Professor | 刘倩 | 数字化转型顾问

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Name

刘倩

Contact Information

liuqian1018@sjtu.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	上海交通大学
Faculty	Life Sciences
Academic Background & Achievements	2010-2011 美国加州大学洛杉矶分校，化学与生物分子工程系，交流 2007-2012 上海交通大学生命科学技术学院，微生物学，博士 2003-2007 上海交通大学生命科学技术学院，生物技术，本科主持国家自然科学基金，重点研发计划子课题
Work Experience	2020 -迄今上海交通大学生命科学技术学院，副研究员 2015-2019 上海交通大学生命科学技术学院，助理研究员 2013-2015 武汉大学药学院，博士后/助理研究员
Awards	2016年，上海市科委青年科技英才扬帆计划 2016年，上海交通大学晨星青年学者奖励计划

University/Lab Affiliation and Title

上海交通大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Awards

Areas of Focus	微生物天然产物生物合成的酶学机制及分子设计微生物核酸酶的酶学机制及基因检测开发从事微生物次级代谢产物的生物合成及定向改造
Publications	Mesophilic Argonaute-based isothermal detection of SARS-CoV-2, 刘倩, 2022 Argonaute-integrated isothermal amplification for rapid, portable, multiplex detection of SARS-CoV-2 and influenza viruses, 刘倩, 2022 Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity, 刘倩, 2022 Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations, 刘倩, 2021 Utility of B‑Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability, 刘倩, 2018 The state-of-the-art strategies of protein engineering for enzyme stabilization, 刘倩, 2018 Argonaute with stepwise endonuclease activity promotes specific and multiplex nucleic acid detection, 刘倩, 2021 Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis, 刘倩, 2019 A hyperthermophilic Argonaute from Ferroglobus placidus with specificity on guide binding pattern, 刘倩, 2021 Characterization of protein interaction surface on fatty acyl selectivity of starter condensation domain in lipopeptide biosynthesis, 刘倩, 2019

Areas of Focus

微生物天然产物生物合成的酶学机制及分子设计
微生物核酸酶的酶学机制及基因检测开发
从事微生物次级代谢产物的生物合成及定向改造

Publications

Mesophilic Argonaute-based isothermal detection of SARS-CoV-2, 刘倩, 2022
Argonaute-integrated isothermal amplification for rapid, portable, multiplex detection of SARS-CoV-2 and influenza viruses, 刘倩, 2022
Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity, 刘倩, 2022
Argonaute integrated single-tube PCR system enables supersensitive detection of rare mutations, 刘倩, 2021
Utility of B‑Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability, 刘倩, 2018
The state-of-the-art strategies of protein engineering for enzyme stabilization, 刘倩, 2018
Argonaute with stepwise endonuclease activity promotes specific and multiplex nucleic acid detection, 刘倩, 2021
Probing and Engineering the Fatty Acyl Substrate Selectivity of Starter Condensation Domains of Nonribosomal Peptide Synthetases in Lipopeptide Biosynthesis, 刘倩, 2019
A hyperthermophilic Argonaute from Ferroglobus placidus with specificity on guide binding pattern, 刘倩, 2021
Characterization of protein interaction surface on fatty acyl selectivity of starter condensation domain in lipopeptide biosynthesis, 刘倩, 2019

酶分子设计生物合成微生物天然产物核酸酶基因检测次级代谢产物代谢途径蛋白质工程

邓子新 - 上海交通大学

刘倩 - 上海交通大学

张雪洪 - 上海交通大学

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