Professor | 洪学传 | 数字化转型顾问

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Name	洪学传
Contact Information	Xhy78@whu.edu.cn
Language ability	英语, 汉语
Province	湖北省

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Name

洪学传

Contact Information

Xhy78@whu.edu.cn

Language ability

英语, 汉语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	2001.01–2005.07 密苏里大学哥伦比亚分校化学系，博士学位 1997.09–1999.11 天津大学化工学院，硕士学位 1993.09–1997.07 天津大学应用化学系，本科学位 1993.09–1997.07 天津大学管理学院技术经济学系，本科学位
Work Experience	2017.12 – 至今西藏大学医学院教授，博士生导师 2010.10 – 至今武汉大学药学院教授，博士生导师 2007.10–2010.10 美国 AMRI，资深研究员 2005.09–2007.09 美国爱默里大学化学系，博士后研究员 1999.12–2000.07 日本北海道大学，药学院，研修生
Awards	2018年度西藏大学优秀工作者 2017-2018年度西藏大学医学院优秀论文特别贡献奖 2016年获武汉大学朱裕璧医学奖 2016年武汉大学珞珈学者特聘教授 2016年获武汉大学医学部医学突出贡献奖 2015年获武汉大学医学部医学突出贡献奖 2014年获武汉市第三批“黄鹤英才”人才计划 2014年获美国化学会组织颁发的第九届世界华人药学会最佳报告奖

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

2001.01–2005.07 密苏里大学哥伦比亚分校化学系，博士学位
1997.09–1999.11 天津大学化工学院，硕士学位
1993.09–1997.07 天津大学应用化学系，本科学位
1993.09–1997.07 天津大学管理学院技术经济学系，本科学位

Work Experience

2017.12 – 至今西藏大学医学院教授，博士生导师
2010.10 – 至今武汉大学药学院教授，博士生导师
2007.10–2010.10 美国 AMRI，资深研究员
2005.09–2007.09 美国爱默里大学化学系，博士后研究员
1999.12–2000.07 日本北海道大学，药学院，研修生

Awards

2018年度西藏大学优秀工作者
2017-2018年度西藏大学医学院优秀论文特别贡献奖
2016年获武汉大学朱裕璧医学奖
2016年武汉大学珞珈学者特聘教授
2016年获武汉大学医学部医学突出贡献奖
2015年获武汉大学医学部医学突出贡献奖
2014年获武汉市第三批“黄鹤英才”人才计划
2014年获美国化学会组织颁发的第九届世界华人药学会最佳报告奖

Areas of Focus	近红外二区有机小分子探针的制造，可视化肿瘤、病毒感染机制研究及药物开发
Publications	Polymethine thiopyrylium fluorophores with absorption beyond 1000 nm for biological imaging in the second near-infrared sub-window, 洪学传, 2019 Pyrazolopyrimidines as potent stimulators for transient receptor potential canonical 3/6/7 channels, 洪学传, 2017 A small molecule dye for NIR II imaging, 洪学传, 2016 Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, 洪学传, 2015 A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, 洪学传, 2017 Dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery, 洪学传, 2018 Novel near-Infrared II aggregation-induced emission dots for in vivo bioimaging, 洪学传, 2019 Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery, 洪学传, 2017 Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer, 洪学传, 2016 Recyclable Cu(I)/Melanin dots for cycloadditions, bioconjugation and cell labeling, 洪学传, 2016 Metal-free direct amidation of peptidyl thiol esters with amino acid esters, 洪学传, 2011 Quaternary ammonium salt based NIR-II probes for In vivo imaging, 洪学传, 2019 Mn-loaded apolactoferrin dots for in vivo MRI and NIR-II cancer imaging, 洪学传, 2019 Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels, 洪学传, 2015 Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer, 洪学传, 2018 Near-Infrared II dye-protein complex for biomedical imaging and imaging-guided photothermal therapy, 洪学传, 2018 A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection, 洪学传, 2019 New glowing dyes in vivo imaging with wavelengths beyond 1500 nm, 洪学传, 2019 Design, synthesis and pharmacological evaluation of novel N-(2-(1,1-dimethyl-5, 7-dioxo-4, 6-diazaspiro[2.4]heptan-6-yl)ethyl) sulfonamide derivatives as potential anticonvulsant agents, 洪学传, 2015 Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors, 洪学传, 2014

Areas of Focus

近红外二区有机小分子探针的制造，可视化肿瘤、病毒感染机制研究及药物开发

Publications

Polymethine thiopyrylium fluorophores with absorption beyond 1000 nm for biological imaging in the second near-infrared sub-window, 洪学传*, 2019
Pyrazolopyrimidines as potent stimulators for transient receptor potential canonical 3/6/7 channels, 洪学传*, 2017
A small molecule dye for NIR II imaging, 洪学传*, 2016
Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, 洪学传*, 2015
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, 洪学传*, 2017
Dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery, 洪学传*, 2018
Novel near-Infrared II aggregation-induced emission dots for in vivo bioimaging, 洪学传*, 2019
Novel bright-emission small-molecule NIR-II fluorophores for in vivo tumor imaging and image-guided surgery, 洪学传*, 2017
Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer, 洪学传*, 2016
Recyclable Cu(I)/Melanin dots for cycloadditions, bioconjugation and cell labeling, 洪学传*, 2016
Metal-free direct amidation of peptidyl thiol esters with amino acid esters, 洪学传*, 2011
Quaternary ammonium salt based NIR-II probes for In vivo imaging, 洪学传*, 2019
Mn-loaded apolactoferrin dots for in vivo MRI and NIR-II cancer imaging, 洪学传*, 2019
Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels, 洪学传*, 2015
Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer, 洪学传*, 2018
Near-Infrared II dye-protein complex for biomedical imaging and imaging-guided photothermal therapy, 洪学传*, 2018
A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection, 洪学传*, 2019
New glowing dyes in vivo imaging with wavelengths beyond 1500 nm, 洪学传*, 2019
Design, synthesis and pharmacological evaluation of novel N-(2-(1,1-dimethyl-5, 7-dioxo-4, 6-diazaspiro[2.4]heptan-6-yl)ethyl) sulfonamide derivatives as potential anticonvulsant agents, 洪学传*, 2015
Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors, 洪学传*, 2014

Nir-Ii 探针有机分子小分子肿瘤可视化病毒机制药物开发分子成像生物医学成像癌症研究治疗剂

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