Professor | 刘鑫 | 数字化转型顾问

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Name	刘鑫
Contact Information	lx@whu.edu.cn
Language ability	英语, 汉语
Province	湖北省

Upload Avatar (500 x 500)

Name

刘鑫

Contact Information

lx@whu.edu.cn

Language ability

英语, 汉语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	1994—1998 武汉大学，生命科学学院，本科 2000—2005 武汉大学，生命科学学院微生物专业，硕博连读 2005—2008 美国哈佛大学医学院/贝斯以色列医院，博士后
Work Experience	2009—2016 武汉大学药学院，副教授 2016—至今，教授，博士生导师
Awards	2012年黄鹤英才 2014年武汉大学药学院青年教师讲课比赛二等奖 2015年湖北省优秀学士论文指导老师，武汉大学先进女职工 2016年武汉大学医学部突出贡献奖 2017年武汉大学教学成果奖二等奖（参与） 2018年湖北省高等学校教学成果奖三等奖（参与）

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

1994—1998 武汉大学，生命科学学院，本科
2000—2005 武汉大学，生命科学学院微生物专业，硕博连读
2005—2008 美国哈佛大学医学院/贝斯以色列医院，博士后

Work Experience

2009—2016 武汉大学药学院，副教授
2016—至今，教授，博士生导师

Awards

2012年黄鹤英才
2014年武汉大学药学院青年教师讲课比赛二等奖
2015年湖北省优秀学士论文指导老师，武汉大学先进女职工
2016年武汉大学医学部突出贡献奖
2017年武汉大学教学成果奖二等奖（参与）
2018年湖北省高等学校教学成果奖三等奖（参与）

Areas of Focus	肿瘤的血管生成调控机制抗肿瘤药物及相关机制研究抗病毒药物及相关机制研究
Publications	A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis, Hou S, Niu G, Liu X, Bourbon PM, Zhang D, Cui P, Zhao K, Zhao D, Zeng H, 2021 Feeding Recombinant E. coli with GSTmBmKTX Fusion Protein Increases the Fecundity and Lifespan of Caenorhabditis elegans, Xu J, Jiang Y, Wan L, Wang Q, Huang Z, Liu Y, Wu Y, Chen Z, Liu X, 2017 rBmαTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis Elegans, Chen L, Zhang J, Xu J, Wan L, Teng K, Xiang J, Zhang R, Huang Z, Liu Y, Li W, Liu X, 2016 Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer, Teng K, Deng C, Xu J, Men Q, Lei T, Di D, Liu T, Li W, Liu X, 2016 Extracts of Tsai Tai (Brassica chinensis): enhanced antioxidant activity and anti-aging effects both in vitro and in Caenorhabditis elegans, Chen J, Zhang J, Xiang Y, Xiang L, Liu Y, He X, Zhou X, Liu X, Huang Z, 2016 Preclinical Evaluation of an Epidermal Growth Factor Receptor-Targeted Doxorubicin-Peptide Conjugate: Toxicity, Biodistribution, and Efficacy in Mice, Yang F, Ai W, Jiang F, Liu X, Huang Z, Ai S, 2016 Characterization of the transcriptional activation domains of human TEF3-1 (transcription enhancer factor 3 isoform 1), Qiao C, Jiang Y, Deng C, Huang Z, Teng K, Chen L, Liu X, 2015 Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells, Liu T, Men Q, Wu G, Yu C, Huang Z, Liu X, Li W, 2015 Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species, Wang H, Liu T, Li L, Wang Q, Yu C, Liu X, Li W, 2015 Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo, Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X, 2015 Requirement of the nuclear localization of transcription enhancer factor 3 for proliferation, migration, tube formation, and angiogenesis induced by vascular endothelial growth factor, Liu X, Zhao D, James L, Li J, Zeng H, 2011 Transcription Enhancer Factor 3 (TEF3) Mediates the Expression of Down Syndrome Candidate Region 1 Isoform 1 (DSCR1-1L) in Endothelial Cells, Liu X, Zhao D, Qin L, Li J, Zeng H, 2008

Areas of Focus

肿瘤的血管生成调控机制
抗肿瘤药物及相关机制研究
抗病毒药物及相关机制研究

Publications

A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis, Hou S, Niu G, Liu X, Bourbon PM, Zhang D, Cui P, Zhao K, Zhao D, Zeng H, 2021
Feeding Recombinant E. coli with GSTmBmKTX Fusion Protein Increases the Fecundity and Lifespan of Caenorhabditis elegans, Xu J, Jiang Y, Wan L, Wang Q, Huang Z, Liu Y, Wu Y, Chen Z, Liu X, 2017
rBmαTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis Elegans, Chen L, Zhang J, Xu J, Wan L, Teng K, Xiang J, Zhang R, Huang Z, Liu Y, Li W, Liu X, 2016
Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer, Teng K, Deng C, Xu J, Men Q, Lei T, Di D, Liu T, Li W, Liu X, 2016
Extracts of Tsai Tai (Brassica chinensis): enhanced antioxidant activity and anti-aging effects both in vitro and in Caenorhabditis elegans, Chen J, Zhang J, Xiang Y, Xiang L, Liu Y, He X, Zhou X, Liu X, Huang Z, 2016
Preclinical Evaluation of an Epidermal Growth Factor Receptor-Targeted Doxorubicin-Peptide Conjugate: Toxicity, Biodistribution, and Efficacy in Mice, Yang F, Ai W, Jiang F, Liu X, Huang Z, Ai S, 2016
Characterization of the transcriptional activation domains of human TEF3-1 (transcription enhancer factor 3 isoform 1), Qiao C, Jiang Y, Deng C, Huang Z, Teng K, Chen L, Liu X, 2015
Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells, Liu T, Men Q, Wu G, Yu C, Huang Z, Liu X, Li W, 2015
Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species, Wang H, Liu T, Li L, Wang Q, Yu C, Liu X, Li W, 2015
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo, Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X, 2015
Requirement of the nuclear localization of transcription enhancer factor 3 for proliferation, migration, tube formation, and angiogenesis induced by vascular endothelial growth factor, Liu X, Zhao D, James L, Li J, Zeng H, 2011
Transcription Enhancer Factor 3 (TEF3) Mediates the Expression of Down Syndrome Candidate Region 1 Isoform 1 (DSCR1-1L) in Endothelial Cells, Liu X, Zhao D, Qin L, Li J, Zeng H, 2008

血管生成肿瘤血管药物开发机制抗肿瘤治疗药理学分子生物学临床研究

董金堂 - 南方科技大学

李婉秋 - 南方科技大学

任欢 - 南方科技大学

Area of Focus
免疫学 | 肿瘤 | 临床 | 分子 | 生物医学 | 生物信息学 | 医学 | 生物物理 | 建模 | 治疗

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