Professor | 龙钢 | 数字化转型顾问

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Name	龙钢
Language ability	中文, 英文, 德文
Province	上海

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Name

龙钢

Language ability

中文, 英文, 德文

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	1995.09—1999.07 生物工程专业本科生: 南昌大学 1999.09—2002.07 病毒学专业硕士研究生: 中国科学院武汉病毒研究所 2002.09—2007.03 病毒学专业博士研究生: 荷兰瓦格宁根大学
Work Experience	2002.07—2007.07 - 中国科学院武汉病毒研究所 - 助理研究员 2007.07—2012.12 - 德国海德堡大学医学院 - 博士后 2013.01—2022.02 - 中国科学院上海巴斯德研究所 - 研究员，课题组长 2022.03—至今 - 复旦大学基础医学院病原生物系 - 研究员，课题组长
Awards	欧盟玛丽居里奖学金 (2007)

University/Lab Affiliation and Title

复旦大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

1995.09—1999.07 生物工程专业本科生: 南昌大学
1999.09—2002.07 病毒学专业硕士研究生: 中国科学院武汉病毒研究所
2002.09—2007.03 病毒学专业博士研究生: 荷兰瓦格宁根大学

Work Experience

2002.07—2007.07 - 中国科学院武汉病毒研究所 - 助理研究员
2007.07—2012.12 - 德国海德堡大学医学院 - 博士后
2013.01—2022.02 - 中国科学院上海巴斯德研究所 - 研究员，课题组长
2022.03—至今 - 复旦大学基础医学院病原生物系 - 研究员，课题组长

Awards

欧盟玛丽居里奖学金 (2007)

Areas of Focus	肝炎、虫媒等医学病毒的感染和致病机制及病毒感染活细胞示踪体系研发胞外囊泡生物发生和物质分选机制
Publications	An intein-split transactivator for intersectional neural imaging and optogenetic manipulation, Chen H, Zhang X, Yang R, Wang G, Long G, Xu C, 2022 Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles, Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G, 2020 Syntenin regulates hepatitis C virus sensitivity to neutralizing antibody by promoting E2 secretion through exosomes, Deng L, Jiang W, Wang X, Merz A, Hiet MS, Chen Y, Pan X, Jiu Y, Yang Y, Yu B, He Y, Tu Z, Niu J, Bartenschlager R, Long G, 2019 Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication, Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL, 2019 Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone, Zhao F, Xu Y, Lavillette D, Zhong J, Zou G, Long G, 2018 Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system, Jiang W, Muhammad F, Ma P, Liu X, Long G, 2018 Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model, Levander S, Holmström F, Frelin L, Ahlén G, Rupp D, Long G, Bartenschlager R, Sällberg M, 2018 Visualizing the Essential Role of Complete Virion Assembly Machinery in Efficient Hepatitis C Virus Cell-to-Cell Transmission by a Viral Infection-Activated Split-Intein-Mediated Reporter System, Zhao F, Zhao T, Deng L, Lv D, Zhang X, Pan X, Xu J, Long G, 2017 Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection, Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G, 2016 Mouse hepatic cells support assembly of infectious hepatitis C virus particles, Long G, Hiet MS, Windisch MP, Lee JY, Lohmann V, Bartenschlager R, 2011

Areas of Focus

肝炎、虫媒等医学病毒的感染和致病机制及病毒感染活细胞示踪体系研发
胞外囊泡生物发生和物质分选机制

Publications

An intein-split transactivator for intersectional neural imaging and optogenetic manipulation, Chen H, Zhang X, Yang R, Wang G, Long G, Xu C, 2022
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles, Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G, 2020
Syntenin regulates hepatitis C virus sensitivity to neutralizing antibody by promoting E2 secretion through exosomes, Deng L, Jiang W, Wang X, Merz A, Hiet MS, Chen Y, Pan X, Jiu Y, Yang Y, Yu B, He Y, Tu Z, Niu J, Bartenschlager R, Long G, 2019
Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication, Bian WX, Xie Y, Wang XN, Xu GH, Fu BS, Li S, Long G, Zhou X, Zhang XL, 2019
Negligible contribution of M2634V substitution to ZIKV pathogenesis in AG6 mice revealed by a bacterial promoter activity reduced infectious clone, Zhao F, Xu Y, Lavillette D, Zhong J, Zou G, Long G, 2018
Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system, Jiang W, Muhammad F, Ma P, Liu X, Long G, 2018
Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model, Levander S, Holmström F, Frelin L, Ahlén G, Rupp D, Long G, Bartenschlager R, Sällberg M, 2018
Visualizing the Essential Role of Complete Virion Assembly Machinery in Efficient Hepatitis C Virus Cell-to-Cell Transmission by a Viral Infection-Activated Split-Intein-Mediated Reporter System, Zhao F, Zhao T, Deng L, Lv D, Zhang X, Pan X, Xu J, Long G, 2017
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection, Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G, 2016
Mouse hepatic cells support assembly of infectious hepatitis C virus particles, Long G, Hiet MS, Windisch MP, Lee JY, Lohmann V, Bartenschlager R, 2011

肝炎虫媒病毒感染机制致病机制活细胞示踪胞外囊泡生物发生物质分选病毒感染医学病毒

熊海蓉 - 武汉大学

张荣 - 复旦大学

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