Professor | 赵燕 | 数字化转型顾问

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Name	赵燕
Contact Information	zhaoyan@sustech.edu.cn
Language ability	中文, 英语
Province	广东省

Upload Avatar (500 x 500)

Name

赵燕

Contact Information

zhaoyan@sustech.edu.cn

Language ability

中文, 英语

Province

广东省

University/Lab Affiliation and Title	南方科技大学
Faculty	Life Sciences
Academic Background & Achievements	本科和博士：北京大学医学部在中国科学院生物物理所和美国马萨诸塞大学医学院进行博士后工作基金委优秀青年科学基金获得者
Work Experience	2020 - 至今：南方科技大学，副教授

University/Lab Affiliation and Title

南方科技大学

Faculty

Life Sciences

Academic Background & Achievements

本科和博士：北京大学医学部
在中国科学院生物物理所和美国马萨诸塞大学医学院进行博士后工作
基金委优秀青年科学基金获得者

Work Experience

2020 - 至今：南方科技大学，副教授

Areas of Focus	细胞自噬的分子机制和生理功能多细胞生物中的自噬神经退行性疾病和潜在治疗靶点内质网与自噬前体结构的相互作用神经细胞自噬的分子机制冠状病毒转录复制过程中双层膜囊泡的形成机制
Publications	LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation, Li, M., Hou, Y., Zhou, Y., Yang, Z., Zhao, H., Jian, T., Yu, Q., Zeng, F., Liu, X., Zhang, Z., and Zhao, Y.G., 2024 VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection, Ji, M., Li, M., Sun, L., Zhao, H., Li, Y., Zhou, L., Yang, Z., Zhao, X., Qu, W., Xue, H., Zheng, Z., Li, Y., Deng, H., and Zhao, Y.G., 2022 β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells, Ji, C., Zhao, H., Zhang, H., and Zhao, Y.G., 2021 Role of Wdr45b in maintaining neural autophagy and cognitive function, Ji, C., Zhao, H., Li, D., Sun, H., Hao, J., Chen, R., Wang, X., Zhang, H., and Zhao, Y.G., 2020 The ER-localized protein DFCP1 modulates ER-lipid droplet contact formation, Li, D., Zhao, Y.G., Li, D., Zhao, H., Huang, J., Miao, G., Feng, D., Liu, P., Li, D., and Zhang, H., 2019 The ER contact proteins VAPA/B interact with multiple autophagy proteins to modulate autophagosome biogenesis, Zhao, Y.G., Liu, N., Miao, G., Chen, Y., Zhao, H., and Zhang, H., 2018 The ER-localized transmembrane protein EPG-3/VMP1 regulates SERCA activity to control ER-isolation membrane contacts for autophagosome formation, Zhao, Y.G., Chen, Y., Miao, G., Zhao, H., Qu, W., Li, D., Wang, Z., Liu, N., Li, L., Chen, S., Liu, P., Feng, D., and Zhang, H., 2017 The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis, Zhao, Y.G., Sun, L., Miao, G.Y., Ji, C.C., Zhao, H.Y., Sun, H.Y., Miao, L., Yoshii, S.R., Mizushima, N., Wang X.Q., and Zhang, H., 2015 Role of Epg5 in selective neurodegeneration and Vici syndrome, Zhao, Y.G., Zhao, H.Y., Sun, H.Y., and Zhang, H., 2013 Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration, Zhao, H.Y., Zhao, Y.G., Wang, X.W., Xu, L.J., Miao, L., Feng, D., Chen, Q., Kovács, A.L. Fan, D.S., and Zhang, H., 2013 The p53-induced gene Ei24 is an essential component of the basal autophagy pathway, Zhao, Y.G., Zhao, H.Y., Miao, L., Wang, L., Sun, F., and Zhang, H., 2012

Areas of Focus

细胞自噬的分子机制和生理功能
多细胞生物中的自噬
神经退行性疾病和潜在治疗靶点
内质网与自噬前体结构的相互作用
神经细胞自噬的分子机制
冠状病毒转录复制过程中双层膜囊泡的形成机制

Publications

LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation, Li, M., Hou, Y., Zhou, Y., Yang, Z., Zhao, H., Jian, T., Yu, Q., Zeng, F., Liu, X., Zhang, Z., and Zhao, Y.G., 2024
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection, Ji, M., Li, M., Sun, L., Zhao, H., Li, Y., Zhou, L., Yang, Z., Zhao, X., Qu, W., Xue, H., Zheng, Z., Li, Y., Deng, H., and Zhao, Y.G., 2022
β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells, Ji, C., Zhao, H., Zhang, H., and Zhao, Y.G., 2021
Role of Wdr45b in maintaining neural autophagy and cognitive function, Ji, C., Zhao, H., Li, D., Sun, H., Hao, J., Chen, R., Wang, X., Zhang, H., and Zhao, Y.G., 2020
The ER-localized protein DFCP1 modulates ER-lipid droplet contact formation, Li, D., Zhao, Y.G., Li, D., Zhao, H., Huang, J., Miao, G., Feng, D., Liu, P., Li, D., and Zhang, H., 2019
The ER contact proteins VAPA/B interact with multiple autophagy proteins to modulate autophagosome biogenesis, Zhao, Y.G., Liu, N., Miao, G., Chen, Y., Zhao, H., and Zhang, H., 2018
The ER-localized transmembrane protein EPG-3/VMP1 regulates SERCA activity to control ER-isolation membrane contacts for autophagosome formation, Zhao, Y.G., Chen, Y., Miao, G., Zhao, H., Qu, W., Li, D., Wang, Z., Liu, N., Li, L., Chen, S., Liu, P., Feng, D., and Zhang, H., 2017
The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis, Zhao, Y.G., Sun, L., Miao, G.Y., Ji, C.C., Zhao, H.Y., Sun, H.Y., Miao, L., Yoshii, S.R., Mizushima, N., Wang X.Q., and Zhang, H., 2015
Role of Epg5 in selective neurodegeneration and Vici syndrome, Zhao, Y.G., Zhao, H.Y., Sun, H.Y., and Zhang, H., 2013
Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration, Zhao, H.Y., Zhao, Y.G., Wang, X.W., Xu, L.J., Miao, L., Feng, D., Chen, Q., Kovács, A.L. Fan, D.S., and Zhang, H., 2013
The p53-induced gene Ei24 is an essential component of the basal autophagy pathway, Zhao, Y.G., Zhao, H.Y., Miao, L., Wang, L., Sun, F., and Zhang, H., 2012

自噬细胞稳定性分子机制生理功能神经退行性疾病治疗靶点内质网自噬前体神经细胞冠状病毒

范亮亮 - 中南大学

Area of Focus
心血管疾病 | 呼吸系统疾病 | 遗传因素 | 致病 | 分子机制 | 鉴定 | 研究 | 内质网 | 线粒体 | 细胞器

刘剑淼 - 华中科技大学

郑鹏里 - 北京大学

Area of Focus
内质网 | 线粒体 | 膜细胞器 | 动态 | 互作 | 分子机制 | 人类疾病 | 神经退行性疾病 | 形态 | 功能

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