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谭文福
Pharmaceutical Sciences
复旦大学
上海
Language: 中文, 英语
抗肿瘤
药物活性
体外
体内
评价
分子靶向
药物研发
药理学
癌症
治疗
Areas of Focus
- 抗肿瘤药物体外、体内活性评价
- 分子靶向抗肿瘤药物的研发
Work Experience
- 2017/12 - 至今 - 复旦大学 - 研究员
- 2009/7 - 2017/12 - 复旦大学 - 副研究员
- 2008/4 - 2009/4 - 中国科学院上海生化细胞所 - 副研究员
- 2003/10 - 2008/4 - 美国国家卫生研究院，NIDCR - 访问学者
- 2001/10 - 2003/10 - 中国科学院上海药物研究所 - 博士后
Academic Background & Achievements
- 1998/9 - 2001/6 临床医学博士: 同济医科大学
- 1995/9 - 1998/6 临床医学硕士: 衡阳医学院
- 1990/9 - 1995/6 中医临床学学士: 湖南中医学院
Publications
- Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G#, Huang W#, Wang J#, Liu X, Yang J, Zhang Y, Geng Y, Tan W*, Zhang A*, 2017
- Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand, Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, Hanson MA, Cherezov V, Stevens RC, Tan W*, Tao H*, Xu F*, 2017
- Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists, Liu G#, Xue D#, Yang J#, Wang J#, Liu X, Huang W, Li J, Long YQ*, Tan W*, Zhang A*, 2016
- Twist1 and Snail link Hedgehog signaling to tumor-initiating cell-like properties and acquired chemoresistance independently of ABC transporters, Kong Y#, Peng Y#, Liu Y#, Xin H, Zhan X, Tan W*, 2015
- GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli, Zhan X, Wang J, Liu Y, Peng Y, Tan W*, 2014
