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庄红芹
hqzhuang@nju.edu.cn
中文, 英语
江苏
南京大学
Life Sciences
  • 2017年: 江苏省科学技术一等奖
  • 2020年: 中国发明协会发明创业奖(成果奖)一等奖
  • 2017年: 江苏医药科技进步奖二等奖
经典凋亡蛋白FADD的非凋亡功能研究
脂代谢、能量代谢与肥胖干预
肿瘤基因治疗
  • Combined Cellular Thermometry Reveals That Salmonella typhimurium Warms Macrophages by Inducing a Pyroptosis-like Phenotype, Wu L, Chen F, Chang X, Li L, Yin X, Li C, Wang F, Li C, Xu Q, Zhuang H, Gu N, Hua ZC, 2022
  • Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase, Lin Y, Peng N, Li J, Zhuang H, Hua ZC, 2013
  • FADD is a key regulator of lipid metabolism, Zhuang H, Wang X, Zha D, Gan Z, Cai F, Du P, Yang Y, Yang B, Zhang X, Yao C, Zhou Y, Jiang C, Guan S, Zhang X, Zhang J, Jiang W, Hu Q, Hua ZC, 2016
  • Extracellular signal regulated kinase 5 promotes cell migration, invasion and lung metastasis in a FAK-dependent manner, Jiang W, Cai F, Xu H, Lu Y, Chen J, Liu J, Cao N, Zhang X, Chen X, Huang Qilai, Zhuang H, Hua ZC, 2020
  • Extracellular signal-regulated kinase 5 increases radioresistance of lung cancer cells by enhancing the DNA damage response, Jiang W, Jin G, Cai F, Chen X, Cao N, Zhang X, Liu J, Chen F, Wang F, Dong W, Zhuang H, Hua ZC, 2019
  • Sulfide:quinone oxidoreductase alleviates ferroptosis in acute kidney injury via ameliorating mitochondrial dysfunction of renal tubular epithelial cells, Cai F, Li D, Xie Y, Wang X, Ma H, Xu H, Cheng J, Zhuang H, Hua ZC, 2023
  • Tannic acid assisted anti-TNF-α nanobody assembly modulating the epithelial barrier dysregulation of allergic rhinitis, Fu S, Cao Z, Huang B, Yin T, Huang C, Bi Z, Yao Y, Chang X, Zhuang H, Hua ZC, 2023
  • ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis, Bi Z, Chen J, Chang X, Li D, Yao Y, Cai F, Xu H, Cheng J, Hua ZC, Zhuang H, 2023
  • ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD, Cai F, Xu H, Cao N, Zhang X, Liu J, Lu Y, Chen J, Yang Y, Cheng J, Hua ZC, Zhuang H, 2020
  • Hydrogel-metal-organic-framework hybrids mediated efficient oral delivery of siRNA for the treatment of ulcerative colitis, Gao M, Yang C, Wu C, Chen Y, Zhuang H, Wang J, Cao Z, 2022
  • Characterization and Analysis of the Temporal and Spatial Dynamic of Several Enteritis Modeling Methodologies, Xu H, Cai F, Li P, Wang X, Yao Y, Chang X, Bi Z, Sun H, Zhuang H, Hua ZC, 2021
  • Emerging roles of hnRNP A2B1 in cancer and inflammation, Xu H, Li P, Wang X, Zhuang H, Hua ZC, 2022
  • ADT-OH inhibits malignant melanoma metastasis in mice via suppressing CSE/CBS and FAK/Paxillin signaling pathway, Cai FF, Xu HR, Yu SH, Li P, Lu YY, Chen J, Bi ZQ, Sun HS, Cheng J, Zhuang HQ, Hua ZC, 2022
  • Role of FADD Phosphorylation in Regulating Glucose Homeostasis: from Proteomic Discovery to Physiological Validation, Yao C, Zhuang H, Du P, Cheng W, Yang B, Guan S, Hu Y, Zhu D, Christine M, Shi L, Hua ZC, 2013
  • Proteomic screening of anaerobically regulated promoters from Salmonella and its antitumor applications, Chen J, Wei D, Zhuang H, Qiao Y, Tang B, Zhang X, Wei J, Fang S, Chen G, Du P, Huang X, Jiang W, Hu Q, Hua ZC, 2011
