Areas of Focus
- 生物钟与糖脂代谢互作的分子机制
Work Experience
- 2004.04—2005.08 - 美国加州大学河滨分校 - 博士后
- 2005.09—2010.01 - 美国索科尔生物研究所 - 博士后
- 2010.02—2017.08 - 中科院上海生科院营养科学研究所 - 研究员
- 2017.09—至今 - 复旦大学基础医学院 - 研究员
Academic Background & Achievements
- 1992.09—1997.07 复旦大学遗传学专业本科生
- 1998.09—2004.03 美国加州大学河滨分校生物医学专业博士研究生
Publications
- A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex., Chen Y, Wang J, Wang Y, Wang P, Zhou Z, Wu R, Xu Q, You H, Liu Y, Wang L, Zhou L, Wu Y, Hu L, Liu H, Liu Y*., 2022
- The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex., Wu R., Dang F., Li P., Wang P., Xu Q., Liu Z., Li Y., Wu Y., Chen Y., Liu Y*., 2019
- Fasting and Feeding Signals Control the Oscillatory Expression of Angptl8 to Modulate Lipid Metabolism., Dang F., Wu R., Wang P., Wu Y., Azam S., Liu Y*., 2016
- Insulin post-transcriptionally modulates Bmal1 protein to affect the hepatic circadian clock., Dang, F., Sun, X., Ma, X., Wu, R., Zhang, D., Chen, Y., Xu, Q., Wu, Y., Liu Y*., 2016
- RBP4 functions as a hepatokine in the regulation of glucose metabolism by the circadian clock in mice., Ma X, Zhou Z, Chen Y, Wu Y, Liu Y*., 2016
- Glucagon-CREB/CRTC2 Signaling Cascade Regulates Hepatic BMAL1 Protein., Sun, X., Dang, F., Zhang, D., Yuan, Y., Zhang, C., Wu, Y., Wang, Y., Liu, Y*., 2015
- Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis., Zhang, E.E*., Liu, Y*., Dentin, R., Pongsawakul, P.Y., Liu, A.C., Hirota, T., Nusinow, D.A., Sun, X., Landais, S., Kodama, Y., Brenner, D.A., Montminy, M., Kay, S.A., 2010
- Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity., Wang, Y., Inoue, H., Ravnskjaer, K., Viste, K., Miller, N., Liu, Y*., Hedrick, S., Vera, L., Montminy, M., 2010
- A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange., Liu, Y*., Dentin, R.*, Chen, D., Hedrick, S., Ravnskjaer, K., Schenk, S., Milne, J., Meyers, D.J., Cole, P., Yates, J.R. 3rd., Olefsky, J., Guarente, L., Montminy, M., 2008
- Insulin Modulates Gluconeogenesis via Inhibition of the Coactivator TORC2., Dentin, R.*, Liu, Y*., Koo, S., Hedrick, S., Vargas, T., Heredia, J., Yates, J.R. 3rd., Montminy, M., 2007
Awards
- 2013: 国家自然科学基金优青项目
- 2010: 上海市浦江人才