Professor | 吕晓雯 | 数字化转型顾问

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Name	吕晓雯
Contact Information	xiaowenlyu@xmu.edu.cn
Language ability	中文, 英文
Province	福建

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Name

吕晓雯

Contact Information

xiaowenlyu@xmu.edu.cn

Language ability

中文, 英文

Province

福建

University/Lab Affiliation and Title	厦门大学
Faculty	Medical
Academic Background & Achievements	2001-2005 理学学士生物技术专业: 南京农业大学 2005-2012 博士发育生物学专业: 中国科学院上海生物化学与细胞生物学研究所
Work Experience	2012-2013 助理教授: 中国科学院神经科学研究所 2014-2020 博士后研究员: 美国埃默里大学 2020-至今教授: 厦门大学医学院
Awards	厦门大学南强青年拔尖人才

University/Lab Affiliation and Title

厦门大学

Faculty

Medical

Academic Background & Achievements

2001-2005 理学学士生物技术专业: 南京农业大学
2005-2012 博士发育生物学专业: 中国科学院上海生物化学与细胞生物学研究所

Work Experience

2012-2013 助理教授: 中国科学院神经科学研究所
2014-2020 博士后研究员: 美国埃默里大学
2020-至今教授: 厦门大学医学院

Awards

厦门大学南强青年拔尖人才

Areas of Focus	染色质高维结构与功能胚胎干细胞定向分化
Publications	Regulation of CTCF loop formation during pancreatic cell differentiation, Lyu X, Rowley MJ, Kulik MJ, Dalton S & Corces VG, 2023 Priming with LSD1 inhibitors promotes the persistence and antitumor effect of adoptively transferred T cells, Qiu F, Jiang P, Zhang G, An j, Ruan K, Lyu X#, Zhou J#, Sheng W#, 2024 Replication timing maintains the global epigenetic state in human cells, Klein KN#, Zhao PA#, Lyu X#, Sasaki T, Bartlett DA, Singh AM, Tasan I, Zhang M, Watts LP, Hiraga S, Natsume T, Zhou X, Baslan T, Leung D, Kanemaki MT, Donaldson AD, Zhao H, Dalton S, Corces VG, Gilbert DM, 2021 Roles of Polycomb Complexes in the Reconstruction of 3D Genome Architecture during Preimplantation Embryonic Development, Yu L, Shen H, Lyu X, 2022 Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress, Lyu X, Rowley MJ, Corces VG, 2018 Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing, Li L#, Lyu X#, Hou C#, Takenaka N, Nguyen HQ, Ong CT, Cubeñas-Potts C, Hu M, Lei EP, Bosco G, Qin ZS, Corces VG, 2015 Engineering 3D genome organization, Lyu X, Corces VG, 2019 Genome-wide roles of Foxa2 in directing liver specification, Xu C#, Lu X#, Chen EZ, He Z, Uyunbilig B, Li G, Ma Y, Hui L, Xie B, Gao Y, Ding X, Hu Y, Hu P, Han JD*, Wang X, 2012 Condensin II Counteracts Cohesin and RNA Polymerase II in the Establishment of 3D Chromatin Organization, Rowley MJ, Lyu X, Rana V, Ando-Kuri M, Karns R, Bosco G, and Corces VG, 2019 Evolutionarily Conserved Principles Predict 3D Chromatin Organization, Rowley MJ#, Nichols MH#, Lyu X, Ando-Kuri M, Rivera ISM, Hermetz K, Wang P, Ruan Y, Corces VG, 2017 Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture, Cubeñas-Potts C#, Rowley MJ#, Lyu X, Li G, Lei EP, Corces VG, 2017 Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment, Wilson K#, Dileep V#, Marchal C, Lyu X, Li B, Axel P, Bartlett D, Qin Z, Robins AJ, Schulz TC, Corces VG, Gilbert DM, 2019 Chromatin States in Mouse Sperm Correlate with Embryonic and Adult Regulatory Landscapes, Jung Y, Sauria MEG, Lyu X, Cheema MS, Ausio J, Taylor J, Corces VG, 2017 Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming, Beagan JA, Gilgenast TG, Kim J, Plona Z, Norton HK, Hu G, Hsu SC, Shields EJ, Lyu X, Apostolou E, Hochedlinger K, Corces VG, Dekker J, Phillips-Cremins JE, 2016 Maintenance of CTCF- and transcription factor-mediated interactions from gametes to the early mouse embryo, Jung YH, Gold HB, Kremsky I, Rowley MJ, Punyawai K, Buonanotte A, Lyu X, Bixler BJ, Chan AWS, and Corces VG, 2019 Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb, Gutierrez-Perez I#, Rowley MJ#, Lyu X, Valadez-Graham V, Ballesta-Illan E, Lopez-Atalaya JP, Kremsky IJ, Vallejo DM, Caparros E, Corces VG, Dominguez M, 2019

