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张伟
zhangw416@fudan.edu.cn
中文, 英文
上海
复旦大学
Pharmaceutical Sciences
  • 2005.09 – 2008.06 博士: 中国海洋大学医药学院
  • 2002.09 – 2005.07 硕士: 中国海洋大学医药学院
  • 1998.09 – 2002.07 本科: 中国海洋大学化学化工学院
  • 2015.12 – 至今 - 复旦大学药学院 - 副教授
  • 2009.11 – 2015.11 - 复旦大学药学院 - 讲师
  • 2012.01 – 2013.01 - 佛罗里达大学药学院 - 访问学者
  • 2008.07 – 2009.10 - 中国海洋大学医药学院 - 讲师
  • 2014.05: 复旦大学药学院青年教师讲课比赛一等奖
  • 2014.11: 第四届全国高等医学院校青年教师教学基本功比赛三等奖
  • 2015.01: 复旦大学第一三共制药奖教金
基于活性天然产物的药物研究
药物优势骨架的高效构建
  • One-pot syntheses of α,α-dibromoacetophenones from aromatic alkenes with 1,3-dibromo-5,5-dimethylhydantoin, Wu Ping, Xu Senhan, Xu Hao, Hu Haiyan, Zhang Wei, 2017
  • Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors, Xu Hao, Bao Keting, Tang Shuai, Ai Jing, Hu Haiyan, Zhang Wei, 2017
  • Total synthesis and biological evaluation of apratoxin E and its C30 epimer: Configurational reassignment of the natural product, Wu Ping, Cai Weijing, Chen Qi-Yin, Xu Senhan, Yin Ruwen, Li Yingxia, Zhang Wei, Luesch Hendrik, 2016
  • 1,3-Dibromo-5,5-dimethylhydantoin (DBH) mediated one-pot syntheses of α-bromo/amino ketones from alkenes in water, Xu Senhan, Wu Ping, Zhang Wei, 2016
  • Novel azetidine-containing TZT-1027 analogues as antitumor agents, Yan Qi, Wang Yujie, Zhang Wei, Li Yingxia, 2016
  • An efficient method for the production of terminal alkynes from 1,1-dibromo-1-alkenes and its application in the total synthesis of natural product dihydroxerulin, Liu Shihui, Chen Xiaobei, Hu Yanwei, Yuan Laiqi, Chen Shaohua, Wu Ping, Wang Wei, Zhang Shilei, Zhang Wei, 2015
  • Design, synthesis and biological evaluation of tasiamide B derivatives as BACE1 inhibitors, Liu Jian, Chen Wuyan, Xu Yechun, Ren Sumei, Zhang Wei, Li Yingxia, 2015
  • Design, synthesis and biological evaluation of tasiamide analogues as tumor inhibitors, Zhang Wei, Sun Tiantian, Ma Zhenhua, Li Yingxia, 2014
  • Discovery of novel type II c-Met inhibitors based on BMS-777607, Zhang Wei, Ai Jing, Shi Dakuo, Peng Xia, Ji Yinchun, Liu Jian, Geng Meiyu, Yingxia Li, 2014
  • Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteases, Liu Yanxia, Zhang Wei, Li Li, Salvador Lilibeth A., Chen Tiantian, Chen Wuyan, Felsenstein Kevin M., Ladd Thomas B., Price Ashleigh R., Golde Todd E., He Jianhua, Xu Yechun, Li Yingxia, Luesch Hendrik, 2012
天然产物 药物研究 活性化合物 药理学 生物化学 药物设计 药物化学 生物活性分子 治疗学 药品

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