Areas of Focus
- 生物大分子的相分离及其在神经退行性疾病中的应用
Work Experience
- 2014-2020 - 得克萨斯大学西南医学中心 - 博士后
- 2020-2023 - 清华大学生命科学学院 - 助理教授
- 2024-至今 - 清华大学生命科学学院 - 副教授
- 2020-至今 - 清华-IDG/麦戈文脑科学研究院、清华-北大生命科学联合中心 - 研究员
Academic Background & Achievements
- 2005-2009 学士：江南大学
- 2009-2014 博士：马凯特大学
Publications
- Phase separation as a possible mechanism for dosage sensitivity, Liang Yang, Jiali Lyu, Xi Li, Gaigai Guo, Xueya Zhou, Taoyu Chen, Yi Lin, Tingting Li, 2024
- Condensation matters, Ke Ruan, Yi Lin, Peiguo Yang, Wen Zhou, 2023
- Abnormal phase separation of biomacromolecules in human diseases, Songhao Zhang, Gaofeng Pei, Boya Li, Pilong Li, Yi Lin, 2023
- Circadian clocks are modulated by compartmentalized oscillating translation, Yanrong Zhuang, Zhiyuan Li, Shiyue Xiong, Chujie Sun, Boya Li, Shuangcheng Alivia Wu, Jiali Lyu, Xiang Shi, Liang Yang, Yutong Chen, Zhangbin Bao, Xi Li, Chuhanwen Sun, Yuling Chen, Haiteng Deng, Tingting Li, Qingfeng Wu, Ling Qi, Yue Huang, Xuerui Yang, Yi Lin, 2023
- The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes, Shuangcheng Alivia Wu, Chenchen Shen, Xiaoqiong Wei, Xiawei Zhang, Siwen Wang, Xinxin Chen, Mauricio Torres, You Lu, Liangguang Leo Lin, Huilun Helen Wang, Allen H Hunter, Deyu Fang, Shengyi Sun, Magdalena I Ivanova, Yi Lin, Ling Qi, 2023
- Recruitment of TRIM33 to cell-context specific PML nuclear bodies regulates nodal signaling in mESCs, Hongyao Sun, Yutong Chen, Kun Yan, Yanqiu Shao, Qiangfeng C Zhang, Yi Lin, Qiaoran Xi, 2023
- A brief guideline for studies of phase-separated biomolecular condensates, Yifei Gao, Xi Li, Pilong Li, Yi Lin, 2022
- Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset, Xiang Shi, Yanrong Zhuang, Zhenhua Chen, Mingrui Xu, Junqi Kuang, Xue-Lian Sun, Lisen Gao, Xia Kuang, Huairen Zhang, Wei Li, Samuel Zheng Hao Wong, Chuanyu Liu, Longqi Liu, Danhua Jiang, Duanqing Pei, Yi Lin, QingFeng Wu, 2022
- Phase separation in RNA biology, Yi Lin, Xiaofeng Fang, 2021
- Redox-mediated regulation of an evolutionarily conserved cross-beta structure formed by the TDP43 LC domain, Yi Lin, Xiaoming Zhou, Masato Kato, Daifei Liu, Sina Ghaemmaghami, Benjamin P Tu, Steven L McKnight, 2020
- Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains, Dylan T Murray, Masato Kato, Yi Lin, Kent R Thurber, Ivan Hung, Steven L McKnight, Robert Tycko, 2017
- Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers, Yi Lin, Eiichiro Mori, Masato Kato, Siheng Xiang, Leeju Wu, Ilmin Kwon, Steven L McKnight, 2016
Awards
- Oliver Smith 学术成就奖 (2013)
- 马凯特大学奖学金 (2012-2014)
- Richard W. Jobling 奖 (2012-2013)
