Professor | 梁征宇 | 数字化转型顾问

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Name	梁征宇
Contact Information	liangzy@sustech.edu.cn
Language ability	中文, 英语
Province	广东省

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Name

梁征宇

Contact Information

liangzy@sustech.edu.cn

Language ability

中文, 英语

Province

广东省

University/Lab Affiliation and Title	南方科技大学
Faculty	Life Sciences
Academic Background & Achievements	2008-2012 生物信息技术学士：华中科技大学 2012-2018 生物学博士：清华大学（导师：张奇伟教授）
Work Experience	2018.9-2023.4 - 加州大学圣地亚哥分校，细胞与分子医学系，博士后 2023.4-至今 - 南方科技大学，系统生物学系，助理教授

University/Lab Affiliation and Title

南方科技大学

Faculty

Life Sciences

Academic Background & Achievements

2008-2012 生物信息技术学士：华中科技大学
2012-2018 生物学博士：清华大学（导师：张奇伟教授）

Work Experience

2018.9-2023.4 - 加州大学圣地亚哥分校，细胞与分子医学系，博士后
2023.4-至今 - 南方科技大学，系统生物学系，助理教授

Areas of Focus	三维基因组的检测技术开发和功能研究转录调控机制研究 RNA代谢及参与基因组功能研究肿瘤中染色体外DNA的结构与功能研究
Publications	Pervasive chromatin-RNA binding protein interactions enable RNA-based regulation of transcription, Xiao, R., Chen, J.-Y., Liang, Z., Luo, D., Chen, G., Lu, Z.J., Chen, Y., Zhou, B., Li, H., and Du, X., 2019 BL-Hi-C is an efficient and sensitive approach for capturing structural and regulatory chromatin interactions, Liang, Z., Li, G., Wang, Z., Djekidel, M.N., Li, Y., Qian, M.-P., Zhang, M.Q., and Chen, Y., 2017 3D genome encoded by LINE and SINE repeats, Liang, Z., and Fu, X.-D., 2021 PRDM16 is a compact myocardium-enriched transcription factor required to maintain compact myocardial cardiomyocyte identity in left ventricle, Wu, T., Liang, Z., Zhang, Z., Liu, C., Zhang, L., Gu, Y., Peterson, K.L., Evans, S.M., Fu, X.-D., and Chen, J., 2022 CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming, Song, Y., Liang, Z., Zhang, J., Hu, G.*, Wang, J., Li, Y., Guo, R., Dong, X., Babarinde, I.A., and Ping, W., 2022 Reversing a model of Parkinson’s disease with in situ converted nigral neurons, Qian, H., Kang, X., Hu, J., Zhang, D., Liang, Z., Meng, F., Zhang, X., Xue, Y., Maimon, R., and Dowdy, S.F., 2020 Initiation of parental genome reprogramming in fertilized oocyte by splicing kinase SRPK1-catalyzed protamine phosphorylation, Gou, L.-T., Lim, D.-H., Ma, W., Aubol, B.E., Hao, Y., Wang, X., Zhao, J., Liang, Z., Shao, C., and Zhang, X., 2020 Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem CellsTargeting Transcription Machinery Potentiates Immunotherapy, Qiu, Z., Zhao, L., Shen, J.Z., Liang, Z., Wu, Q., Yang, K., Min, L., Gimple, R.C., Yang, Q., and Bhargava, S., 2022 Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy, Zhu, S., Nguyen, A., Pang, J., Zhao, J., Chen, Z.e., Liang, Z., Gu, Y., Huynh, H., Bao, Y., and Lee, S., 2022

Areas of Focus

三维基因组的检测技术开发和功能研究
转录调控机制研究
RNA代谢及参与基因组功能研究
肿瘤中染色体外DNA的结构与功能研究

Publications

Pervasive chromatin-RNA binding protein interactions enable RNA-based regulation of transcription, Xiao, R.*, Chen, J.-Y.*, Liang, Z.*, Luo, D., Chen, G., Lu, Z.J., Chen, Y., Zhou, B., Li, H., and Du, X., 2019
BL-Hi-C is an efficient and sensitive approach for capturing structural and regulatory chromatin interactions, Liang, Z., Li, G., Wang, Z., Djekidel, M.N., Li, Y., Qian, M.-P., Zhang, M.Q., and Chen, Y., 2017
3D genome encoded by LINE and SINE repeats, Liang, Z., and Fu, X.-D., 2021
PRDM16 is a compact myocardium-enriched transcription factor required to maintain compact myocardial cardiomyocyte identity in left ventricle, Wu, T.*, Liang, Z.*, Zhang, Z., Liu, C., Zhang, L., Gu, Y., Peterson, K.L., Evans, S.M., Fu, X.-D., and Chen, J., 2022
CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming, Song, Y.*, Liang, Z.*, Zhang, J.*, Hu, G.*, Wang, J., Li, Y., Guo, R., Dong, X., Babarinde, I.A., and Ping, W., 2022
Reversing a model of Parkinson’s disease with in situ converted nigral neurons, Qian, H., Kang, X., Hu, J., Zhang, D., Liang, Z., Meng, F., Zhang, X., Xue, Y., Maimon, R., and Dowdy, S.F., 2020
Initiation of parental genome reprogramming in fertilized oocyte by splicing kinase SRPK1-catalyzed protamine phosphorylation, Gou, L.-T., Lim, D.-H., Ma, W., Aubol, B.E., Hao, Y., Wang, X., Zhao, J., Liang, Z., Shao, C., and Zhang, X., 2020
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem CellsTargeting Transcription Machinery Potentiates Immunotherapy, Qiu, Z., Zhao, L., Shen, J.Z., Liang, Z., Wu, Q., Yang, K., Min, L., Gimple, R.C., Yang, Q., and Bhargava, S., 2022
Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy, Zhu, S., Nguyen, A., Pang, J., Zhao, J., Chen, Z.e., Liang, Z., Gu, Y., Huynh, H., Bao, Y., and Lee, S., 2022

基因组学三维基因组转录 Rna 癌症染色体外Dna 生物信息学分子生物学基因调控染色质

王丽君 - 上海大学

Area of Focus
表观遗传学 | 心血管 | 健康 | 运动 | Rna | 疾病机制 | 分子生物学 | 干预 | Rna修饰 | 研究

朱柳村 - 上海大学

冯畅 - 上海大学

Area of Focus
生物标志物 | 癌症 | 检测 | 诊断 | Dna | Rna | 放大 | 分子生物学 | 生物化学 | 临床研究

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