Areas of Focus

染色质高维结构与功能
胚胎干细胞定向分化

Publications

Regulation of CTCF loop formation during pancreatic cell differentiation, Lyu X*, Rowley MJ, Kulik MJ, Dalton S & Corces VG*, 2023
Priming with LSD1 inhibitors promotes the persistence and antitumor effect of adoptively transferred T cells, Qiu F, Jiang P, Zhang G, An j, Ruan K, Lyu X#, Zhou J#, Sheng W#, 2024
Replication timing maintains the global epigenetic state in human cells, Klein KN#, Zhao PA#, Lyu X#, Sasaki T, Bartlett DA, Singh AM, Tasan I, Zhang M, Watts LP, Hiraga S, Natsume T, Zhou X, Baslan T, Leung D, Kanemaki MT, Donaldson AD, Zhao H, Dalton S, Corces VG, Gilbert DM, 2021
Roles of Polycomb Complexes in the Reconstruction of 3D Genome Architecture during Preimplantation Embryonic Development, Yu L, Shen H, Lyu X*, 2022
Architectural Proteins and Pluripotency Factors Cooperate to Orchestrate the Transcriptional Response of hESCs to Temperature Stress, Lyu X, Rowley MJ, Corces VG, 2018
Widespread rearrangement of 3D chromatin organization underlies polycomb-mediated stress-induced silencing, Li L#, Lyu X#, Hou C#, Takenaka N, Nguyen HQ, Ong CT, Cubeñas-Potts C, Hu M, Lei EP, Bosco G, Qin ZS, Corces VG, 2015
Engineering 3D genome organization, Lyu X, Corces VG, 2019
Genome-wide roles of Foxa2 in directing liver specification, Xu C#, Lu X#, Chen EZ, He Z, Uyunbilig B, Li G, Ma Y, Hui L, Xie B, Gao Y, Ding X, Hu Y, Hu P*, Han JD*, Wang X, 2012
Condensin II Counteracts Cohesin and RNA Polymerase II in the Establishment of 3D Chromatin Organization, Rowley MJ, Lyu X, Rana V, Ando-Kuri M, Karns R, Bosco G, and Corces VG, 2019
Evolutionarily Conserved Principles Predict 3D Chromatin Organization, Rowley MJ#, Nichols MH#, Lyu X, Ando-Kuri M, Rivera ISM, Hermetz K, Wang P, Ruan Y, Corces VG, 2017
Different enhancer classes in Drosophila bind distinct architectural proteins and mediate unique chromatin interactions and 3D architecture, Cubeñas-Potts C#, Rowley MJ#, Lyu X, Li G, Lei EP, Corces VG, 2017
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment, Wilson K#, Dileep V#, Marchal C, Lyu X, Li B, Axel P, Bartlett D, Qin Z, Robins AJ, Schulz TC, Corces VG, Gilbert DM, 2019
Chromatin States in Mouse Sperm Correlate with Embryonic and Adult Regulatory Landscapes, Jung Y, Sauria MEG, Lyu X, Cheema MS, Ausio J, Taylor J, Corces VG, 2017
Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming, Beagan JA, Gilgenast TG, Kim J, Plona Z, Norton HK, Hu G, Hsu SC, Shields EJ, Lyu X, Apostolou E, Hochedlinger K, Corces VG, Dekker J, Phillips-Cremins JE, 2016
Maintenance of CTCF- and transcription factor-mediated interactions from gametes to the early mouse embryo, Jung YH, Gold HB, Kremsky I, Rowley MJ, Punyawai K, Buonanotte A, Lyu X, Bixler BJ, Chan AWS, and Corces VG, 2019
Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb, Gutierrez-Perez I#, Rowley MJ#, Lyu X, Valadez-Graham V, Ballesta-Illan E, Lopez-Atalaya JP, Kremsky IJ, Vallejo DM, Caparros E, Corces VG, Dominguez M, 2019

染色质表观遗传基因表达增强子绝缘子干细胞分化转录基因组细胞命运

陈晓 - 浙江大学

Area of Focus
肌腱 | 韧带 | 再生 | 组织工程 | 干细胞 | 分化 | 软组织 | 运动系统 | 小分子 | 干预

张进 - 浙江大学

茵梓 - 浙江大学

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