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刘洪瑞
Pharmaceutical Sciences
复旦大学
上海
Language: 中文, 英语
心血管
药理学
心脏
血管
药物
癌症
肿瘤
化疗
凋亡
细胞周期
Areas of Focus
- 心血管药理学
- 肿瘤药理学
Work Experience
- 2007年至今 - 复旦大学 - 讲师、副教授
Academic Background & Achievements
- 1991年 - 临床医学学士学位: 第二军医大学
- 2005年 - 药理学博士学位: 中国医科大学
- 参编国家级规划教材：《临床药理学》第3版和《药物毒理学》第2版
- 主持重大新药创制平台和中药现代化子项目
- 申请发明专利3项
- 发表论文20余篇
Publications
- Cochinchina Momordica Seed Extract Induces Apoptosis and Cell Cycle Arrest in Human Gastric Cancer Cells Via PARP and p53 Signal Pathways, Liu HR, Meng LY, Lin ZY, et al., 2012
- Antitumor agents 292. Design, synthesis and pharmacological study of S- and O-substituted 7-mercapto- or hydroxy-coumarins and chromones as potent cytotoxic agents, Chen Y*, Liu HR*, Liu HS, et al., 2012
- Cochinchina momordica seed extract induces G2/M arrest and apoptosis in human breast cancer MDA-MB-231 cells by modulating the PI3K/Akt pathway, Meng LY*, Liu HR*, Shen Y, et al., 2011
- Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies, Zheng Y*, Liu H*, Ma G, et al., 2011
- BRCA2 Dysfunction Promotes Malignant Transformation of Pancreatic Intraepithelial Neoplasia, Wang Q*, Liu H*, Liu T, et al., 2013
- Synthesis and evaluation of tetrahydro βcarboline derivatives as anticancer agents, Hongrui Liu*, Guangzhi Bao*, Suna Yang, et al., 2012
Awards
- 上海市首届执业药师继续教育金牌教师
- 上海药学科技奖二等奖
