Areas of Focus
- 细胞衰老的分子机制
- 炎性衰老在神经系统疾病中的作用与机制
- 老年性神经退行性疾病的缓解与治疗
Work Experience
- 2009-2018年 - 包括新加坡科技研究局、美国霍华德休斯医学研究所等科研院所：博士后、科研专员
- 2020年至今 - 同济大学附属第一妇婴保健院：副研究员
Academic Background & Achievements
- 2002年 - 学士学位：南京大学生命科学学院
- 2005年 - 硕士学位：南京大学生命科学学院
- 2009年 - 博士学位：新加坡南洋理工大学
- 2020年入选上海市“浦江人才”计划
Publications
- A two-subpopulation model that reflects heterogeneity of large dense core vesicles in exocytosis, Qin N, Chen Z, Xue R*, 2022
- Activated or Impaired: An Overview of DNA Repair in Neurodegenerative Diseases, Qin N, Geng A, Xue R*, 2021
- The Role of Calmodulin vs. Synaptotagmin in Exocytosis, Xue R*, Meng H, Yin J, Xia J, Hu Z, Liu H*, 2021
- Doc2-mediated superpriming supports synaptic augmentation, Xue R, Ruhl DA, Briguglio JS, Figueroa AG, Pearce RA, Chapman ER*, 2018
- Different states of synaptotagmin regulate evoked versus spontaneous release, Bai H#, Xue R#, Bao H, Zhang L, Yethiraj A, Cui Q, Chapman ER*, 2016
- Structural elements that underlie Doc2 beta function during asynchronous synaptic transmission, Xue R#, Gaffaney JD#, Chapman ER*, 2015
- Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission, Liu H#, Bai H#, Xue R, Takahashi H, Edwardson JM, Chapman ER*, 2014
- Mutations that disrupt Ca2+-binding activity endow Doc2 beta with novel functional properties during synaptic transmission, Gaffaney JD#, Xue R#, Chapman ER*, 2014
- Roles of Cholesterol in Vesicle Fusion and Motion, Zhang J#, Xue R#, Ong W-Y, Chen P*, 2009
- PKC epsilon facilitates recovery of exocytosis after an exhausting stimulation, Xue R, Zhao Y, Su L, Ye F, Chen P*, 2009
- Involvement of PKC alpha in PMA-induced facilitation of exocytosis and vesicle fusion in PC12 cells, Xue R, Zhao Y, Chen P*, 2009
- Protective effects of ethyl docosahexaenoate on brain oxidative injury and edema induced by cerebral ischemic reperfusion, Xue R, Cao D, Zheng W, Sun L, Liu Z*, 2004
