姚帆
fyao@mail.hzau.edu.cn
中文, 英语
湖北
华中农业大学
Life Sciences
  • 2006-2012: 生物化学与分子生物学博士, 中科院上海生命科学研究院
  • 2002-2006: 生命科学与技术学士, 武汉大学
  • 2020-至今: 教授, 华中农业大学生物医学与健康学院
  • 2019-2020: 讲师, 美国得州大学MD安德森癌症中心
  • 2014-2019: 博士后, 美国得州大学MD安德森癌症中心
  • 2012-2013: 助理研究员, 中科院上海生命科学研究院营养科学研究所
肿瘤发生发展分子机制,肿瘤治疗耐受分子机制
  • A targetable LIFR- NF-κB -LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis., Yao F*#, Deng Y*, Zhao Y, Mei Y, Zhang Y, Liu X, Martinez C, Su X, Rosato R, Teng H, Hang Q, Yap S, Chen D, Wang Y, Chen M, Zhang M, Liang H, Xie D, Chen X, Zhu H, Chang J, You J, Sun Y, Gan B, Ma L#., 2021
  • Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance., Deng Y, Xia X, Zhao Y, Zhao Z, Martinez C, Yin W, Yao J, Hang Q, Wu W, Zhang J, Yu Y, Xia W, Yao F, Zhao D, Sun Y, Ying H, Hung M, Ma L., 2021
  • Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance., Hang Q, Zeng L, Wang L, Nie L, Yao F, Teng H, Deng Y, Yap S, Sun Y, Frank SJ, Chen J, Ma L., 2021
  • Proteome-wide Analysis Reveals Substrates of E3 Ligase RNF146 Targeted for Degradation., Nie L, Wang C, Li N, Feng X, Lee N, Su D, Tang M, Yao F, Chen J., 2020
  • Challenges and Strategies in Ascribing Functions to Long Noncoding RNAs., Zhao Y, Teng H, Yao F, Yap S, Sun Y, Ma L., 2020
  • piRNA-unbound PIWIL1 promotes metastasis., Yao F, Ma L., 2020
  • Long noncoding RNA MALAT1 suppresses breast cancer metastasis., Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, Liang H, Hung MC, You MJ, Sun Y, Ma L., 2018
  • SKP2 and OTUD1 govern non-proteolytic ubiquitination of YAP that promotes YAP nuclear localization and activity., Yao F, Xiao Z, Sun Y, Ma L., 2018
  • SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity., Yao F, Zhou Z, Kim J, Hang Q, Xiao Z, Ton BN, Chang L, Liu N, Zeng L, Wang W, Wang Y, Zhang P, Hu X, Su X, Liang H, Sun Y, Ma L., 2018
  • ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer., Zhang P, Xiao Z, Wang S, Zhang M, Wei Y, Hang Q, Kim J, Yao F, Rodriguez-Aguayo C, Ton BN, Lee M, Wang Y, Zhou Z, Zeng L, Hu X, Lawhon SE, Siverly AN, Su X, Li J, Xie X, Cheng X, Liu LC, Chang HW, Chiang SF, Lopez-Berestein G, Sood AK, Chen J, You MJ, Sun SC, Liang H, Huang Y, Yang X, Sun D, Sun Y, Hung MC, Ma L., 2018
  • Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types., Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H; Cancer Genome Atlas Research Network, Piwnica-Worms H, Ma L, Liang H., 2018
  • MicroRNAs and metastasis: small RNAs play big roles., Kim J, Yao F, Xiao Z, Sun Y, Ma L., 2018
  • USP51 promotes deubiquitination and stabilization of ZEB1., Zhou Z, Zhang P, Hu X, Kim J, Yao F, Xiao Z, Zeng L, Chang L, Sun Y, Ma L., 2017
  • Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis., Bao WD, Yao F, Deng YZ, Long LY, Wang JJ, Guan DX, Qian ZY, An P, Feng YY, He ZY, Wang XF, Phillip Koeffler H, Hu R, Wang J, Wang X, Wang F, Li JJ, Xie D., 2016
  • Recruitment of the phosphatase PP2A by RACK1 adaptor protein deactivates the transcription factor IRF3 and limits type I interferon signaling., Long L, Deng Y, Yao F, Guan D, Feng Y, Jiang H, Li X, Hu P, Lu X, Wang H, Li J, Gao X, Xie D., 2014
  • RACK1 modulates NF-kappaB activation by interfering with the interaction between TRAF2 and the IKK complex., Yao F, Long LY, Deng YZ, Feng YY, Ying GY, Bao WD, Li G, Guan DX, Zhu YQ, Li JJ and Xie D., 2014
  • RACK1 suppresses gastric tumorigenesis by stabilizing the beta-catenin destruction complex., Deng YZ, Yao F, Li JJ, Mao ZF, Hu PT, Long LY, Li G, Ji XD, Shi S, Guan DX, et al., 2012
  • Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model., Feng YX, Wang T, Deng YZ, Yang P, Li JJ, Guan DX, Yao F, Zhu YQ, Qin Y, Wang H, et al., 2011
肿瘤发生 分子机制 治疗耐受 肺癌 肝癌 Crispr-Cas9 遗传小鼠模型 Pdx模型 靶点鉴定 抑制剂评估

联系我们

欢迎与我们交流!
* Required
* Required
* Required
* Invalid email address
提交此表单,即表示您同意 IoT ONE 可以与您联系并分享洞察和营销信息。
不,谢谢,我不想收到来自 IoT ONE 的任何营销电子邮件。
提交

感谢您的信息!
我们会很快与你取得联系。