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徐莺莺
Basic Medical Sciences
复旦大学
上海
Language: 中文, 英语
细胞极性
癌症
肿瘤
代谢
生物化学
分子生物学
糖基转移酶
细胞行为
凋亡
乳腺癌
Areas of Focus
- 细胞极性与肿瘤
- 肿瘤代谢
Work Experience
- 2000-2005 - 复旦大学，上海医学院生物化学与分子生物学系 - 助教
- 2006-2015 - 复旦大学，上海医学院生物化学与分子生物学系 - 讲师
- 2016-至今 - 复旦大学，上海医学院生物化学与分子生物学系 - 副教授
Academic Background & Achievements
- 1996.09-2000.07 学士学位，药物化学专业：复旦大学
- 2001.09-2005.07 硕士学位，生物化学与分子生物学系：复旦大学
- 2006.09-2010.07 博士学位，生物化学与分子生物学系：复旦大学
Publications
- A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients, Biyun Wang, Yannan Zhao, Yi Li, Yingying Xu, Yun Chen, Qiuyu Jiang, Dingjin Yao, Li Zhang, Xichun Hu, Chaowei Fu, Si Zhang, She Chen, 2022
- Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis, Wang S, Cai J, Zhang S, Dong M, Zhang L, Xu Y, Shen B, Chen S, 2021
- Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest, Yannan Zhao, Huitong Peng, Limiao Liang, Yi Li, Xichun Hu, Biyun Wang, Yingying Xu, She Chen, 2022
- CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation, Zhao Guang-Xi, Xu Ying-Ying, Weng Shu-Qiang, Zhang Si, Chen Ying, Shen Xi-Zhong, Dong Ling, Chen She, 2019
- Acetylation targets HSD17B4 for degradation via the CMA pathway in response to estrone, Zhang Y, Xu YY, Yao CB, Li JT, Zhao XN, Yang HB, Zhang M, Yin M, Chen J, Lei QY, 2017
- Acetylation of MAT IIa represses tumour cell growth and is decreased in human hepatocellular cancer, Yang HB, Xu YY, Zhao XN, Zou SW, Zhang Y, Zhang M, Li JT, Ren F, Wang LY, Lei QY, 2015
- Cullin 3 targets methionine adenosyltransferase IIα for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation, Wang J, Zhu ZH, Yang HB, Zhang Y, Zhao XN, Zhang M, Liu YB, Xu YY, Lei QY, 2016
- All-trans-retinoic acid intensifies endoplasmic reticulum stress in N-acetylglucosaminyltransferase V repressed human hepatocarcinoma cells by perturbing homocysteine metabolism, Xu YY, Guan DY, Yang M, Wang H, Shen ZH, 2010
- Apoptosis induced by all-trans retinoic acid in N-acetylglucosaminyltransferase V repressed human hepatocarcinoma cells is mediated through endoplasmic reticulum stress, Xu YY, Lu Y, Fan KY, Shen ZH, 2007
- Blocking of N-acetylglucosaminyltransferase V induces cellular endoplasmic reticulum stress in human hepatocarcinoma 7721 cells, Fang H, Huang W, Xu YY, Shen ZH, Wu CQ, Qiao SY, Xu Y, Yu L, Chen HL, 2006
Awards
- 上海市科学技术进步奖 (2007): 糖基转移酶对细胞生物学行为的调控，三等奖
