Upload Avatar (500 x 500)
赵燕
Life Science
南方科技大学
广东省
Language: 中文, 英语
自噬
细胞稳定性
分子机制
生理功能
神经退行性疾病
治疗靶点
内质网
自噬前体
神经细胞
冠状病毒
Areas of Focus
- 细胞自噬的分子机制和生理功能
- 多细胞生物中的自噬
- 神经退行性疾病和潜在治疗靶点
- 内质网与自噬前体结构的相互作用
- 神经细胞自噬的分子机制
- 冠状病毒转录复制过程中双层膜囊泡的形成机制
Work Experience
- 2020 - 至今：南方科技大学，副教授
Academic Background & Achievements
- 本科和博士：北京大学医学部
- 在中国科学院生物物理所和美国马萨诸塞大学医学院进行博士后工作
- 基金委优秀青年科学基金获得者
Publications
- LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation, Li, M., Hou, Y., Zhou, Y., Yang, Z., Zhao, H., Jian, T., Yu, Q., Zeng, F., Liu, X., Zhang, Z., and Zhao, Y.G., 2024
- VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection, Ji, M., Li, M., Sun, L., Zhao, H., Li, Y., Zhou, L., Yang, Z., Zhao, X., Qu, W., Xue, H., Zheng, Z., Li, Y., Deng, H., and Zhao, Y.G., 2022
- β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells, Ji, C., Zhao, H., Zhang, H., and Zhao, Y.G., 2021
- Role of Wdr45b in maintaining neural autophagy and cognitive function, Ji, C., Zhao, H., Li, D., Sun, H., Hao, J., Chen, R., Wang, X., Zhang, H., and Zhao, Y.G., 2020
- The ER-localized protein DFCP1 modulates ER-lipid droplet contact formation, Li, D., Zhao, Y.G., Li, D., Zhao, H., Huang, J., Miao, G., Feng, D., Liu, P., Li, D., and Zhang, H., 2019
- The ER contact proteins VAPA/B interact with multiple autophagy proteins to modulate autophagosome biogenesis, Zhao, Y.G., Liu, N., Miao, G., Chen, Y., Zhao, H., and Zhang, H., 2018
- The ER-localized transmembrane protein EPG-3/VMP1 regulates SERCA activity to control ER-isolation membrane contacts for autophagosome formation, Zhao, Y.G., Chen, Y., Miao, G., Zhao, H., Qu, W., Li, D., Wang, Z., Liu, N., Li, L., Chen, S., Liu, P., Feng, D., and Zhang, H., 2017
- The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis, Zhao, Y.G., Sun, L., Miao, G.Y., Ji, C.C., Zhao, H.Y., Sun, H.Y., Miao, L., Yoshii, S.R., Mizushima, N., Wang X.Q., and Zhang, H., 2015
- Role of Epg5 in selective neurodegeneration and Vici syndrome, Zhao, Y.G., Zhao, H.Y., Sun, H.Y., and Zhang, H., 2013
- Mice deficient in Epg5 exhibit selective neuronal vulnerability to degeneration, Zhao, H.Y., Zhao, Y.G., Wang, X.W., Xu, L.J., Miao, L., Feng, D., Chen, Q., Kovács, A.L. Fan, D.S., and Zhang, H., 2013
- The p53-induced gene Ei24 is an essential component of the basal autophagy pathway, Zhao, Y.G., Zhao, H.Y., Miao, L., Wang, L., Sun, F., and Zhang, H., 2012
