Professor | 谭文福 | 数字化转型顾问

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Name	谭文福
Contact Information	{'en': 'Email: wftan@@fudan.edu.cn\\nPhone: 021-51980039', 'zh': '电子邮件：wftan@@fudan.edu.cn\\n电话：021-51980039', 'de': 'E-Mail: wftan@@fudan.edu.cn\\nTelefon: 021-51980039'}
Language ability	中文, 英语
Province	上海

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Name

谭文福

Contact Information

{'en': 'Email: wftan@@fudan.edu.cn\\nPhone: 021-51980039', 'zh': '电子邮件：wftan@@fudan.edu.cn\\n电话：021-51980039', 'de': 'E-Mail: wftan@@fudan.edu.cn\\nTelefon: 021-51980039'}

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1998/9 - 2001/6 临床医学博士: 同济医科大学 1995/9 - 1998/6 临床医学硕士: 衡阳医学院 1990/9 - 1995/6 中医临床学学士: 湖南中医学院
Work Experience	2017/12 - 至今 - 复旦大学 - 研究员 2009/7 - 2017/12 - 复旦大学 - 副研究员 2008/4 - 2009/4 - 中国科学院上海生化细胞所 - 副研究员 2003/10 - 2008/4 - 美国国家卫生研究院，NIDCR - 访问学者 2001/10 - 2003/10 - 中国科学院上海药物研究所 - 博士后

University/Lab Affiliation and Title

复旦大学

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1998/9 - 2001/6 临床医学博士: 同济医科大学
1995/9 - 1998/6 临床医学硕士: 衡阳医学院
1990/9 - 1995/6 中医临床学学士: 湖南中医学院

Work Experience

2017/12 - 至今 - 复旦大学 - 研究员
2009/7 - 2017/12 - 复旦大学 - 副研究员
2008/4 - 2009/4 - 中国科学院上海生化细胞所 - 副研究员
2003/10 - 2008/4 - 美国国家卫生研究院，NIDCR - 访问学者
2001/10 - 2003/10 - 中国科学院上海药物研究所 - 博士后

Areas of Focus	抗肿瘤药物体外、体内活性评价分子靶向抗肿瘤药物的研发
Publications	Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G#, Huang W#, Wang J#, Liu X, Yang J, Zhang Y, Geng Y, Tan W, Zhang A, 2017 Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand, Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, Hanson MA, Cherezov V, Stevens RC, Tan W, Tao H, Xu F, 2017 Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists, Liu G#, Xue D#, Yang J#, Wang J#, Liu X, Huang W, Li J, Long YQ, Tan W, Zhang A, 2016 Twist1 and Snail link Hedgehog signaling to tumor-initiating cell-like properties and acquired chemoresistance independently of ABC transporters, Kong Y#, Peng Y#, Liu Y#, Xin H, Zhan X, Tan W, 2015 GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli, Zhan X, Wang J, Liu Y, Peng Y, Tan W, 2014

Areas of Focus

抗肿瘤药物体外、体内活性评价
分子靶向抗肿瘤药物的研发

Publications

Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription, Liu G#, Huang W#, Wang J#, Liu X, Yang J, Zhang Y, Geng Y, Tan W*, Zhang A*, 2017
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand, Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, Hanson MA, Cherezov V, Stevens RC, Tan W*, Tao H*, Xu F*, 2017
Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists, Liu G#, Xue D#, Yang J#, Wang J#, Liu X, Huang W, Li J, Long YQ*, Tan W*, Zhang A*, 2016
Twist1 and Snail link Hedgehog signaling to tumor-initiating cell-like properties and acquired chemoresistance independently of ABC transporters, Kong Y#, Peng Y#, Liu Y#, Xin H, Zhan X, Tan W*, 2015
GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli, Zhan X, Wang J, Liu Y, Peng Y, Tan W*, 2014

抗肿瘤药物活性体外体内评价分子靶向药物研发药理学癌症治疗

张雪梅 - 复旦大学

Area of Focus
代谢 | 药理学 | 离子通道 | 转运体 | 信号调控 | 体内 | 体外 | 药理活性 | 评价 | 研究

李英霞 - 复旦大学

Area of Focus
药物设计 | 优化 | 抗肿瘤 | 代谢调节 | 小分子药物 | 天然产物 | 成药性 | 基于结构 | 药理学 | 化学

赵伟利 - 复旦大学

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