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胡宏岗
Medicine
上海大学
上海
Language: 中文, 英语
多肽
蛋白质
药物开发
材料科学
技术应用
生物医学工程
治疗学
分子设计
生物化学
药理学
Areas of Focus
- 多肽（蛋白）药物和材料共性技术开发及应用
Work Experience
- 2008 - 至今：第二军医大学，教授
- 2018 - 至今：上海大学，教授
Academic Background & Achievements
- 2003 - 药学学士学位：第二军医大学
- 2008 - 药物化学博士学位：第二军医大学
- 在权威期刊上发表了100多篇论文
- 编写了8本专著和教材
- 拥有30多项国家专利
Publications
- Configuration-specific antibody for bacterial heptosylation: An antiadhesion therapeutic strategy, Li X, Liao C, Xu Y, Lu QH, Chen S, Su L, Zou Y, Shao F, Lu W, Zhang WD, Hu HG, 2023
- A robust protein-peptide co-assembling nanoformulation (PePCAN) platform with significant cell-entry characteristics for targeted cancer therapy, Zhao X, Li X, Li B, Sun Y, Shi Y, Shen H, Wang F, Li J, Sharopov F, Mukhiddinov Z, Ma C, Liu K, Hu HG, 2023
- Design of stapled peptide-based PROTACs for MDM2/MDMX atypical degradation and tumor suppression, Chen S, Li X, Li Y, Yuan X, Geng C, Gao S, Li J, Ma B, Wang Z, Lu W, Hu HG, 2022
- A bifunctional molecule-assisted synthesis of mimics for use in probing the ubiquitination system, Zheng Q, Wang T, Mao J, Chu G, Liang L, Jing Y, Zuo C, Yu Y, Hu HG, Pan M, 2022
- Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression, Li X, Gohain N, Chen S, Li Y, Zhao X, Li B, Tolbert WD, He W, Pazgier M, Hu HG, Lu W, 2021
- Stapled Helical Peptides Bearing Different Anchoring Residues, Li X, Chen S, Zhang WD, Hu HG, 2020
- A PROTAC peptide induces durable β-catenin degradation and suppresses Wnt-dependent intestinal cancer, Liao H, Li X, Zhao L, Wang Y, Wang X, Wu Y, Zhou X, Fu W, Liu L, Hu HG, Chen YG, 2020
- Robust Biological Fibers Based on Widely Available Proteins: Facile Fabrication and Suturing Application, Zhang JR, Sun J, Li B, Yang CJ, Shen JL, Wang N, Gu R, Wang DG, Chen D, Hu HG, Fan CH, Zhang HJ, Liu K, 2020
- A Highly Efficient Synthesis of Polyubiquitin Chains, Qu Q, Pan M, Gao S, Zheng QY, Yu YY, Su JC, Li X, Hu HG, 2018
- Synthesis of and Specific Antibody Generation for Glycopeptides with Arginine N-GlcNAcylation, Pan M, Li S, Li X, Shao F, Liu L, Hu HG, 2014
