Professor | 黄洪标 | 数字化转型顾问

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Name	黄洪标
Contact Information	huanghongbiao@gzhmu.edu.cn
Language ability	中文, 英语
Province	广东

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Name

黄洪标

Contact Information

huanghongbiao@gzhmu.edu.cn

Language ability

中文, 英语

Province

广东

University/Lab Affiliation and Title	广州医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	博士: 未提及广东省“特支计划”百千万工程青年拔尖人才广东省高校优秀青年教师培育对象广州市高层次人才
Awards	广东省“特支计划”百千万工程青年拔尖人才广东省高校优秀青年教师培养对象教育部高校优秀成果自然科学二等奖 (2021): 蛋白酶体功能调节在肿瘤中的作用及其意义中华医学会科技进步三等奖 (2017): 蛋白酶体功能调节及其意义广州市科技进步一等奖 (2016): 蛋白酶体功能调节及其意义

University/Lab Affiliation and Title

广州医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

博士: 未提及
广东省“特支计划”百千万工程青年拔尖人才
广东省高校优秀青年教师培育对象
广州市高层次人才

Awards

广东省“特支计划”百千万工程青年拔尖人才
广东省高校优秀青年教师培养对象
教育部高校优秀成果自然科学二等奖 (2021): 蛋白酶体功能调节在肿瘤中的作用及其意义
中华医学会科技进步三等奖 (2017): 蛋白酶体功能调节及其意义
广州市科技进步一等奖 (2016): 蛋白酶体功能调节及其意义

Areas of Focus	蛋白质修饰与肿瘤
Publications	HSP90β Impedes STUB1-Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma, Liao Y, Liu Y, Yu C, Lei Q, Cheng J, Kong W, Yu Y, Zhuang X, Sun W, Yin S, Cai G, Huang H, 2023 Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression, Xiaohong Xia, Tumei Hu, Xiaoyue He, Yuan Liu, Cuifu Yu, Weiyao Kong, Yuning Liao, Daolin Tang, Jinbao Liu, Hongbiao Huang, 2023 SNS-023 sensitizes hepatocellular carcinoma to sorafenib by inducing degradation of cancer drivers SIX1 and RPS16, Yuan Liu, Weiyao Kong, Cuifu Yu, Zhenlong Shao, Qiucheng Lei, Yuanfei Deng, Gengxi Cai, Xuefen Zhuang, Wenshuang Sun, Shigang Wu, Rong Wang, Xiang Chen, Guoxing Chen, Hongbiao Huang, Yuning Liao, 2023 A SIX1 degradation inducer blocks excessive proliferation of prostate cancer, Yuning Liao, Wenshuang Sun, Zhenlong Shao, Yuan Liu, Xiaoyu Zhong, Yuanfei Deng, Fang Liu, Hongbiao Huang, Jinbao Liu, 2022 A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance, Liao Y, Liu Y, Shao Z, Xia X, Deng Y, Cai J, Yao L, He J, Yu C, Hu T, Sun W, Liu F, Tang D, Liu J, Huang H, 2021 USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells, Liao Y, Shao Z, Liu Y, Xia X, Deng Y, Yu C, Sun W, Kong W, He X, Liu F, Guo Z, Chen G, Tang D, Gan H, Liu J, Huang H, 2021 Selective degradation of AR-V7 to overcome castration resistance of prostate cancer, Liao Y, Yu C, Shao Z, Xia X, Hu T, Kong W, He X, Sun W, Deng Y, Liao Y, Huang H, 2021 The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression, Xia X, Huang C, Liao Y, Liu Y, He J, Shao Z, Hu T, Yu C, Jiang L, Liu J, Huang H, 2021 Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy, Liao Y, Liu Y, Xia X, Shao Z, Huang C, He J, Jiang L, Tang D, Liu J, Huang H, 2020 Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis, Xia X, Liao Y, Huang C, Liu Y, He J, Shao Z, Jiang L, Dou QP, Liu J, Huang H, 2019 Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide, Xia X, Huang C, Liao Y, Liu Y, He J, Guo Z, Jiang L, Wang X, Liu J, Huang H, 2019 Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer, Liao Y, Guo Z, Xia X, Liu Y, Huang C, Jiang L, Wang X, Liu J, Huang H, 2019 USP10 Modulates the SKP2/Bcr-Abl axis via Stabilizing SKP2 in Chronic Myeloid Leukemia, Liao Y, Liu N, Xia X, Guo Z, Li Y, Jiang L, Zhou R, Tang D, Huang H, Liu J, 2019 Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination, Liao Y, Xia X, Liu N, Cai J, Guo Z, Li Y, Jiang L, Dou Q, Tang D, Huang H, Liu J, 2018 Targeting proteasome associated deubiquitinases as a novel strategy for the treatment of estrogen receptor positive breast cancer, Xia X, Liao Y, Guo Z, Li Y, Jiang L, Zhang F, Huang C, Liu Y, Wang X, Liu N, Liu J, Huang H, 2018

