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魏瑗
weiy58@mail.sysu.edu.cn
中文, 英文
广东
中山大学
Life Sciences
  • 2013-2018 细胞生物学博士: 中山大学
  • 2009-2013 生物技术学士: 中山大学
  • 成就: 以B细胞塑造组织微环境及对肿瘤治疗影响为研究课题,发表在知名期刊上。
  • 2021至今 - 中山大学生命科学学院 - 副教授
  • 2018-2021 - 中山大学生命科学学院 - 博士后研究员
肿瘤免疫
B淋巴细胞
炎性组织微环境
  • miRNome targeting NF-κB signaling orchestrates macrophage-triggered cancer metastasis and recurrence., Chen DP, Wang JC, Liu ZY, Li PL, Chan KW, Wu XN, Yao WD, Yao T, Kuang DM, Wei Y., 2024
  • Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma., Wu RQ, Lao XM, Chen DP, Qin H, Mu M, Cao WJ, Deng J, Wan CC, Zhan WY, Wang JC, Xu L, Chen MS, Gao Q, Zheng L, Wei Y, Kuang DM., 2023
  • The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment., Lv J, Wei Y, Yin JH, Chen YP, Zhou GQ, Wei C, Liang XY, Zhang Y, Zhang CJ, He SW, He QM, Huang ZL, Guan JL, Shen JY, Li XM, Li JY, Li WF, Tang LL, Mao YP, Guo R, Sun R, Zheng YH, Zhou WW, Xiong KX, Wang SQ, Jin X, Liu N, Li GB, Kuang DM, Sun Y, Ma J., 2023
  • Targeting inflammatory macrophages rebuilds therapeutic efficacy of DOT1L inhibition in hepatocellular carcinoma., Yang YB, Wu CY, Wang XY, Deng J, Cao WJ, Tang YZ, Wan CC, Chen ZT, Zhan WY, Shan H, Kuang DM, Wei Y., 2023
  • PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma., Wang JC, Chen DP, Lu SX, Chen JB, Wei Y, Liu XC, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM, Chen MS, Zhou ZG., 2022
  • c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses., Wang XY, Wei Y, Hu B, Liao Y, Wang X, Wan WH, Huang CX, Mahabati M, Liu ZY, Qu JR, Chen XD, Chen DP, Kuang DM, Wang XH, Chen Y., 2022
  • Influence of gut and intratumoral microbiota on the immune microenvironment and anti-cancer therapy., Chen Y, Liu B, Wei Y, Kuang DM., 2021
  • B cell heterogeneity, plasticity, and functional diversity in cancer microenvironments., Wei Y, Huang CX, Xiao X, Chen DP, Shan H, He H, Kuang DM., 2021
  • PD-L1 Shapes B Cells as Safeguards in Circadian Clock Disorder., Wei Y, Wu CY, Kuang DM., 2021
  • Immune landscape and therapeutic strategies: new insights into PD-L1 in tumors., Wei Y, Xiao X, Lao XM, Zheng L, Kuang DM., 2021
  • B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis., Zeng QH, Wei Y, Lao XM, Chen DP, Huang CX, Lin QY, He M, Liao Y, Zheng L, Li B, Zhang GB, Chen Y, Kuang DM., 2020
  • The local immune landscape determines tumor PD-L1 heterogeneity and sensitivity to therapy., Wei Y, Zhao Q, Gao Z, Lao XM, Lin WM, Chen DP, Mu M, Huang CX, Liu ZY, Li B, Zheng L, Kuang DM., 2019
  • Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice., Wei Y, Lao XM, Xiao X, Wang XY, Wu ZJ, Zeng QH, Wu CY, Wu RQ, Chen ZX, Zheng L, Li B, Kuang DM., 2019
  • Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma., Chen DP, Ning WR, Li XF, Wei Y, Lao XM, Wang JC, Wu Y, Zheng L., 2018
  • Triptolide inhibits donor-specific antibody production and attenuates mixed antibody-mediated renal allograft injury., Zhao D, Li S, Liao T, Wei Y, Liu M, Han F, Luo Z, Liu X, Sun Q., 2018
  • Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma., Ouyang FZ, Wu RQ, Wei Y, Liu RX, Yang D, Xiao X, Zheng L, Li B, Lao XM, Kuang DM., 2016
  • Polarization of Tissue-Resident TFH-Like Cells in Human Hepatoma Bridges Innate Monocyte Inflammation and M2b Macrophage Polarization., Chen MM, Xiao X, Lao XM, Wei Y, Liu RX, Zeng QH, Wang JC, Ouyang FZ, Chen DP, Chan KW, Shi DC, Zheng L, Kuang DM., 2016
  • PD-1hi Identifies a Novel Regulatory B-cell Population in Human Hepatoma That Promotes Disease Progression., Xiao X, Lao XM, Chen MM, Liu RX, Wei Y, Ouyang FZ, Chen DP, Zhao XY, Zhao Q, Li XF, Liu CL, Zheng L, Kuang DM., 2016
  • Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma., Liu RX, Wei Y, Zeng QH, Chan KW, Xiao X, Zhao XY, Chen MM, Ouyang FZ, Chen DP, Zheng L, Lao XM, Kuang DM., 2015
  • B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets., Kuang DM, Xiao X, Zhao Q, Chen MM, Li XF, Liu RX, Wei Y, Ouyang FZ, Chen DP, Wu Y, Lao XM, Deng H, Zheng L., 2014
肿瘤 免疫学 B细胞 淋巴细胞 炎症 微环境 癌症 治疗 研究 生物学

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