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杨朝勇
Life Science
厦门大学
福建
Language: 英语, 中文
单细胞
时空
组学
测序
液体活检
微流控
核酸
智能设备
仪器
生物技术
Areas of Focus
- 单细胞时空组学测序
- 液体活检
- 微流控芯片
- 功能核酸
- 智能仪器与器件
Academic Background & Achievements
- 1998 - 学士学位: 厦门大学
- 2001 - 硕士学位: 厦门大学
- 2006 - 博士学位: 美国佛罗里达大学
- 2006-2007 - 博士后: 美国加州大学伯克利分校
Publications
- Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing., Cao, J; Zheng, Z; Sun, D; Chen, X; Cheng, R; Lv, T; An, Y; Zheng, J*; Song, J*; Wu, L*; Yang, C*, 2024
- mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq., Lin, X; Chen, Y; Lin, L; Yin, K; Cheng, R; Lin, X; Wang, X; Guo, Y; Wu, Z; Zhang, Y; Li, J*; Yang, C*; Song, J*, 2023
- Digital microfluidics-based digital counting of single-cell copy number variation (dd-scCNV Seq)., Yu, X, Ruan, W; Lin, F; Qian, W; Zou, Y; Liu, Y; Su, R; Niu, Q; Ruan, Q; Lin, W; Zhi Zhu, Zhang, H* ; Yang, C*, 2023
- Simultaneous subset tracing and miRNA profiling of tumor-derived exosomes via dual-surface-protein orthogonal barcoding., Lei, Y#, Fei, X#, Ding, Y; Zhang, J; Zhang, G; Dong, L; Song, J; Zhuo, Y; Xue, W; Zhang, P*; Yang, C*, 2023
- A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles., Zhang, G; Wang, Y; Zhou, W ; Lei, Y; Lu, J; Yin, W*; Zhu, Z*; Yang, C*; Zhang, P*, 2023
- Well-TEMP-seq as a microwell-based strategy for massively parallel profiling of single-cell temporal RNA dynamics., Lin,S; Yin, K; Zhang, Y; Lin, F; Chen, X; Zeng, X; Guo, X; Zhang, H; Song, J*; Yang, C*, 2023
- Metabolic Fluorine Labeling and Hotspot Imaging of Dynamic Gut Microbiota in Mice., Chen, D; Guo, J; Li, A; Sun, C; Lin, H; Lin, H; Yang, C*; Wang, W*; Gao, J*, 2023
- Insights of Life Molecules' Dynamic Distribution in Live Cells via Sequence-Structure Bispecific Fluorescent RNA., Chen, H; Su, M; Lei, Y ; Ye, Z; Chen, Z ; Ma, P ; Yuan, R* ; Zhuo, Y*; Yang, C*; Liang, W*, 2023
- Fluid Nanoporous Microinterface Enables Multiscale-Enhanced Affinity Interaction for Tumor-Derived Extracellular Vesicle Detection., Niu, Q; Gao, J; Zhao, K; Chen, X; Lin, X; Huang, C; An, Y; Xiao, X; Wu, Q; Cui, L*; Zhang, P*; Wu, L*; Yang, C*, 2022
- Deep transfer learning enables lesion tracing of circulating tumor cells., Guo, X; Lin, F; Yi, C; Song, J; Sun, D; Lin, L; Zhong, Z; Wu, Z; Wang, X; Zhang, Y; Li, J; Zhang, H*; Liu, F*; Yang, C*; Song, J*, 2022
- LINEAGE: Label-free identification of endogenous informative single-cell mitochondrial RNA mutation for lineage analysis., Lin, L; Zhang, Y; Qian, W; Liu, Y; Zhang, Y; Lin, F; Liu, C; Lu, G; Sun, D; Guo, X; Song, Y; Song, J*; Yang, C*; Li J*, 2022
- Fluid Nanoporous Microinterface Enables Multiscale-Enhanced Affinity Interaction for Tumor-Derived Extracellular Vesicle Detection., Niu, Q#; Gao, J#; Zhao, K#; Chen, X; Lin, X; Huang, C; An, Y; Xiao, X; Wu, Q; Cui, L*; Zhang, P*; Wu, L*; Yang, C*, 2022
- Aptamer-Based Detection of Circulating Targets for Precision Medicine., Wu, L; Wang, Y; Xu,X; Liu, Y; Lin, B; Zhang, M, Zhang, J; Wan, S; Yang, C*; Tan, W*, 2021
