Professor | 陈鑫 | 数字化转型顾问

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Name	陈鑫
Language ability	中文, 英文
Province	福建

Upload Avatar (500 x 500)

Name

陈鑫

Language ability

中文, 英文

Province

福建

University/Lab Affiliation and Title	厦门大学
Faculty	Medical
Academic Background & Achievements	2006年 - 学士学位: 厦门大学, 生命科学学院 2011年 - 博士学位: 中国科学院, 生物化学与细胞生物学研究所
Work Experience	2011-2018年 - 厦门大学, 生命科学学院 - 博士后 2018年至今 - 厦门大学, 生命科学学院 - 副教授

University/Lab Affiliation and Title

厦门大学

Faculty

Medical

Academic Background & Achievements

2006年 - 学士学位: 厦门大学, 生命科学学院
2011年 - 博士学位: 中国科学院, 生物化学与细胞生物学研究所

Work Experience

2011-2018年 - 厦门大学, 生命科学学院 - 博士后
2018年至今 - 厦门大学, 生命科学学院 - 副教授

Areas of Focus	坏死样凋亡和焦亡的分子机制细胞死亡在生理病理情况下的角色超高分辨率显微成像技术的生物医学成像
Publications	A Bifunctional Super-resolution Imaging Probe with Acidity-independent Lysosome-retention Mechanism, Xue Z, Wang S, Li J, Chen X, Han J, Han S, 2018 ISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility, Gao H, Yang Z, Wang X, Qian P, Hong R, Chen X, Su XZ, Cui H, Yuan J, 2018 RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis, Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J, 2018 Plasma membrane changes during programmed cell deaths, Zhang Y, Chen X, Gueydan C, Han J, 2018 RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, Zhang Y#, Su SS#, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J, 2017 MLKL channel in necroptosis is octamer formed by tetramers in a dyadic process, Huang D, Zheng X, Wang ZA, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J, 2017 Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis, Chen X#, He WT#, Hu L, Li J, Fang Y, Wang X, Xu X, Wang Z, Huang K, Han J, 2016 Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, Wu XN#, Yang ZH#, Wang XK, Zhang Y, Wan H, Song Y, Chen X, Shao J, Han J, 2014 Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death, Chen X#, Li W#, Ren J#, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J, 2014 Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase, Chen X#, Ma JJ#, Tan M, Yao P, Hu QH, Eriani G, Wang ED*, 2011

Areas of Focus

坏死样凋亡和焦亡的分子机制
细胞死亡在生理病理情况下的角色
超高分辨率显微成像技术的生物医学成像

Publications

A Bifunctional Super-resolution Imaging Probe with Acidity-independent Lysosome-retention Mechanism, Xue Z, Wang S, Li J, Chen X*, Han J, Han S*, 2018
ISP1-Anchored Polarization of GCβ/CDC50A Complex Initiates Malaria Ookinete Gliding Motility, Gao H, Yang Z, Wang X, Qian P, Hong R, Chen X, Su XZ, Cui H, Yuan J*, 2018
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis, Yang Z, Wang Y, Zhang Y, He X, Zhong CQ, Ni H, Chen X, Liang Y, Wu J, Zhao S, Zhou D, Han J*, 2018
Plasma membrane changes during programmed cell deaths, Zhang Y, Chen X, Gueydan C, Han J*, 2018
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, Zhang Y#, Su SS#, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J*, 2017
MLKL channel in necroptosis is octamer formed by tetramers in a dyadic process, Huang D, Zheng X, Wang ZA, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J*, 2017
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis, Chen X#, He WT#, Hu L, Li J, Fang Y, Wang X, Xu X, Wang Z, Huang K, Han J*, 2016
Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, Wu XN#, Yang ZH#, Wang XK, Zhang Y, Wan H, Song Y, Chen X, Shao J, Han J*, 2014
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death, Chen X#, Li W#, Ren J#, Huang D, He WT, Song Y, Yang C, Li W, Zheng X, Chen P, Han J*, 2014
Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase, Chen X#, Ma JJ#, Tan M, Yao P, Hu QH, Eriani G, Wang ED*, 2011

坏死样凋亡焦亡细胞死亡分子机制生理条件病理条件超高分辨率显微镜生物医学成像细胞生物学凋亡

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