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梁征宇
Life Science
南方科技大学
广东省
Language: 中文, 英语
基因组学
三维基因组
转录
Rna
癌症
染色体外Dna
生物信息学
分子生物学
基因调控
染色质
Areas of Focus
- 三维基因组的检测技术开发和功能研究
- 转录调控机制研究
- RNA代谢及参与基因组功能研究
- 肿瘤中染色体外DNA的结构与功能研究
Work Experience
- 2018.9-2023.4 - 加州大学圣地亚哥分校，细胞与分子医学系，博士后
- 2023.4-至今 - 南方科技大学，系统生物学系，助理教授
Academic Background & Achievements
- 2008-2012 生物信息技术学士：华中科技大学
- 2012-2018 生物学博士：清华大学（导师：张奇伟教授）
Publications
- Pervasive chromatin-RNA binding protein interactions enable RNA-based regulation of transcription, Xiao, R.*, Chen, J.-Y.*, Liang, Z.*, Luo, D., Chen, G., Lu, Z.J., Chen, Y., Zhou, B., Li, H., and Du, X., 2019
- BL-Hi-C is an efficient and sensitive approach for capturing structural and regulatory chromatin interactions, Liang, Z., Li, G., Wang, Z., Djekidel, M.N., Li, Y., Qian, M.-P., Zhang, M.Q., and Chen, Y., 2017
- 3D genome encoded by LINE and SINE repeats, Liang, Z., and Fu, X.-D., 2021
- PRDM16 is a compact myocardium-enriched transcription factor required to maintain compact myocardial cardiomyocyte identity in left ventricle, Wu, T.*, Liang, Z.*, Zhang, Z., Liu, C., Zhang, L., Gu, Y., Peterson, K.L., Evans, S.M., Fu, X.-D., and Chen, J., 2022
- CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming, Song, Y.*, Liang, Z.*, Zhang, J.*, Hu, G.*, Wang, J., Li, Y., Guo, R., Dong, X., Babarinde, I.A., and Ping, W., 2022
- Reversing a model of Parkinson’s disease with in situ converted nigral neurons, Qian, H., Kang, X., Hu, J., Zhang, D., Liang, Z., Meng, F., Zhang, X., Xue, Y., Maimon, R., and Dowdy, S.F., 2020
- Initiation of parental genome reprogramming in fertilized oocyte by splicing kinase SRPK1-catalyzed protamine phosphorylation, Gou, L.-T., Lim, D.-H., Ma, W., Aubol, B.E., Hao, Y., Wang, X., Zhao, J., Liang, Z., Shao, C., and Zhang, X., 2020
- Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem CellsTargeting Transcription Machinery Potentiates Immunotherapy, Qiu, Z., Zhao, L., Shen, J.Z., Liang, Z., Wu, Q., Yang, K., Min, L., Gimple, R.C., Yang, Q., and Bhargava, S., 2022
- Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy, Zhu, S., Nguyen, A., Pang, J., Zhao, J., Chen, Z.e., Liang, Z., Gu, Y., Huynh, H., Bao, Y., and Lee, S., 2022