  • FADD phosphorylation impaired islet morphology and function, Yao C, Zhuang H, Cheng W, Lin Y, Du P, Yang B, Huang X, Chen S, Hu Q, Hua ZC, 2015
  • Recombinant Bifidobacterium longum Carrying Endostatin Protein Alleviates Dextran Sodium Sulfate-Induced Colitis and Colon Cancer in Rats, Bi Z, Cui E, Yao Y, Chang X, Wang X, Zhang Y, Xu GX, Zhuang H, Hua ZC, 2022
  • Down-regulation of HSP27 sensitizes TRAIL-resistant tumor cell to TRAIL-induced apoptosis, Zhuang H, Jiang W, Cheng W, Qian K, Dong W, Cao L, Huang Q, Li S, Dou F, Chiu JF, Fang XX, Lu M, Hua ZC, 2010
  • Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells, Cao N, Lu Y, Liu J, Cai F, Xu H, Chen J, Zhang X, Hua ZC, Zhuang H, 2020
  • AK2 Promotes the Migration and Invasion of Lung Adenocarcinoma by Activating TGF-β/Smad Pathway In vitro and In vivo, Cai F, Xu H, Zha D, Wang X, Li P, Yu S, Yao Y, Chang X, Chen J, Lu Y, Hua ZC, Zhuang H, 2021
  • Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions, Zhuang H, Jiang W, Zhang X, Qiu F, Gan Z, Cheng W, Zhang J, Guan S, Tang B, Huang Q, Wu X, Huang X, Jiang W, Hu Q, Lu M, Hua ZC, 2013
  • Aspirin potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer by targeting GRP78 activity, Zhang X, Chen J, Cheng C, Li P, Cai F, Xu H, Lu Y, Cao N, Liu J, Wang J, Hua ZC, Zhuang H, 2020
  • Comparative proteomics analysis reveals roles for FADD in the regulation of energy metabolism and proteolysis pathway in mouse embryonic fibroblast, Zhuang H, Gan Z, Jiang W, Zhang X, Hua ZC, 2013
  • FADD phosphorylation contributes to development of renal fibrosis by accelerating epithelial-mesenchymal transition, Lin Y, Cai F, Wang X, Yang Y, Ren Y, Yao C, Yin X, Zhuang H, Hua Z, 2022
  • Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner, Chen M, Wang X, Zha D, Cai F, Zhang W, He Y, Huang Q, Zhuang H, Hua ZC, 2016
  • Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor, Lin Y, Peng N, Zhuang H, Zhang D, Wang Y, Hua ZC, 2014
  • FADD phosphorylation modulates blood glucose levels by decreasing the expression of insulin-degrading enzyme, Lin Y, Liu J, Chen J, Yao C, Yang Y, Wang J, Zhuang H, Hua ZC, 2020
  • Functional specific roles of FADD: comparative proteomic analyses from knockout cell lines, Zhuang H, Gan Z, Jiang W, Zhang X, Hua ZC, 2013
  • Expression, Purification and Biological Characterization of The Amino-Terminal Fragment of Urokinase in Pichia pastoris, Li J, Lin Y, Zhuang H, Hua ZC, 2013
  • Herbal compound triptolide synergistically enhanced antitumor activity of vasostatin120-180, Lin Y, Yang X, Lu M, Zheng W, Zhang J, Zhuang H, Hua ZC, 2013
  • Expression, purification and biological characterization of human vasostatin120–180 in Pichia pastoris, Lin Y, Yang X, Lu M, Zhuang H, Hua ZC, 2013
Fadd 凋亡 非凋亡 脂代谢 能量代谢 肥胖 基因治疗 肿瘤 癌症 干预

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