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潘星华
panvictor@smu.edu.cn
英语, 中文
广东
南方医科大学
Basic Medical Sciences
  • 医学学士和硕士学位:广州南方医科大学
  • 遗传学博士学位:上海复旦大学
  • 分子肿瘤学博士后培训:北京协和医学院暨中国医学科学院
  • 基因组学博士后培训:美国耶鲁大学
  • 发表论文110多篇,包括《自然》和《细胞》
  • 编写中英文专著6部
  • 持有中美发明专利14项
  • 现任 - 南方医科大学 - 生化与分子生物学教研室主任
  • 曾任 - 耶鲁大学 - 遗传系研究员和项目PI
  • CastUSA单细胞基因组学先锋奖
  • 国际科学组织Vebleo会士
  • 中国侨联特聘专家
单细胞组学技术创新
肿瘤异质性与生物标记
基因组医学
单细胞生物信息学
干细胞与再生医学
  • Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution., Liyao Mai, Zebin Wen, Yulong Zhang, Yu Gao, Guanchuan Lin, Zhiwei Lian, Xiang Yang, Jingjing Zhou, Xianwei Lin, Chaochao Luo, Wanwan Peng, Caiming Chen, Jiajia Peng, Duolian Liu, Sadie L Marjani, Qian Tao, Yongping Cui, Junxiao Zhang, Xuedong Wu, Sherman M Weissman, Xinghua Pan., 2023
  • A CCL2+DPP4+ subset of mesenchymal stem cells expedites aberrant formation of creeping fat in humans., Lan Bai, Fengfei Wu, Fangting Wu, Qian Zhou, Xi Liu, Jieying Fei, Da Zhang, Weidong Wang, Yi Tao, Yubing Lin, Qiaoqiao Lin, Xinghua Pan, Kai Sun, Fang Xie., 2023
  • CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy., Xue Bai, Ze-Qin Guo, Yan-Pei Zhang, Zhen-zhen Fan, Li-Juan Liu, Li Liu, Li-Li Long, Si-Cong Ma, Jian Wang, Yuan Fang, Xin-Ran Tang, Yu-Jie Zeng, Xinghua Pan, De-Hua Wu, Zhong-Yi Dong., 2023
  • PARP inhibition induces synthetic lethality and adaptive immunity in LKB1-mutant lung cancer., Li-Li Long, Si-Cong Ma, Ze-Qin Guo, Yan-Pei Zhang, Zhenzhen Fan, Li-Juan Liu, Li Liu, Duan-Duan Han, Meng-Xin Leng, Jian Wang, Xue-Jun Guo, Jia-Le Tan, Xiao-Ting Cai, Yan Lin, Xinghua Pan, De-Hua Wu, Xue Bai, Zhong-Yi Dong., 2023
  • Discovery of 194 Unreported Conopeptides and Identification of a New Protein Disulfide Isomerase in Conus caracteristicus Using Integrated Transcriptomic and Proteomic Analysis., Han Zhang, Lei Wang, Yinbin Qiu, Fahui Gong, Baoting Nong, Xinghua Pan., 2022
  • Preparation and Functional Identification of a Novel Conotoxin QcMNCL-XIII0.1 from Conus quercinus., Han Zhang, Anwen Liang, Xinghua Pan., 2022
  • Sample‑multiplexing approaches for single‑cell sequencing., Zhang Y, Xu S, Wen Z, Gao JY, Li S, Weissman SM, Pan X., 2022
  • Tumorigenicity risk of iPSCs in vivo: nip it in the bud., Chaoliang Zhong, Miao Liu, Xinghua Pan, Haiying Zhu., 2022
  • Identification of Novel Conopeptides and Distinct Gene Superfamilies in the Marine Cone Snail Conus quercinus., Han Zhang, Lei Wang, Xiang Yang, Zhiwei Lian, Yinbin Qiu, Zhanying Dong, Xuedong Wu, Xinghua Pan., 2021
  • The role of serum amyloid A1 in the adipogenic differentiation of human adipose-derived stem cells basing on single-cell RNA sequencing analysis., Rongmei Qu, Kai He, Yuchao Yang, Tingyu Fan, Bing Sun, Asmat Ullah Khan, Wenhua Huang, Jun Ouyang, Xinghua Pan, Jingxing Dai., 2022
  • Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture., Yanfang Lu, Miao Liu, Jennifer Yang, Sherman Weissman, Xinghua Pan, Samuel Katz, Siyuan Wang., 2021
  • MustSeq, an alternative approach for multiplexible strand-specific 3' end sequencing of mRNA transcriptome confers high efficiency and practicality., Liyao Mai, Yinbin Qiu, Zhiwei Lian, Caiming Chen, Linlin Wang, Yao Yin, Siqi Wang, Xiang Yang, Yazi Li, Wanwan Peng, Chaochao Luo, Xinghua Pan., 2021
  • Mitogenome and comprehensive phylogenetic analyses support rapid diversifications among species groups of small-eared shrews, genus Cryptotis (Mammalia: Eulipotyphla: Soricidae)., Kai He, Xing Chen, Yin-Bin Qiu, Zhu Liu, Wen-Zhi Wang, Neal Woodman, Jesús E. Maldonado, Xinghua Pan., 2021
  • Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells., Chaochao Luo, Wanwan Peng, Jia Kang, Caiming Chen, Jiajia Peng, Yue Wang, Qian Tang, Hailong Xie, Yazi Li, Xinghua Pan., 2021
  • Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres., Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, Li J, Marjani SL, Costa J, Weissman SM, Qi F, Pan X, Liu L., 2021
  • Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma., Zhou Y, Yang D, Yang Q, Lv X, Huang W, Zhou Z, Wang Y, Zhang Z, Yuan T, Ding X, Tang L, Zhang J, Yin J, Huang Y, Yu W, Wang Y, Zhou C, Su Y, He A, Sun Y, Shen Z, Qian B, Meng W, Fei J, Yao Y, Pan X, Chen P, Hu H., 2020
  • Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing., Ma X, Guo J, Liu K, Chen L, Liu D, Dong S, Xia J, Long Q, Yue Y, Zhao P, Hu F, Xiao Z, Pan X, Xiao K, Cheng Z, Ke Z, Chen ZS, Zou C., 2020
  • Expanded encyclopaedias of DNA elements in the human and mouse genomes., The ENCODE Project Consortium, Jill E Moore, Michael J Purcaro, Henry E Pratt, et al., 2020
  • Perspectives on ENCODE., The ENCODE Project Consortium, Michael P Snyder, Thomas R Gingeras, et al., 2020
  • Putative Regulators for the Continuum of Erythroid Differentiation Revealed by Single-cell Transcriptomes of Human Bone Marrow and Umbilical Cord Blood., Huang H, Zhao Y, Zhong J, Zhang X, Liu Q, Qiu X, Chen S, Yang H, Hillyer C, Mohandas N, Pan X, Xu X., 2020
  • Identification and Single-Cell Analysis of Viable Circulating Tumor Cells by a Mitochondrion-Specific AIE Bioprobe., Situ B, Ye X, Zhao Q, Mai L, Huang Y, Wang S, Chen J, Li B, He B, Zhang Y, Zou J, Tang BJ, Pan X, Zheng L., 2020
  • An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo., Cen B, Wei Y, Huang W, Teng M, He S, Li J, Wang W, He G, Bai X, Liu X, Yuan Y, Pan X, Ji A., 2018
  • Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway., Cen B, Liao W, Wang Z, Gao L, Wei Y, Huang W, He S, Wang W, Liu X, Pan X, Ji A., 2018
  • Characterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatment., Zhang J, Späth SS, Marjani SL, Zhang W, Pan X., 2018
  • Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells., Han L, Wu HJ, Zhu H, Kim KY, Marjani SL, Riester M, Euskirchen G, Zi X, Yang J, Han J, Snyder M, Park IH, Irizarry R, Weissman SM, Michor F, Fan R, Pan X., 2017
  • Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors., Yang J, Tanaka Y, Seay M, Li Z, Jin J, Garmire LX, Zhu X, Taylor A, Li W, Euskirchen G, Halene S, Kluger Y, Snyder MP, Park IH, Pan X, Weissman SM., 2017
  • Evolution and heterogeneity of non-hereditary colorectal cancer revealed by single-cell exome sequencing., Wu H, Zhang XY, Hu Z, Hou Q, Zhang H, Li Y, Li S, Yue J, Jiang Z, Weissman SW, Pan X, Ju BG, Wu S., 2017
  • Next-generation molecular diagnosis: single-cell sequencing from bench to bedside., Zhu W, Zhang XY, Marjani SL, Zhang J, Zhang W, Wu S, Pan X., 2017
  • Single-Cell Sequencing for Precise Cancer Research: Progress and Prospects., Zhang X, Marjani SL, Hu Z, Weissman SM, Pan X, Wu S., 2016
  • A Molecular Chipper Technology for CRISPR sgRNA Library Generation and Functional Mapping of Noncoding Regions., Cheng J, Roden C, Pan W, Zhu S, Baccei A, Pan X, Jiang T, Kluger Y, Weissman S, Guo S, Flavell R, Ding Y, Lu J., 2016
  • Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family., Hysolli E, Tanaka Y, Su J, Kim KY, Zhong T, Janknecht R, Zhou XL, Geng L, Qiu C, Pan X, Jung YW, Cheng J, Lu J, Zhong M, Weissman SM, Park IH., 2016
  • Th17 cells transdifferentiation into regulatory T cells during resolution of inflammation., Gagliani N, Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA., 2015
  • Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming., Tanaka Y, Hysolli E, Su J, Xiang Y, Kim KY, Zhong M, Li Y, Heydari K, Euskirchen G, Snyder MP, Pan X, Weissman SM, Park IH., 2015
  • X chromosome of female cells shows dynamic changes in status during human somatic cell reprogramming., Kim KY, Hysolli E, Tanaka Y, Wang B, Jung YW, Pan X, Weissman SM, Park IH., 2014
