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吴丽
Life Science
同济大学
上海
Language: 中文, 英语
体细胞
重编程
机制
多能
干细胞
临床应用
体外
女性生殖系统
生理病理
再生医学
Areas of Focus
- 体细胞重编程机制研究
- 应用多能干细胞以及临床样本进行女性生殖系统生理病理过程的体外模拟及再生医学研究
Work Experience
- 2018.02-至今 同济大学附属第一妇婴保健院 助理研究员、副研究员
- 2014.07-2018.01 同济大学/中国科学院生物物理研究所 博士生
- 2012.07-2014.06 中国科学院上海生命科学研究院 助理研究员
- 2011.07-2012.06 上海市药明康德新药开发有限公司 研究员
- 2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心 硕士生
Academic Background & Achievements
- 2014.07-2018.01 同济大学/中国科学院生物物理研究所 生物化学与分子生物学博士
- 2007.09-2011.06 华东师范大学/中国科学院上海药物所国家新药筛选中心 生物医学硕士
- 2002.09-2006.06 石河子大学 食品工程学院 工学学士
Publications
- Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics, Chen T, Xu Y, Xu X, Wang J, Qiu Z, Yu Y, Jiang X, Shao W, Bai D, Wang M, Mei S, Cheng T, Wu L, Gao S, Che X, 2024
- Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice, Shen J, Wu L, Shi X, Chen G, Liu T, Xu F, Xu X, Kou X, Zhao Y, Wang H, Wang C, Gao S, Xu S, 2024
- Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Xi C, Yan Z, Bai D, Zhang Y, Wang B, Han XX, Wu L, Shi X, Hu Z, Tang M, Su Z, Liu Y, Liu B, Yin J, Wang H, Li X, Zhang Y, Gao S, Liu W, 2024
- Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency, Liu D, Guan X, Liu W, Jia Y, Zhou H, Xi C, Zhao M, Fang Y, Wu L, Li K, 2023
- Modeling human pregastrulation development by 3D culture of blastoids generated from primed-to-naïve transitioning intermediates, Tu Z, Bi Y, Zhu X, Liu W, Hu J, Wu L, Mao T, Zhou J, Wang H, Wang H, Gao S, Wang Y, 2023
- Remodeling of H3K9me3 during the pluripotent to totipotent-like state transition, Li H, Sun J, Dong Y, Huang Y, Wu L, Xi C, Su Z, Xiao Y, Zhang C, Liang Y, Li Y, Lin Z, Shen L, Zuo Y, Abudureheman A, Yin J, Wang H, Kong X, Le R, Gao S, Zhang Y, 2023
- LSM1-mediated Major Satellite RNA decay is required for nonequilibrium histone H3.3 incorporation into parental pronuclei, Zhu J, Chen K, Sun YH, Ye W, Liu J, Zhang D, Su N, Wu L, Kou X, Zhao Y, Wang H, Gao S, Kang L, 2023
- Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming, Xi C, Sun J, Xu X, Wu Y, Kou X, Zhao Y, Shen J, Dong Y, Chen K, Su Z, Liu D, Ye W, Liu Y, Zhang R, Xu Y, Wang H, Hao L, Wu L, Gao S, 2022
- Enhancement of Xrcc1-mediated base excision repair improves the genetic stability and pluripotency of iPSCs, Zhao K, Sun X, Zheng C, Wang M, Xu Z, Wang M, Chen J, Guo M, Le R, Wu L, Wang Y, Kou X, Zhao Y, Yin J, Wang H, Mao Z, Gao S, Gao S, 2022
- Surf4 facilitates reprogramming by activating the cellular response to endoplasmic reticulum stress, Wu L, He S, Ye W, Shen J, Zhao K, Zhang Y, Zhang R, Wei J, Cao S, Chen K, Le R, Xi C
