in most gene mutations that cause embryonic and fetal death., Shao X, Tan C, Chen D, Wang YL*., 2018
Testosterone Represses Estrogen Signaling by Upregulating miR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia., Shao X#, Liu Y#, Liu M, Wang Y, Yan L, Wang H, Ma L, Li YX, Zhao Y*, Wang YL*., 2017
MicroRNA-210 contributes to preeclampsia by down-regulating KCMF1., Luo R#, Shao X#, Xu P, Liu Y, Wang Y, Zhao Y, Liu M, Ji L, Li YX, Chang C, Qiao J, Peng C*, Wang YL*., 2014

妊娠适应性调节滋养层代谢胎盘内分泌机制子痫前期疾病

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Area of Focus
胚胎 | 发育 | 哺乳动物 | 培养 | 系统 | 优化 | 仿生材料 | 监测 | 小鼠 | 人类 | 胎盘 | 滋养层 | 合体化 | 子宫 | 植入 | 流产 | 先兆子痫 | Iugr | 病理 | 机制 | 卵泡 | 激活 | 卵巢 | Pof | Pcos | 干细胞 | 治疗 | 转录组学 | 代谢组学 | 生育力

李静宜 - 中国科学院

Area of Focus
衰老 | 疾病 | 多组学 | 机制 | 干预 | 靶标 | 基因组学 | 转录组学 | 蛋白质组学 | 生物信息学

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