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洪学传
Medical School
武汉大学
湖北省
Language: 英语, 汉语
Nir-Ii 探针
有机分子
小分子
肿瘤可视化
病毒机制
药物开发
分子成像
生物医学成像
癌症研究
治疗剂
Areas of Focus
- 近红外二区有机小分子探针的制造，可视化肿瘤、病毒感染机制研究及药物开发
Work Experience
- 2017.12 – 至今 西藏大学医学院教授，博士生导师
- 2010.10 – 至今 武汉大学药学院教授，博士生导师
- 2007.10–2010.10 美国 AMRI，资深研究员
- 2005.09–2007.09 美国爱默里大学化学系，博士后研究员
- 1999.12–2000.07 日本北海道大学，药学院，研修生
Academic Background & Achievements
- 2001.01–2005.07 密苏里大学哥伦比亚分校化学系，博士学位
- 1997.09–1999.11 天津大学化工学院，硕士学位
- 1993.09–1997.07 天津大学应用化学系，本科学位
- 1993.09–1997.07 天津大学管理学院技术经济学系，本科学位
Publications
- Polymethine thiopyrylium fluorophores with absorption beyond 1000 nm for biological imaging in the second near-infrared sub-window, 洪学传*, 2019
- Pyrazolopyrimidines as potent stimulators for transient receptor potential canonical 3/6/7 channels, 洪学传*, 2017
- A small molecule dye for NIR II imaging, 洪学传*, 2016
- Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, 洪学传*, 2015
- A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, 洪学传*, 2017
- Dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery, 洪学传*, 2018
- Novel near-Infrared II aggregation-induced emission dots for in vivo bioimaging, 洪学传*, 2019
- Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery, 洪学传*, 2017
- Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer, 洪学传*, 2016
- Recyclable Cu(I)/Melanin dots for cycloadditions, bioconjugation and cell labeling, 洪学传*, 2016
- Metal-free direct amidation of peptidyl thiol esters with amino acid esters, 洪学传*, 2011
- Quaternary ammonium salt based NIR-II probes for In vivo imaging, 洪学传*, 2019
- Mn-loaded apolactoferrin dots for in vivo MRI and NIR-II cancer imaging, 洪学传*, 2019
- Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels, 洪学传*, 2015
- Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer, 洪学传*, 2018
- Near-Infrared II dye-protein complex for biomedical imaging and imaging-guided photothermal therapy, 洪学传*, 2018
- A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection, 洪学传*, 2019
- New glowing dyes in vivo imaging with wavelengths beyond 1500 nm, 洪学传*, 2019
- Design, synthesis and pharmacological evaluation of novel N-(2-(1,1-dimethyl-5, 7-dioxo-4, 6-diazaspiro[2.4]heptan-6-yl)ethyl) sulfonamide derivatives as potential anticonvulsant agents, 洪学传*, 2015
- Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors, 洪学传*, 2014
Awards
- 2018年度西藏大学优秀工作者
- 2017-2018年度西藏大学医学院优秀论文特别贡献奖
- 2016年获武汉大学朱裕璧医学奖
- 2016年武汉大学珞珈学者特聘教授
- 2016年获武汉大学医学部医学突出贡献奖
- 2015年获武汉大学医学部医学突出贡献奖
- 2014年获武汉市第三批“黄鹤英才”人才计划
- 2014年获美国化学会组织颁发的第九届世界华人药学会最佳报告奖
