Areas of Focus
- 在哺乳动物复杂的染色质环境下研究DNA复制、DNA损伤和DNA代谢
- 在时间和空间尺度上研究淋巴细胞功能的变化
- 深入挖掘抗体的发育和成熟机理,并利用合成生物学技术
Work Experience
- 2016 - 至今: 研究员,北京大学
- 2012 - 2016: 博士后,哈佛大学医学院及波士顿儿童医院
Academic Background & Achievements
- 2006 学士: 北京大学
- 2012 博士: 北京大学
Publications
- Fork coupling directs DNA replication elongation and termination, Liu Y, Zhangding Z, Liu X, Gan T, Ai C, Wu J, Liang H, Chen M, Guo Y, Lu R, Jiang Y, Ji X, Gao N, Kong DC, Li Q & Hu J, 2024
- Cohesin maintains replication timing to suppress DNA damage on cancer genes, Wu J, Liu Y, Zhangding Z, Liu X, Ai C, Gan T, Liang H, Guo Y, Chen M, Liu Y, Yin J, Zhang W & Hu J, 2023
- Safeguarding genome integrity during gene-editing therapy of age-related macular degeneration, Yin J, Fang K, Gao Y, Ou L, Yuan S, Xin C, Wu W, Wu W-W, Hong J, Yang H & Hu J, 2022
- Engineering of efficiency enhanced Cas9 and base editors with improved gene therapy efficacies, Yin S, Zhang M, Liu Y, Sun X, Chen X, Yang L, Huo Y, Yang J, Zhang X, Han H, Zhang J, Li G, Xiao M, Guan Y, Liu M, Hu J, Wang L & Li D, 2022
- CRISPR/Cas9-induced structural variations expand in T lymphocytes in vivo, Wu J, Zou Ziye, Liu Y, Liu X, Zhangding Z, Xu M & Hu J, 2022
- Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption, Xin C, Yin J, Yuan S, Ou L, Liu M, Zhang W & Hu J, 2022
- Long-term correction of haemophilia B through CRISPR/Cas9 induced homology-independent targeted integration, Chen X, Niu X, Liu Y, Zheng R, Yang L, Lu J, Yin S, Wei Y, Pan J, Sayed A, Ma X, Liu M, Jing F, Liu M, Hu J, Wang L & Li D
Awards
- 奖教金杰出青年奖, 2022
- 教学优秀奖, 2021
- 郑昌学奖教金, 2021
- 求是杰出青年学者, 2018
- 绿叶生物医药杰出青年, 2018
- 拜耳学者, 2018
- 億方学者, 2017
- 哈佛华人生命科学研究奖, 2016
- 美国癌症研究中心博士后奖学金, 2014
- 吴瑞奖学金, 2012
- 北京市优秀毕业生, 2012
- 北京大学优秀毕业生, 2012
- 北京大学优秀毕业论文奖, 2012