Areas of Focus
- 与大脑发育、进化及相关疾病的基因解码与计算生物学研究
- 高通量测序数据的生物信息学方法开发;复杂生物系统的计算建模
Work Experience
- 2014-2017 - 博士后研究:耶鲁大学,生物统计系和神经生物学系
- 2017-2019 - 副研究科学家:耶鲁大学
- 2019至今 - 研究员:复旦大学,脑科学研究院
Academic Background & Achievements
- 2008 - 生物学学士学位:清华大学
- 2014 - 神经生物学博士学位:耶鲁大学
Publications
- Pianno: a probabilistic framework automating semantic annotation for spatial transcriptomics, Zhou Y, He W, Hou WZ, Zhu Y, 2024
- CellGO: a novel deep learning-based framework and webserver for cell-type-specific gene function interpretation, Li P, Wei J, Zhu Y, 2023
- MvPPT: a highly efficient and sensitive pathogenicity prediction tool for missense variants, Tong SY, Fan K, Zhou ZW, Liu LY, Zhang SQ, Fu Y, Wang GZ, Zhu Y, Yu YC, 2022
- Spatio-temporal transcriptomic divergence across human and macaque brain development, Zhu Y, Sousa AMM, Gao T, Skarica M, Li M, Santpere G, Esteller-Cucala P, Juan D, Ferrández-Peral L, Gulden FO, Yang M, Miller DJ, Marques-Bonet T, Kawasawa YI, Zhao H, Sestan N, 2018
- Molecular and cellular reorganization of neural circuits in the human lineage, Sousa AMM, Zhu Y, Raghanti MA, Kitchen RR, Onorati M, Tebbenkamp ATN, Stutz B, Meyer KA, Li M, Kawasawa YI, Liu F, Perez RG, Mele M, Carvalho T, Skarica M, Gulden FO, Pletikos M, Shibata A, Stephenson AR, Edles MK, Ely JJ, Elsworth JD, Horvath TL, Hof PR, Mane SM, Noonan JP, State MW, Lein ES, Knowles JA, Marques-Bonet T, Sherwood CC, Gerstein MB, Sestan N, 2017