  • Single-cell analysis of the transcriptome and its application in the characterization of stem cells and early embryos., Liu N, Liu L, Pan X., 2014
  • Non-stochastic reprogramming from a privileged somatic cell state., Guo S, Zi X, Schultz V, Cheng J, Zhong M, Koochaki S, Megyola CM, Pan X, Heydari K, Weissman SM, Gallagher PG, Krause DS, Fan R, Lu J., 2014
  • Co-detection and sequencing of genes and transcripts from the same single cells enabled by a microfluidics platform., Han L, Zi X, Garmire LX, Wu Y, Weissman SM, Pan X, Fan R., 2014
  • Single Cell Analysis: From Technology to Biology and Medicine., Xinghua Pan., 2014
  • Robust measurement of telomere length in single cells., Wang F, Pan X, Kalmbach K, Seth-Smith ML, Ye X, Antumes DM, Yin Y, Liu L, Keefe DL, Weissman SM., 2013
  • Transcriptome regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2)., Tanaka Y, Kim KY, Zhong M, Pan X, Weissman SM, Park I-H., 2014
  • Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing., Dan J, Liu Y, Liu N, Chiourea M, Okuka M, Wu T, Ye X, Mou C, Wang L, Wang L, Yin Y, Yuan J, Zuo B, Wang F, Li Z, Pan X, Yin Z, Chen L, Keefe DL, Gagos S, Xiao A, Liu L., 2014
  • Two methods for full-length RNA sequencing for low quantities of cells and single cells., Pan X, Durrett RE, Zhu H, Tanaka Y, Li Y, Zi X, Marjani SL, Euskirchen G, Ma C, Lamotte RH, Park IH, Snyder MP, Mason CE, Weissman SM., 2013
  • Functional genomic screen of human stem cell differentiation reveals pathways involved in neurodevelopment and neurodegeneration., Zhang Y, Schulz V, Reed B, Wang Z, Pan X, Mariani J, Euskirchenc G, Snyder M, Vaccarino FM, Ivanova N, Weissman SM, Szekely AM., 2013
  • Cuprous oxide nanoparticles inhibit the growth and metastasis of melanoma by targeting mitochondria., Wang Y, Yang F, Zhang HX, Zi XY, Pan XH, Chen F, Luo WD, Li JX, Zhu HY, Hu YP., 2013
  • Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells (iPSCs)., Wang F, Yin Y, Ye Xiaoying, Liu K, Zhu H, Wang L, Chiourea M, Okuka M, Jia G, Dan, J, Zuo B, Li M, Zhang Q, Liu N, Chen L, Pan X, Gagos S, Keefee D, Lin L., 2012
  • Germline competency of parthenogenetic embryonic stem cells from immature oocytes of adult mouse ovary., Liu Z, Hu Z, Pan X, Li M, Togun TA, Tuck D, Pelizzola M, Huang J, Ye X, Yin Y, Liu M, Li C, Chen Z, Wang F, Zhou L, Chen L, Keefe DL, Liu L., 2011
  • X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils., Yasukochia Y, Maruyamab O, Mahajana MC, Paddenc C, Euskirchend GM, Schulze V, Hirakawaf H, Kuharag S, Pan XH, Newburgerc PE, Snyder M, Weissmana SM., 2010
  • A procedure for highly specific, hypersensitive and unbiased whole genome amplification., Pan X, Urban AE, Dean P, Vincent S, Grubbert F, Hu Y, Snyder M, Weissman SM., 2008
  • Murine fertilized ovum, blastomere and morula cells lacking SP phenotype., Xu Y, He Z, Zhu H, Chen X, Li J, Zhang H, Pan X, Hu Y., 2007
  • An approach for global scanning of single nucleotide variations., Pan X, Weissman SM., 2002
  • Molecular evolution of MHC-DQA genes: I. The maintenance of interallelic divergence and the influence of GC content on gene structure., Pan X, Fu J., 1997
  • Molecular evolution of MHC-DQA genes: II. Phylogenetic analysis based on nucleotide substitution and synonymous codon usage bias., Pan X, Fu J., 1997
  • Research on the genetic susceptibility for Myasthenia Gravis in Chinese Hans by genotyping of HLA-DQA1 with PCR-RFLP., Pan X, Lu J, Inoko H, Tan CC, Geng Z, Zhang R, Tu L, Jiang J., 1995
  • Cytogenetics studies of two Calyptrate Dipteras (Sarcophagidae and Calliphoridae: Diptera)., Pan X, He L., 1991
单细胞 技术 创新 肿瘤 异质性 生物标记 基因组 医学 生物信息学 干细胞

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