Professor | 吴丽 | 数字化转型顾问

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Name	吴丽
Contact Information	14_wuli@tongji.edu.cn
Language ability	中文, 英语
Province	上海

Upload Avatar (500 x 500)

Name

吴丽

Contact Information

14_wuli@tongji.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	同济大学
Faculty	Life Sciences
Academic Background & Achievements	2014.07-2018.01 同济大学/中国科学院生物物理研究所生物化学与分子生物学博士 2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心生物医学硕士 2002.09-2006.06 石河子大学食品工程学院工学学士
Work Experience	2018.02-至今同济大学附属第一妇婴保健院助理研究员、副研究员 2014.07-2018.01 同济大学/中国科学院生物物理研究所博士生 2012.07-2014.06 中国科学院上海生命科学研究院助理研究员 2011.07-2012.06 上海市药明康德新药开发有限公司研究员 2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心硕士生

University/Lab Affiliation and Title

同济大学

Faculty

Life Sciences

Academic Background & Achievements

2014.07-2018.01 同济大学/中国科学院生物物理研究所生物化学与分子生物学博士
2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心生物医学硕士
2002.09-2006.06 石河子大学食品工程学院工学学士

Work Experience

2018.02-至今同济大学附属第一妇婴保健院助理研究员、副研究员
2014.07-2018.01 同济大学/中国科学院生物物理研究所博士生
2012.07-2014.06 中国科学院上海生命科学研究院助理研究员
2011.07-2012.06 上海市药明康德新药开发有限公司研究员
2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心硕士生

Areas of Focus	体细胞重编程机制研究应用多能干细胞以及临床样本进行女性生殖系统生理病理过程的体外模拟及再生医学研究
Publications	Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics, Chen T, Xu Y, Xu X, Wang J, Qiu Z, Yu Y, Jiang X, Shao W, Bai D, Wang M, Mei S, Cheng T, Wu L, Gao S, Che X, 2024 Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice, Shen J, Wu L, Shi X, Chen G, Liu T, Xu F, Xu X, Kou X, Zhao Y, Wang H, Wang C, Gao S, Xu S, 2024 Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Xi C, Yan Z, Bai D, Zhang Y, Wang B, Han XX, Wu L, Shi X, Hu Z, Tang M, Su Z, Liu Y, Liu B, Yin J, Wang H, Li X, Zhang Y, Gao S, Liu W, 2024 Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency, Liu D, Guan X, Liu W, Jia Y, Zhou H, Xi C, Zhao M, Fang Y, Wu L, Li K, 2023 Modeling human pregastrulation development by 3D culture of blastoids generated from primed-to-naïve transitioning intermediates, Tu Z, Bi Y, Zhu X, Liu W, Hu J, Wu L, Mao T, Zhou J, Wang H, Wang H, Gao S, Wang Y, 2023 Remodeling of H3K9me3 during the pluripotent to totipotent-like state transition, Li H, Sun J, Dong Y, Huang Y, Wu L, Xi C, Su Z, Xiao Y, Zhang C, Liang Y, Li Y, Lin Z, Shen L, Zuo Y, Abudureheman A, Yin J, Wang H, Kong X, Le R, Gao S, Zhang Y, 2023 LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Zhu J, Chen K, Sun YH, Ye W, Liu J, Zhang D, Su N, Wu L, Kou X, Zhao Y, Wang H, Gao S, Kang L, 2023 Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming, Xi C, Sun J, Xu X, Wu Y, Kou X, Zhao Y, Shen J, Dong Y, Chen K, Su Z, Liu D, Ye W, Liu Y, Zhang R, Xu Y, Wang H, Hao L, Wu L, Gao S, 2022 Enhancement of Xrcc1-mediated base excision repair improves the genetic stability and pluripotency of iPSCs, Zhao K, Sun X, Zheng C, Wang M, Xu Z, Wang M, Chen J, Guo M, Le R, Wu L, Wang Y, Kou X, Zhao Y, Yin J, Wang H, Mao Z, Gao S, Gao S, 2022 Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S, Chen K, Le R, Xi C

Areas of Focus

体细胞重编程机制研究
应用多能干细胞以及临床样本进行女性生殖系统生理病理过程的体外模拟及再生医学研究

Publications

Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics, Chen T, Xu Y, Xu X, Wang J, Qiu Z, Yu Y, Jiang X, Shao W, Bai D, Wang M, Mei S, Cheng T, Wu L, Gao S, Che X, 2024
Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice, Shen J, Wu L, Shi X, Chen G, Liu T, Xu F, Xu X, Kou X, Zhao Y, Wang H, Wang C, Gao S, Xu S, 2024
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Xi C, Yan Z, Bai D, Zhang Y, Wang B, Han XX, Wu L, Shi X, Hu Z, Tang M, Su Z, Liu Y, Liu B, Yin J, Wang H, Li X, Zhang Y, Gao S, Liu W, 2024
Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency, Liu D, Guan X, Liu W, Jia Y, Zhou H, Xi C, Zhao M, Fang Y, Wu L, Li K, 2023
Modeling human pregastrulation development by 3D culture of blastoids generated from primed-to-naïve transitioning intermediates, Tu Z, Bi Y, Zhu X, Liu W, Hu J, Wu L, Mao T, Zhou J, Wang H, Wang H, Gao S, Wang Y, 2023
Remodeling of H3K9me3 during the pluripotent to totipotent-like state transition, Li H, Sun J, Dong Y, Huang Y, Wu L, Xi C, Su Z, Xiao Y, Zhang C, Liang Y, Li Y, Lin Z, Shen L, Zuo Y, Abudureheman A, Yin J, Wang H, Kong X, Le R, Gao S, Zhang Y, 2023
LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Zhu J, Chen K, Sun YH, Ye W, Liu J, Zhang D, Su N, Wu L, Kou X, Zhao Y, Wang H, Gao S, Kang L, 2023
Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming, Xi C, Sun J, Xu X, Wu Y, Kou X, Zhao Y, Shen J, Dong Y, Chen K, Su Z, Liu D, Ye W, Liu Y, Zhang R, Xu Y, Wang H, Hao L, Wu L, Gao S, 2022
Enhancement of Xrcc1-mediated base excision repair improves the genetic stability and pluripotency of iPSCs, Zhao K, Sun X, Zheng C, Wang M, Xu Z, Wang M, Chen J, Guo M, Le R, Wu L, Wang Y, Kou X, Zhao Y, Yin J, Wang H, Mao Z, Gao S, Gao S, 2022
Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S, Chen K, Le R, Xi C

体细胞重编程机制多能干细胞临床应用体外女性生殖系统生理病理再生医学

尹晓磊 - 同济大学

祝颖慧 - 同济大学

Area of Focus
白血病 | 急性 | 发病机制 | 耐药 | 机制 | 靶向 | 免疫疗法 | 开发 | 临床应用 | 多维组学

岳锐 - 同济大学

Area of Focus
骨骼 | 干细胞 | 造血 | 微环境 | 鉴定 | 调控 | 骨质疏松 | 骨关节炎 | 年轻化 | 临床应用

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