Areas of Focus

蛋白质修饰与肿瘤

Publications

HSP90β Impedes STUB1-Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma, Liao Y, Liu Y, Yu C, Lei Q, Cheng J, Kong W, Yu Y, Zhuang X, Sun W, Yin S, Cai G, Huang H, 2023
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression, Xiaohong Xia, Tumei Hu, Xiaoyue He, Yuan Liu, Cuifu Yu, Weiyao Kong, Yuning Liao, Daolin Tang, Jinbao Liu, Hongbiao Huang, 2023
SNS-023 sensitizes hepatocellular carcinoma to sorafenib by inducing degradation of cancer drivers SIX1 and RPS16, Yuan Liu, Weiyao Kong, Cuifu Yu, Zhenlong Shao, Qiucheng Lei, Yuanfei Deng, Gengxi Cai, Xuefen Zhuang, Wenshuang Sun, Shigang Wu, Rong Wang, Xiang Chen, Guoxing Chen, Hongbiao Huang, Yuning Liao, 2023
A SIX1 degradation inducer blocks excessive proliferation of prostate cancer, Yuning Liao, Wenshuang Sun, Zhenlong Shao, Yuan Liu, Xiaoyu Zhong, Yuanfei Deng, Fang Liu, Hongbiao Huang, Jinbao Liu, 2022
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance, Liao Y, Liu Y, Shao Z, Xia X, Deng Y, Cai J, Yao L, He J, Yu C, Hu T, Sun W, Liu F, Tang D, Liu J, Huang H, 2021
USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells, Liao Y, Shao Z, Liu Y, Xia X, Deng Y, Yu C, Sun W, Kong W, He X, Liu F, Guo Z, Chen G, Tang D, Gan H, Liu J, Huang H, 2021
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer, Liao Y, Yu C, Shao Z, Xia X, Hu T, Kong W, He X, Sun W, Deng Y, Liao Y, Huang H, 2021
The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression, Xia X, Huang C, Liao Y, Liu Y, He J, Shao Z, Hu T, Yu C, Jiang L, Liu J, Huang H, 2021
Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy, Liao Y, Liu Y, Xia X, Shao Z, Huang C, He J, Jiang L, Tang D, Liu J, Huang H, 2020
Deubiquitination and stabilization of estrogen receptor α by ubiquitin-specific protease 7 promotes breast tumorigenesis, Xia X, Liao Y, Huang C, Liu Y, He J, Shao Z, Jiang L, Dou QP, Liu J, Huang H, 2019
Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide, Xia X, Huang C, Liao Y, Liu Y, He J, Guo Z, Jiang L, Wang X, Liu J, Huang H, 2019
Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer, Liao Y, Guo Z, Xia X, Liu Y, Huang C, Jiang L, Wang X, Liu J, Huang H, 2019
USP10 Modulates the SKP2/Bcr-Abl axis via Stabilizing SKP2 in Chronic Myeloid Leukemia, Liao Y, Liu N, Xia X, Guo Z, Li Y, Jiang L, Zhou R, Tang D, Huang H, Liu J, 2019
Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination, Liao Y, Xia X, Liu N, Cai J, Guo Z, Li Y, Jiang L, Dou Q, Tang D, Huang H, Liu J, 2018
Targeting proteasome associated deubiquitinases as a novel strategy for the treatment of estrogen receptor positive breast cancer, Xia X, Liao Y, Guo Z, Li Y, Jiang L, Zhang F, Huang C, Liu Y, Wang X, Liu N, Liu J, Huang H, 2018

蛋白质修饰肿瘤翻译后修饰癌症机制蛋白酶体泛素化去泛素化癌症抵抗蛋白质降解肿瘤学

魏潇凡 - 北京大学

Area of Focus
肿瘤 | 侵袭 | 转移 | 分子生物学 | 细胞微环境 | 整合素 | 信号 | 蛋白质修饰 | 泛素化 | 去泛素化

廖宇宁 - 广州医科大学

Area of Focus
翻译后修饰 | 癌症 | Usp1 | Uaf1 | Rps16 | 泛素化 | 降解 | 肝癌 | 恶性进展 | 蛋白质稳定性

翁良 - 北京大学

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