加速：基因组学研究 - 威康信托桑格研究所依靠 DDN® 的可扩展高性能存储来减轻全球健康负担
公司规模
Large Corporate
地区
- Europe
国家
- United Kingdom
产品
- DDN SFA® high-performance storage engine
- EXAScaler™ Lustre® fi le system appliance
- iRODS
技术栈
- High-performance computing
- Scalable storage architectures
- Data management systems
实施规模
- Enterprise-wide Deployment
影响指标
- Productivity Improvements
- Innovation Output
技术
- 基础设施即服务 (IaaS) - 云存储服务
适用行业
- 医疗保健和医院
- 生命科学
适用功能
- 产品研发
- 质量保证
用例
- 预测性维护
服务
- 云规划/设计/实施服务
- 数据科学服务
关于客户
威康信托桑格研究所是一家由慈善组织资助的位于英国的基因组研究中心，在研究遗传学和基因组学对全球健康的影响方面处于世界领先地位。自 1993 年成立以来，桑格研究所对基因组及其在生物学中的作用有了新的认识，同时取得了基因组研究的一些最重要进展。该组织在人类基因组计划 (HGP) 中发挥了关键作用，这是一项国际合作研究计划，其目标是全面绘制和了解人类所有基因。桑格研究所还领导了第一条人类染色体的研究，并最终贡献了三分之一的人类基因组，帮助该计划在 2003 年 4 月之前实现目标。多年来，该研究所的工作还做出了其他重大贡献，帮助减轻了全球健康负担，为新的诊断和治疗方法奠定了基础。
挑战
基因组研究中心 Wellcome Trust Sanger 研究所在管理因测序技术重大进步而激增的数据量和计算分析方面面临挑战。该研究所的研究团队多元化，包括全球 2,000 多名科学家，需要具有大规模、高吞吐量性能的强大 IT 基础设施。数据增长不可预测，因此很难充分扩展存储，否则研究所现有的 10-GigE 网络基础设施将不堪重负，或超出空间受限的数据中心每地砖 1PB 的规定。该研究所出现了一个典型的“大数据”问题，每当测序技术的新进展以前所未有的速度产生更多测序数据时，这个问题就会进一步加剧。
解决方案
Sanger 研究所选择 DDN 的 SFA® 高性能存储引擎、EXAScaler™ Lustre® 文件系统设备和 iRODS 来解决其数据管理挑战。之所以选择 DDN 的解决方案，是因为其卓越的 Lustre 解决方案、在高性能计算和可扩展存储架构各个方面的端到端技术专长，以及提供前所未有的吞吐量和可扩展性的能力。该研究所测试了硬件和服务器，在平台上运行了代码，并结识了可能在未来为他们提供支持的 DDN 团队。在安装了最初的 SFA10K 存储平台（为运行 Lustre 的 EXAScalerTM 并行文件系统提供支持）后，该研究所可以轻松跟上不断发展的计算和分析需求。该团队还利用 DDN 的技术进步，将初始性能从 3GB/s 提高一倍至 6GB/s，然后增长到 10GB/s，然后大幅增加到 20GB/s。
运营影响
数量效益
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