Professor | 蒋颖 | 数字化转型顾问

Name	蒋颖
Contact Information	ying_jiang@tongji.edu.cn
Language ability	英语, 汉语
Province	上海

Name

蒋颖

Contact Information

ying_jiang@tongji.edu.cn

Language ability

英语, 汉语

Province

上海

University/Lab Affiliation and Title	同济大学
Faculty	Life Sciences
Academic Background & Achievements	2004年 - 学士学位：南京大学生命科学学院 2013年 - 博士学位：美国罗彻斯特大学生物系在PNAS、Nucleic Acids Res.、Oncogene、JBC等重要学术期刊发表通讯、共同通讯、第一及共同第一作者论文10余篇
Work Experience	2013年至今：同济大学生命科学与技术学院 - 助理研究员、副研究员、副教授

University/Lab Affiliation and Title

同济大学

Faculty

Life Sciences

Academic Background & Achievements

2004年 - 学士学位：南京大学生命科学学院
2013年 - 博士学位：美国罗彻斯特大学生物系
在PNAS、Nucleic Acids Res.、Oncogene、JBC等重要学术期刊发表通讯、共同通讯、第一及共同第一作者论文10余篇

Work Experience

2013年至今：同济大学生命科学与技术学院 - 助理研究员、副研究员、副教授

Areas of Focus	乳腺癌及妇科肿瘤相关DNA修复调控机制靶向DNA修复预防及治疗乳腺癌和妇科肿瘤的新方法
Publications	Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PKcs inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y, Sun FL, Mao Z, 2020 A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, SuT, ShiJ, Jiang C, Tian X, SeluanovA, HuangJ, WanX, Jiang Y, Gorbunova V,Mao Z, 2019 The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression, Zhang F, Tang H, Jiang Y,Mao Z, 2017 Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy, Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y,Mao Z, 2018 POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions, Yu Y, Tang R, Ren Q, Gao B, Sheng Z, Zhang J, Zheng X, Jiang Y, Li Lan,Mao Z, 2017 Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer, Hu Z, Cai B, Wang M, Wen X, Geng A, Hu X, Xue R, Mao Z, Jiang Y, Wan X, 2020 Triptolide impairs genome integrity by directly blocking the enzymatic activity of DNA-PKcs in human cells, Cai B, Hu Z, Tang H, Hu Z, Mao Z, Liu B, Xu X, Jiang Y, Wan X, 2020 Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells, Zhang L, Zhang F, Zhang W, Chen L, Gao N, Men Y, Xu X, Jiang Y, 2015 Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells, Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, 2013 DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells, Mao Z#, Jiang Y#, Liu X, Seluanov A, Gorbunova V, 2009

Areas of Focus

乳腺癌及妇科肿瘤相关DNA修复调控机制
靶向DNA修复预防及治疗乳腺癌和妇科肿瘤的新方法

Publications

Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PKcs inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y*, Sun FL*, Mao Z*, 2020
A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, SuT, ShiJ, Jiang C, Tian X, SeluanovA, HuangJ, WanX, Jiang Y*, Gorbunova V*,Mao Z*, 2019
The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression, Zhang F, Tang H, Jiang Y*,Mao Z*, 2017
Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy, Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y*,Mao Z*, 2018
POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions, Yu Y, Tang R, Ren Q, Gao B, Sheng Z, Zhang J, Zheng X, Jiang Y*, Li Lan*,Mao Z*, 2017
Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer, Hu Z, Cai B, Wang M, Wen X, Geng A, Hu X, Xue R, Mao Z, Jiang Y*, Wan X*, 2020
Triptolide impairs genome integrity by directly blocking the enzymatic activity of DNA-PKcs in human cells, Cai B, Hu Z, Tang H, Hu Z, Mao Z, Liu B, Xu X, Jiang Y*, Wan X*, 2020
Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells, Zhang L, Zhang F, Zhang W, Chen L, Gao N, Men Y, Xu X, Jiang Y*, 2015
Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells, Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, 2013
DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells, Mao Z#, Jiang Y#, Liu X, Seluanov A, Gorbunova V, 2009

乳腺癌妇科肿瘤 Dna修复调控机制靶向治疗预防治疗方法研究细胞模型动物模型

毛志勇 - 同济大学

张家民 - 同济大学

曾赵军 - 中南大学

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