- Coupling Aptamer-based Protein Tagging with Metabolic Glycan Labeling for In Situ Visualization and Biological Function Study of Exosomal Protein-Specific Glycosylation., Zhu, L; Xu, Y; Wei, X; Lin, H; Huang, M; Lin, B; Song, Y*; Yang, C*, 2021
- Spherical Neutralizing Aptamer Inhibits SARS-CoV-2 Infection and Suppresses Mutational Escape., Sun, M; Liu, S; Song, T; Chen, F; Zhang, J; Huang, J; Wan, S; Lu, Y; Chen, H*; Tan, W*; Song, Y*; Yang, C*, 2021
- Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection., Sun, M; Liu, S; Wei, X; Wan, S; Huang, M; Song, T; Lu, Y; Weng, X; Lin, Z; Chen, H*; Song, Y*; Yang, C*, 2021
- Tracing Tumor-derived Exosomal PD-L1 by Dual-aptamer Activated Proximity-induced Droplet Digital PCR., Lin, B; Tian, T; Lu, Y; Liu, D; Huang, M; Zhu, L; Zhu, Z; Song, Y*; Yang, C*, 2021
- Highly Parallel and Efficient Single Cell mRNA Sequencing with Paired Picoliter Chambers., Zhang, M; Zou, Y; Xu, X; Zhang, X; Gao, M; Song, J; Huang, P; Chen, Q; Zhu, Z; Lin, W; Zare, R; Yang, C*, 2020
- Imaging Commensal Microbiota and Pathogenic Bacteria in the Gut., Lin, L; Du, Y; Song, J; Wang, W*; Yang, C*, 2021
- DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells., Zhang, J; Lin, B; Wu, L; Huang, M; Li, X; Zhang, H; Song, J; Wang, W; Zhao, G*; Song, Y*; Yang, C*, 2020
- Quantification of Bacterial Metabolic Activities in the Gut by D-Amino Acid-based in vivo Labeling., Lin, L; Song, J; Du, Y; Wu, Q; Gao, J; Song, Y; Yang, C*; Wang, W.*, 2020
- Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability., Wu, L; Ding, H; Qu, X; Shi, X; Yang, J; Huang, M; Zhang, J; Zhang, H; Song, J; Zhu, L; Song, Y*; Ma, Y*; Yang, C*, 2020
- Digital-WGS: Automated, Highly Efficient Whole-genome Sequencing of Single Cells by Digital Microfluidics., Ruan, Q; Ruan, W; Lin, X; Wang, Y; Zou, F; Zhou, L; Zhu, Z; Yang, C*, 2020
- Metabolic Labeling of Peptidoglycan with NIR-II Dye Enables in vivo Imaging of Gut Microbiota., Wang, W; Yang, Q; Du, Y, Zhou, X, Du, X, Wu, Q, Lin, L, Song, Y, Li, F, Yang, C*, Tan, W*, 2020
- Revealing the in vivo growth and division patterns of mouse gut bacteria., Lin, L; Wu, Q; Song, J; Du, Y; Gao, J; Song, Y; Wang, W*; Yang, C*, 2020
- Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction., Huang, M; Yang, J; Wang, T; Song, J; Xia, J; Wu, L; Wang, W; Wu, Q; Zhu, Z; Song, Y*; Yang, C*, 2020
- Three-dimensional Quantitative Imaging of Native Microbiota Distribution in the Gut., Wang, W*; Zhang, N; Du, Y; Gao, J; Li, M; Lin, L; Czajkowsky, D; Li, X*; Yang, C*; Shao, Z, 2021
- Assessing the Viability of Transplanted Gut Microbiota by Sequential Tagging with D-Amino acid-based Metabolic Probes., Wang, W; Lin, L; Du, Y; Song, Y; Peng, X; Chen, X*; Yang, C*, 2019
- Bioinspired Engineering of Multivalent Aptamer-Functionalized Nanointerface to Enhance Capture and Release of Circulating Tumor Cells., Song, Y; Shi, Y; Huang, M; Wang, W; Wang, Y; Cheng, J; Lei, Z; Zhu, Z; Yang, C*, 2019
- A Synthetic Light-Driven Substrate Channeling System for Precise Regulation of Enzyme Cascade Activity Based on DNA Origami., Chen, Y; Ke, G*; Ma, Y; Zhu, Z; Liu, M; Liu, Y; Yan, H*; Yang, C*, 2018
