Professor | 韩蕾 | 数字化转型顾问

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Name	韩蕾
Contact Information	hanleibio2005@gmail.com
Language ability	中文, 英语
Province	湖北省

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Name

韩蕾

Contact Information

hanleibio2005@gmail.com

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005-2009 北京化工大学生命科学与技术学院生物工程专业本科生 2009-2012 中国农业科学院植物保护研究所生物化学与分子生物学专业硕士研究生 2012-2017 中国科学院生物物理研究所生物化学与分子生物学专业博士研究生
Work Experience	2017-2023 斯坦福大学分子细胞生理系博士后 2023-至今武汉大学泰康医学院（基础医学院）教授，泰康生命医学中心PI
Awards	斯坦福大学医学院院长博士后奖学金 (2019) 国家级人才计划入选者

University/Lab Affiliation and Title

武汉大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2005-2009 北京化工大学生命科学与技术学院生物工程专业本科生
2009-2012 中国农业科学院植物保护研究所生物化学与分子生物学专业硕士研究生
2012-2017 中国科学院生物物理研究所生物化学与分子生物学专业博士研究生

Work Experience

2017-2023 斯坦福大学分子细胞生理系博士后
2023-至今武汉大学泰康医学院（基础医学院）教授，泰康生命医学中心PI

Awards

斯坦福大学医学院院长博士后奖学金 (2019)
国家级人才计划入选者

Areas of Focus	跨膜转运蛋白转运调控机制以及药物开发研究与重大疾病相关的重要代谢物转运蛋白，药物靶点研究潜力
Publications	Structure and mechanism of the alkane-oxidizing enzyme AlkB, Xue Guo, Jianxiu Zhang, Lei Han, Juliet Lee, Shoshana C Williams, Allison Forsberg, Yan Xu, Rachel Narehood Austin, Liang Feng, 2023 Structure and mechanism of the SGLT family of glucose transporters, Lei Han, Qianhui Qu, Deniz Aydin, Ouliana Panova, Michael J Robertson, Yan Xu, Ron O Dror, Georgios Skiniotis, Liang Feng, 2022 Molecular mechanism of substrate recognition and transport by the AtSWEET13 sugar transporter, Lei Han, Yongping Zhu, Min Liu, Ye Zhou, Guangyuan Lu, Lan Lan, Xianping Wang, Yongfang Zhao, Xuejun C Zhang, 2017 Energy coupling mechanisms of AcrB-like RND transporters, Xuejun C Zhang, Min Liu, Lei Han, 2017 The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2, Ruimin Zhou, Tong Zhu, Lei Han, Mengjie Liu, Mengyuan Xu, Yanli Liu, Dandan Han, Dewen Qiu, Qingqiu Gong, Xinqi Liu, 2017 Uniporter substrate binding and transport: reformulating mechanistic questions, Xuejun C Zhang, Lei Han, 2016 How does a beta-barrel integral membrane protein insert into the membrane?, Xuejun C Zhang, Lei Han, 2016 How does the chemical potential of the substrate drive a uniporter?, Xuejun C Zhang, Lei Han, 2016 Thermodynamics of ABC transporters, Xuejun C Zhang, Lei Han, Yan Zhao, 2016 Purification, crystallization and preliminary X-ray diffraction analysis of the effector protein PevD1 from Verticillium dahliae, Lei Han, Zheng Liu, Xinqi Liu, Dewen Qiu, 2012 Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60, Jing Zhao, Lihua Guo, Hongmei Zeng, Xiufen Yang, Jingjing Yuan, Huaixing Shi, Yehui Xiong, Mingjia Chen, Lei Han, Dewen Qiu, 2012

Areas of Focus

跨膜转运蛋白转运调控机制以及药物开发研究
与重大疾病相关的重要代谢物转运蛋白，药物靶点研究潜力

Publications

Structure and mechanism of the alkane-oxidizing enzyme AlkB, Xue Guo, Jianxiu Zhang, Lei Han, Juliet Lee, Shoshana C Williams, Allison Forsberg, Yan Xu, Rachel Narehood Austin, Liang Feng, 2023
Structure and mechanism of the SGLT family of glucose transporters, Lei Han, Qianhui Qu, Deniz Aydin, Ouliana Panova, Michael J Robertson, Yan Xu, Ron O Dror, Georgios Skiniotis, Liang Feng, 2022
Molecular mechanism of substrate recognition and transport by the AtSWEET13 sugar transporter, Lei Han, Yongping Zhu, Min Liu, Ye Zhou, Guangyuan Lu, Lan Lan, Xianping Wang, Yongfang Zhao, Xuejun C Zhang, 2017
Energy coupling mechanisms of AcrB-like RND transporters, Xuejun C Zhang, Min Liu, Lei Han, 2017
The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2, Ruimin Zhou, Tong Zhu, Lei Han, Mengjie Liu, Mengyuan Xu, Yanli Liu, Dandan Han, Dewen Qiu, Qingqiu Gong, Xinqi Liu, 2017
Uniporter substrate binding and transport: reformulating mechanistic questions, Xuejun C Zhang, Lei Han, 2016
How does a beta-barrel integral membrane protein insert into the membrane?, Xuejun C Zhang, Lei Han, 2016
How does the chemical potential of the substrate drive a uniporter?, Xuejun C Zhang, Lei Han, 2016
Thermodynamics of ABC transporters, Xuejun C Zhang, Lei Han, Yan Zhao, 2016
Purification, crystallization and preliminary X-ray diffraction analysis of the effector protein PevD1 from Verticillium dahliae, Lei Han, Zheng Liu, Xinqi Liu, Dewen Qiu, 2012
Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60, Jing Zhao, Lihua Guo, Hongmei Zeng, Xiufen Yang, Jingjing Yuan, Huaixing Shi, Yehui Xiong, Mingjia Chen, Lei Han, Dewen Qiu, 2012

跨膜转运蛋白药物开发底物转运蛋白构象膜电位代谢转运疾病关联结构生物学高通量筛选

范成鹏 - 武汉大学

仓春蕾 - 中国科学技术大学

Area of Focus
溶酶体膜 | 离子通道 | 调制 | 信号转导 | 细胞器 | 疾病机理 | 药物开发 | 钾通道 | 钠通道 | 膜电位

仓春蕾 - 中国科学技术大学

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