- Isolation, Detection and Antigen Based Profiling of Circulating Tumor Cells Using a Size Dictated Immunocapture Chip., Gashaw, M; Abate, M; Song, Y; Zhu, Z; Yan, F; Xu, Y; Wang, X; Li, Q; Yang, C*, 2017
- Hydrogel Droplet Microfluidics for High-Throughput Single Molecule/Cell Analysis., Zhu, Z; Yang, C*, 2017
- Directional Regulation of Enzyme Pathways through the Control of Substrate Channeling on a DNA Origami Scaffold., Ke, G; Liu, M; Jiang, S; Qi, X; Yang, YR; Wootten, S; Zhang, F; Zhu, Z; Liu, Y; Yang, C*; Yan, H*, 2016
- Au@Pt Nanoparticle Encapsulated Target-responsive Hydrogel with Volumetric Bar-chart Chip Readout for Quantitative Point-of-care Testing., Zhu Z; Guan, Z; Jia S; Lei Z; Lin, S; Zhang, H; Ma, Y; Tian, Z; Yang, C*, 2014
- A Multifunctional Nanomicelle for Real-Time Targeted Imaging and Precise Near-Infrared Therapy of Cancer., Tan, J; Ding, L; Ju, H*; Yang, Y; Li, X; Shen, Z; Zhu, Z; Yu, J*; Yang, C*, 2014
- Target-responsive “Sweet” Hydrogel with Glucometer Readout: an Effective Method for Portable and Quantitative Detection of Non-glucose Targets., Yan, L; Zhu, Z; Zou, Y; Huang, Y; Liu, D; Jia, S; Xu, D; Wu, M; Zhou, Y; Zhou, S; Yang, C*, 2013
- DNA Aptamer-mediated Cell Targeting., Xiong, X; Liu, H; Zhao, Z; Altman, M; Lopez-Colon, D; Yang, C*; Chang, L; Liu, C; Tan, W*, 2013
- L-DNA Molecular Beacons: A Safe, Stable, and Accurate Intracellular Nano-thermometer for Temperature Sensing in Living Cells., Ke, G; Wang, C; Ge Y; Zheng, N; Zhu Z; Yang, C*, 2012
- Self-assembly of a Bifunctional DNA Carrier for Drug Delivery., Wang, K; You, M; Chen, Y; Han, D; Zhu, Z; Huang, J; Williams, K; Yang, C*; Tan, W*, 2011
- Pyrene Excimer Probes for Nucleic Acids in Complex Biological Fluids Based on Hybridization Chain Reaction Amplification., Huang, J; Wu, Y; Chen, Y; Zhu, Z; Yang, X; Yang, C*; Wang, K*; Tan, W*, 2011
- Aptamer-Crosslinked Hydrogel as a Colorimetric Platform for Visual Detection., Zhu, Z; Wu, C; Liu, H; Zou, Y; Zhang, X; Kang, H; Yang, C*; Tan, W*, 2010
- Synthesis and Investigation of Deoxyribonucleic Acid/Locked Nucleic Acid Chimeric Molecular Beacons., Yang, C; Wang, L; Wu, Y; Kim, Y; Medley, C. D; Lin, H; Tan, W*, 2007
- Hybrid Molecular Probe for Nucleic Acid Analysis in Biological Samples., Yang, C; Martinez, K; Lin, H; Tan, W*, 2006
- TaqMan probe array for quantitative detection of DNA targets., Liu, H; Wang, H; Shi, Z; Wang, H; Yang, C; Silke, S; Tan, W; Lu, Z*, 2006
- Light-switching Excimer Probes for Rapid Protein Monitoring in Complex Biological Fluids., Yang, C; Jockusch, S; Vicens, M; Turro, N. J*; Tan, W*, 2005
- Molecular Assembly of Superquenchers in Signaling Molecular Interactions., Yang, C; Lin, H; Tan, W*, 2005
- Direct Synthesis of an Oligonucleotide-Poly(Phenylene Ethynylene) Conjugate with a Precise One-to-one Molecular Ratio., Yang, C; Pinto, M; Schanze, K; Tan, W*, 2005
Awards
- 美国化学会分析化学研究生奖
- 中国政府优秀自费留学生奖
- 中美化学与化学生物学教授协会杰出教授奖
- 福建省青年科技奖
- 福建省杰出青年基金
- 国家杰出青年科学基金
- 福建省高校领军人才
- 福建省科技创新领军人才
- 厦门市双百计划领军型创业人才
- 江苏省“双创人才”
- 英国皇家化学会会士
- 中国青年分析化学家奖
- 中国化学会-英国皇家化学会青年化学奖
- 科技部中青年科技创新领军人才
- 中组部等9部委《全民科学素质行动计划纲要》实施工作先进个人
- 福建省科技进步一等奖
- 美国化学会测量科学进展讲座奖
- 厦门市科技进步一等奖
